Lidocaine Hydrochloride

Product NDC
10135-736
11-digit product format
101350736
Labeler code
10135
Product ID
10135-736_4260de8c-7ec7-00d0-e063-6394a90aeebd
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lidocaine Hydrochloride
Dosage form
SOLUTION
Route
TOPICAL
Labeler
Marlex Pharmaceuticals, Inc.
Application
ANDA216250
Marketing category
ANDA
Marketing start
2022-06-01
Substance
LIDOCAINE HYDROCHLORIDE
Active strength
40 mg/mL
Pharmacologic classes
Amide Local Anesthetic [EPC], Amides [CS], Antiarrhythmic [EPC], Local Anesthesia [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216250-001LIDOCAINE HYDROCHLORIDELIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A216250-001AT

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-235d02ea3f76ae…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-239b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-233f0d92c62455…
2023-05-13 08:27 UTC2023-05A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23053a50430f4f…
2023-01-26 05:58 UTC2023-01A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-233bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-233a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216250-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2022-03-23a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A216250-001AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A216250-001AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08A216250-001AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A216250-001AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A216250-001AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A216250-001AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A216250-001AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A216250-001AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A216250-001AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A216250-001AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A216250-001AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A216250-001AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A216250-001AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A216250-001AT18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A216250-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A216250-001AT15d02ea3f76ae…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A216250-001AT16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A216250-001AT11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A216250-001AT1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A216250-001AT1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A216250-001AT19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A216250-001AT1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A216250-001AT13f0d92c62455…
2023-05-13 08:27 UTC2023-05A216250-001AT1053a50430f4f…
2023-01-26 05:58 UTC2023-01A216250-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A216250-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A216250-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A216250-001AT1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A216250-001AT1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A216250-001AT1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Lidocaine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LIDOCAINE HYDROCHLORIDE40 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V13007Z41AInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1010878Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e1badbba-59af-e451-e053-2a95a90a49f8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
860a93dc-4863-49cc-b284-6bbe8191bc48Product name420250214
eaba870a-6a9d-442e-8643-87b3f558a451Product name120250117
9b4cf230-fd05-41d5-98c6-5db9ecb27b86Product name120230117
fa8b5901-e681-426f-82fe-54f6d81ec698Product name420180619
332d03e4-aa24-4b11-841a-02bf41081920Product name120171221
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070Product name120171221
68ed98f8-24c2-44a0-944a-6d36e82ce25aProduct name120141222
1cd42bc2-a430-c72b-636d-991b235fbf80Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
10135-736-51Lidocaine Hydrochloride1 in 1 CARTONSOLUTION13
10135-736-51Lidocaine Hydrochloride50 mL in 1 BOTTLESOLUTION503

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
10135-736-51ML - Milliliter10135-73624847f7c-1cf8-46a1-a386-27075e91bc8912022-07-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
10135-736LIDOCAINE HYDROCHLORIDE SOLUTION [MARLEX PHARMACEUTICALS, INC.]2Current NDC, Legacy NDC, 2 package rows20231116_e1badbba-59af-e451-e053-2a95a90a49f8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Lidocaine HydrochlorideLIDOCAINE HYDROCHLORIDEMarlex Pharmaceuticals, Inc.e1badbba-59af-e451-e053-2a95a90a49f82025-10-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216250
application number: ANDA216250
ndc (product): 10135-736
Lidocaine HydrochlorideLIDOCAINE HYDROCHLORIDENovitium Pharma LLCffb2d794-2c88-48a2-beff-d01b6fcea51f2022-03-25Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216250
application number: ANDA216250

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1010878lidocaine HCl 4 % Mucous Membrane Topical SolutionPSNe1badbba-59af-e451-e053-2a95a90a49f83
1010878lidocaine hydrochloride 40 MG/ML Mucous Membrane Topical SolutionSCDe1badbba-59af-e451-e053-2a95a90a49f83
1010878lidocaine hydrochloride 4 % Mucous Membrane Topical SolutionSYe1badbba-59af-e451-e053-2a95a90a49f83
1010878lidocaine hydrochloride 4 % Oromucosal SolutionSYe1badbba-59af-e451-e053-2a95a90a49f83

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
10135-736-51101350736511 BOTTLE in 1 CARTON (10135-736-51) / 50 mL in 1 BOTTLE1 bottle2022-06-010000-00-00NoNoCurrent