Pain Relief Acetaminophen PM

Product NDC: 11822-0556
11-digit product format: 118220556
Labeler code: 11822
Product ID: 11822-0556_d7058f45-483c-4b4d-a1ce-41c52c43a654
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen and Diphenhydramine HCl
Dosage form: TABLET, COATED
Route: ORAL
Labeler: Rite Aid Corporation
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2007-12-17
Substance: ACETAMINOPHEN; DIPHENHYDRAMINE HYDROCHLORIDE
Active strength: 500; 25 mg/1; mg/1
Pharmacologic classes: Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	11822-0556	11822-0556-3	D	Discontinued by firm		2026-10-20
excluded package	package	11822-0556	11822-0556-9	D	Discontinued by firm		2026-10-20

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	11822-0556-9	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	11822-0556-3	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	11822-0556-9	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	11822-0556-3	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	11822-0556-9	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	11822-0556-3	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	11822-0556-9	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	11822-0556-3	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	11822-0556-9	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	11822-0556-3	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	11822-0556-9	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	11822-0556-3	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	11822-0556-9	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	11822-0556-3	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	11822-0556-9	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	11822-0556-3	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	11822-0556-9	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	11822-0556-3	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	11822-0556-9	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	11822-0556-3	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	11822-0556-9	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	11822-0556-3	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	11822-0556-9	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	11822-0556-3	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Pain Relief Acetaminophen PM
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	500 mg/1
DIPHENHYDRAMINE HYDROCHLORIDE	25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup
TC2D6JAD40	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1092189	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
f77f0120-4042-4b11-ba9c-cd35e1cd0bee	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
11822-0556-1	Pain Relief Acetaminophen PM	80 in 1 BOTTLE, PLASTIC	TABLET, COATED	80	20
11822-0556-3	Pain Relief Acetaminophen PM	80 in 1 BOTTLE, PLASTIC	TABLET, COATED	80	20
11822-0556-3	Pain Relief Acetaminophen PM	1 in 1 CARTON	TABLET, COATED	1	20
11822-0556-9	Pain Relief Acetaminophen PM	20 in 1 BOTTLE, PLASTIC	TABLET, COATED	20	20
11822-0556-9	Pain Relief Acetaminophen PM	1 in 1 CARTON	TABLET, COATED	1	20

