Anti-Diarrheal

Product NDC
11822-0375
Requested package NDC
11822-0375-8
11-digit product format
118220375
Labeler code
11822
Product ID
11822-0375_6e4a0f4e-4add-47b0-bb46-e1e120a608ec
Type
HUMAN OTC DRUG
Nonproprietary name
Loperamide HCl
Dosage form
TABLET
Route
ORAL
Labeler
Rite Aid Corporation
Application
ANDA076497
Marketing category
ANDA
Marketing start
2005-05-03
Substance
LOPERAMIDE HYDROCHLORIDE
Active strength
2 mg/1
Pharmacologic classes
Opioid Agonist [EPC], Opioid Agonists [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076497-001LOPERAMIDE HYDROCHLORIDELOPERAMIDE HYDROCHLORIDE2MGTABLET / ORAL2003-06-10

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06A076497-001LOPERAMIDE HYDROCHLORIDE2MGTABLET / ORAL2003-06-10a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 2 · 35 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Anti DiarrhealLOPERAMIDE HCLYyba Corpe3b0a274-8bf9-4d39-a805-97fecca607f62026-07-13WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLWalgreen Company31f9b652-e9c9-46ed-a46c-22d30ad110042026-07-10WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-diarrhealLOPERAMIDE HCLL.N.K. International, Inc.e34f5bbc-e43c-a69e-e94d-ebc3195182042026-06-23WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLDiscount Drug Mart91843b17-3c04-482c-a2ba-143193be15952026-06-08WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti DiarrhealLOPERAMIDE HCLARMY AND AIR FORCE EXCHANGE SERVICEf93a1f1f-2233-4338-9643-1ba48bd000bc2026-06-03WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLFamily Dollar Services Inc769e7182-fa11-4645-8fca-657253f28d9c2026-05-27WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLH E B8f7fea50-70cf-4f9f-a655-30371e5b9d9f2026-05-19WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti DiarrhealLOPERAMIDE HCLChain Drug Marketing Association, Inc.dd993f38-a31f-4739-9496-e14186a890532026-05-18WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLUnited Natural Foods, Inc. dba UNFIf16e07f3-0efb-4451-adbb-e427f9abc7ae2026-05-18WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HYDROCHLORIDEIMO-GEN LABS LLC1b5f2c7c-baf0-b213-e063-6394a90a25df2026-04-21WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLValu Merchandisers Company70a7f827-f5be-454f-99bf-a7fd1037694e2026-04-21WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLWinCo Foods, LLC3990279b-45ee-49cf-9ecf-9ce23731b59a2026-04-17WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLHeartland Pharma Co.e360ba61-556a-4d7f-ab2e-2cb71656d8682026-04-17WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLGrocery Outlet94279e1f-5d87-40ba-8b4b-56930fdc3e3a2026-03-19WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLRite Aid Corporationc6cc4ba7-0e7a-4dd6-a5cf-b7e16e1a6c752026-03-11WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
ndc (package): 11822-0375-8
ndc (product): 11822-0375
ndc11 (package): 11822037508
Anti DiarrhealLOPERAMIDE HCLWal-Mart Stores Incb480916e-6383-468d-9e3e-499efea925222026-01-19WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
ANTI-DIARRHEALLOPERAMIDE HCLAdvanced Rx LLC148cb6b7-28e7-48e9-b464-f42daa90e5da2025-11-04WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLBetter Living Brands, LLC8d3ccda2-3886-4ff7-ad10-6440fc4da6bf2025-10-28WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
Anti-DiarrhealLOPERAMIDE HCLL.N.K. International, Inc.c03a9389-8b33-4ade-8ba0-8f303e161a082025-10-06WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497
First Aid Direct Anti-DiarrhealFIRST AID DIRECT ANTI-DIARRHEALCintas Corp942b5af1-835e-41dd-bf65-e5b68352aa462025-09-29WarningsExact identifier
application applno (ANDA): 076497
application number: ANDA076497

Additional Listing Data#

Finished product
Yes
Brand name base
Anti-Diarrheal
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LOPERAMIDE HYDROCHLORIDE2 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
77TI35393CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
978010Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c6cc4ba7-0e7a-4dd6-a5cf-b7e16e1a6c75Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
10f838ef-a72b-645d-80f8-e2255205c3b1Product name620240805

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
11822-0375-3Anti-Diarrheal6 in 1 BLISTER PACKTABLET628
11822-0375-3Anti-Diarrheal2 in 1 CARTONTABLET228
11822-0375-5Anti-Diarrheal1 in 1 CARTONTABLET128
11822-0375-5Anti-Diarrheal2 in 1 BLISTER PACKTABLET228
11822-0375-8Anti-Diarrheal6 in 1 BLISTER PACKTABLET628
11822-0375-8Anti-Diarrheal4 in 1 CARTONTABLET428

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
LOPERAMIDE HYDROCHLORIDEACTIVE INGREDIENT77TI35393CANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9
LOPERAMIDEACTIVE MOIETY6X9OC3H4IIANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9
FD&C BLUE NO. 1INACTIVE INGREDIENTH3R47K3TBDANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30ANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID]9

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
11822-0375ANTI-DIARRHEAL (LOPERAMIDE HCL) TABLET [RITE AID CORPORATION]27Current NDC, Legacy NDC, 6 package rows20250331_c6cc4ba7-0e7a-4dd6-a5cf-b7e16e1a6c75.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
978010loperamide HCl 2 MG Oral TabletPSNc6cc4ba7-0e7a-4dd6-a5cf-b7e16e1a6c7528
978010loperamide hydrochloride 2 MG Oral TabletSCDc6cc4ba7-0e7a-4dd6-a5cf-b7e16e1a6c7528

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
11822-0375-8118220375084 BLISTER PACK in 1 CARTON (11822-0375-8) / 6 TABLET in 1 BLISTER PACK4 blister pack2005-05-030000-00-00NoNoCurrent