DEFINITY RT

Product NDC
11994-017
11-digit product format
119940017
Labeler code
11994
Product ID
11994-017_4d13e254-dcc7-460c-9adc-1c812562cef7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
perflutren
Dosage form
INJECTION, SUSPENSION
Route
INTRAVENOUS
Labeler
Lantheus Medical Imaging, Inc.
Application
NDA021064
Marketing category
NDA
Marketing start
2020-10-01
Substance
PERFLUTREN
Active strength
6.52 mg/mL
Pharmacologic classes
Contrast Agent for Ultrasound Imaging [EPC], Ultrasound Contrast Activity [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021064-001DEFINITYPERFLUTREN13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31
N021064-002DEFINITY RTPERFLUTREN13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17

Orange Book patents#

Current patent rows page 1 of 1 · 20 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N021064-001105832072035-12-28U-6652020-04-08
N021064-001105832082037-03-16U-6652020-04-08
N021064-001112667502037-03-16U-6652022-03-18
N021064-001115294312037-03-16U-6652023-01-09
N021064-001118576462037-03-16U-6652024-01-12
N021064-001119256952037-03-16U-6652024-03-22
N021064-001121617302037-03-16U-6652025-01-06
N021064-00197892102037-03-16U-6652017-10-19
N021064-001105889882037-05-04U-6652020-04-08
N021064-002100224602035-12-28Drug substance, Drug product2020-12-16
N021064-002105832072035-12-28U-6652020-12-16
N021064-002113958562035-12-28U-665Drug substance, Drug product2022-08-18
N021064-002105832082037-03-16U-6652020-12-16
N021064-002112667502037-03-16U-6652022-03-18
N021064-002115294312037-03-16U-6652023-01-09
N021064-002118576462037-03-16U-6652024-01-12
N021064-002119256952037-03-16U-6652024-03-22
N021064-002121617302037-03-16U-6652025-01-06
N021064-00297892102037-03-16U-6652020-12-16
N021064-002105889882037-05-04U-6652020-12-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 78 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-312680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-315bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31d06236e962d9…
2024-10-29 15:01 UTC2024-10N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-3179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-31301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-311e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021064-001DEFINITY13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2001-07-318072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021064-002DEFINITY RT13.04MG/2ML (6.52MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2020-11-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-315c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021064-002DEFINITY RT6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2020-11-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-315d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021064-002DEFINITY RT6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2020-11-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-314b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021064-002DEFINITY RT6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2020-11-174b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-3174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-31bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021064-002DEFINITY RT6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2020-11-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021064-001DEFINITY6.52MG/MLINJECTABLE / INTRAVENOUSRLD, RS2001-07-31782e0a99824c…

Observed Orange Book patent history#

Patent history page 1 of 15 · 572 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N021064-001105832072035-12-28U-6652020-04-08caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001105832082037-03-16U-6652020-04-08caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001112667502037-03-16U-6652022-03-18caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001115294312037-03-16U-6652023-01-09caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001118576462037-03-16U-6652024-01-12caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001119256952037-03-16U-6652024-03-22caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001121617302037-03-16U-6652025-01-06caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-00197892102037-03-16U-6652017-10-19caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-001105889882037-05-04U-6652020-04-08caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002100224602035-12-28Drug substance, Drug product2020-12-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002105832072035-12-28U-6652020-12-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002113958562035-12-28U-665Drug substance, Drug product2022-08-18caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002105832082037-03-16U-6652020-12-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002112667502037-03-16U-6652022-03-18caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002115294312037-03-16U-6652023-01-09caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002118576462037-03-16U-6652024-01-12caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002119256952037-03-16U-6652024-03-22caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002121617302037-03-16U-6652025-01-06caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-00297892102037-03-16U-6652020-12-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021064-002105889882037-05-04U-6652020-12-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021064-001105832072035-12-28U-6652020-04-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001105832082037-03-16U-6652020-04-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001112667502037-03-16U-6652022-03-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001115294312037-03-16U-6652023-01-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001118576462037-03-16U-6652024-01-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001119256952037-03-16U-6652024-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001121617302037-03-16U-6652025-01-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-00197892102037-03-16U-6652017-10-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-001105889882037-05-04U-6652020-04-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002100224602035-12-28Drug substance, Drug product2020-12-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002105832072035-12-28U-6652020-12-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002113958562035-12-28U-665Drug substance, Drug product2022-08-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002105832082037-03-16U-6652020-12-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002112667502037-03-16U-6652022-03-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002115294312037-03-16U-6652023-01-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002118576462037-03-16U-6652024-01-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002119256952037-03-16U-6652024-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002121617302037-03-16U-6652025-01-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-00297892102037-03-16U-6652020-12-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021064-002105889882037-05-04U-6652020-12-16011fe1cb6892…

Additional Listing Data#

Finished product
Yes
Brand name base
DEFINITY RT
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PERFLUTREN6.52 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
CK0N3WH0SRInternal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7b9de6ab-a3ac-40c9-8103-139dc7a464a2Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2fba083a-ac45-40d7-827d-d9f5894339f0Product name120260223
a21a21e5-f36d-4c1f-8918-def921b8f7e3Product name320250124
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
5143a3a4-d9d5-61be-0e87-2a8d497b99a6Product name120140508
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
11994-017-01DEFINITY RT0.35 mL in 1 VIAL, GLASSINJECTION, SUSPENSION0.359
11994-017-01DEFINITY RT1 in 1 CARTONINJECTION, SUSPENSION19
11994-017-20DEFINITY RT0.35 mL in 1 VIAL, GLASSINJECTION, SUSPENSION0.359
11994-017-20DEFINITY RT20 in 1 CARTONINJECTION, SUSPENSION209

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
11994-017-01ML - Milliliter11994-0179cece62c-0988-49dc-9a24-1b3e8a9f4ee512022-02-07
11994-017-20ML - Milliliter11994-0175f1bf733-0cda-4a24-a72b-4dc2d8bfc43d12022-02-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
11994-017DEFINITY RT (PERFLUTREN) INJECTION, SUSPENSION [LANTHEUS MEDICAL IMAGING, INC.]9Current NDC, Legacy NDC, 4 package rows20240316_7b9de6ab-a3ac-40c9-8103-139dc7a464a2.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DEFINITY RTPERFLUTRENLantheus Medical Imaging, Inc.7b9de6ab-a3ac-40c9-8103-139dc7a464a22024-03-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021064
application number: NDA021064
ndc (product): 11994-017
DefinityPERFLUTRENLantheus Medical Imaging, Inc.8ab9c79c-1b5c-4e86-899c-cc74686f070a2024-03-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021064
application number: NDA021064

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
11994-017-01119940017011 VIAL, GLASS in 1 CARTON (11994-017-01) / .35 mL in 1 VIAL, GLASS2020-10-010000-00-00NoNoCurrent
11994-017-161199400171616 VIAL, GLASS in 1 CARTON (11994-017-16) > .35 mL in 1 VIAL, GLASS2020-10-010000-00-00NoNoCurrent
11994-017-201199400172020 VIAL, GLASS in 1 CARTON (11994-017-20) / .35 mL in 1 VIAL, GLASS2020-10-010000-00-00NoNoCurrent