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
ACETAMINOPHEN	ACTIVE INGREDIENT	362O9ITL9D	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
ACETAMINOPHEN	ACTIVE MOIETY	362O9ITL9D	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
CROSCARMELLOSE SODIUM	INACTIVE INGREDIENT	M28OL1HH48	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
FD&C BLUE NO. 1	INACTIVE INGREDIENT	H3R47K3TBD	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
FD&C RED NO. 3	INACTIVE INGREDIENT	PN2ZH5LOQY	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
HYDROXYPROPYL CELLULOSE (TYPE H)	INACTIVE INGREDIENT	RFW2ET671P	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
POLYETHYLENE GLYCOLS	INACTIVE INGREDIENT	3WJQ0SDW1A	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET [RITE AID]	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
11822-0556	PAIN RELIEF ACETAMINOPHEN PM (ACETAMINOPHEN AND DIPHENHYDRAMINE HCL) TABLET, COATED [RITE AID CORPORATION]	19	Current NDC, Legacy NDC, 5 package rows	20250105_f77f0120-4042-4b11-ba9c-cd35e1cd0bee.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 9 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Aspirin Low Dose	ASPIRIN	ARMY AND AIR FORCE EXCHANGE SERVICE	e273ead7-7cbc-4fd5-a136-9d3558a35360	2026-06-24	Warnings	Exact identifier application number: M013
Acetaminophen Regular Strength	ACETAMINOPHEN	CVS PHARMACY	5e35df92-6282-4ca6-902b-bb6bd326b487	2026-06-23	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	Orelli Inc.	4f9f1b4e-8bbb-49b9-8e6c-263edb2c084d	2026-06-22	Warnings	Exact identifier application number: M013
Pain Relief Aspirin Chewable, Low Dose	ASPIRIN	Rite Aid Corporation	65cdce0f-be04-43ba-8c68-bdce7983cfa1	2026-06-22	Warnings	Exact identifier application number: M013
Aspirin Regimen	ASPIRIN	Cardinal Health 110, LLC. DBA Leader	88f425df-712d-4911-824b-94085c7190b6	2026-06-19	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	Meijer Distribution, Inc.	3716a7d4-a555-4e54-aa0a-7b8f3e32addb	2026-06-19	Warnings	Exact identifier application number: M013
Pain Relief	ACETAMINOPHEN	DOLGENCORP, LLC	acc94a3e-21b6-4375-9881-38cf9bab8692	2026-06-19	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	L.N.K. International, Inc.	2f6ec676-3832-420e-be91-fce83f6586c8	2026-06-19	Warnings	Exact identifier application number: M013
Headache Relief	ACETAMINOPHEN, ASPIRIN, CAFFEINE	DOLGENCORP, LLC	e1e24d52-0b4d-400b-8181-e3f6ab75c4f6	2026-06-18	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	Oncor Pharmaceuticals	4c396d0e-aa93-4f9e-b065-2e606f7f05cd	2026-06-17	Warnings	Exact identifier application number: M013
LOW DOSE ASPIRIN	ASPIRIN	Famora Inc.	4dc6f119-bbde-db5f-e063-6294a90a9486	2026-06-16	Warnings	Exact identifier application number: M013
Childrens Pain and Fever Relief	ACETAMINOPHEN	Chain Drug Marketing Association, Inc.	420a1e05-caa6-481f-bdab-a670f0220f96	2026-06-16	Warnings	Exact identifier application number: M013
Pain Relief Extra Strength	ACETAMINOPHEN	DOLGENCORP, LLC	ce9f4e0d-43fb-499a-b8a2-a997a14841c4	2026-06-16	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	L.N.K. International, Inc.	734cc3d2-6fc5-4dcc-93ed-0b57c1f01345	2026-06-15	Warnings	Exact identifier application number: M013
RIGHT REMEDIES EXTRA STRENGTH Pain Relief PM Caplet	ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Strive Pharmaceuticals Inc.	2d63671d-cf7c-bbdd-e063-6294a90affef	2026-06-15	Warnings	Exact identifier application number: M013
TYLENOL Extra Strength	ACETAMINOPHEN	Kenvue Brands LLC	59773893-09a8-47a2-943a-e9ea9da4458a	2026-06-15	Warnings	Exact identifier application number: M013
Pain Relief	ACETAMINOPHEN	Shield Pharmaceuticals Corp.	96eb7f9f-ff2d-4661-bbe6-1860aafe03f6	2026-06-15	Warnings	Exact identifier application number: M013
Duralgina Extra Strength	ACETAMINOPHEN	Menper Distributors, Inc.	544e3d7e-a759-384f-e063-6294a90a5baa	2026-06-15	Warnings	Exact identifier application number: M013
pain relief childrens	ACETAMINOPHEN	Rite Aid Corporation	be2286a1-946b-4bf5-b14c-8e86da669594	2026-06-15	Warnings	Exact identifier application number: M013
Aspirin 81	ASPIRIN	Amerisource Bergen	4491faca-f30b-4eb0-bea9-f518f6b2f095	2026-06-15	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1092189	acetaminophen 500 MG / diphenhydrAMINE HCl 25 MG Oral Tablet	PSN	f77f0120-4042-4b11-ba9c-cd35e1cd0bee	20
1092189	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet	SCD	f77f0120-4042-4b11-ba9c-cd35e1cd0bee	20
1092189	APAP 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet	SY	f77f0120-4042-4b11-ba9c-cd35e1cd0bee	20

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
11822-0556-1	11822055601	80 TABLET, COATED in 1 BOTTLE, PLASTIC (11822-0556-1)	2007-12-17	0000-00-00	No	No	Current
11822-0556-3	11822055603	80 in 1 BOTTLE, PLASTIC					Historical
11822-0556-9	11822055609	20 in 1 BOTTLE, PLASTIC					Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Rite Aid 44-556	Rite Aid Corporation \| LNK International, Inc.	2026-01-05	HUMAN OTC DRUG LABEL	20