Fluocinolone acetonide 0.01%

Product NDC
13925-508
11-digit product format
139250508
Labeler code
13925
Product ID
13925-508_dfb898fc-1e28-4c46-ab2e-16139107ac4f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
fluocinolone acetonide
Dosage form
OIL
Route
AURICULAR (OTIC)
Labeler
Seton Pharmaceuticals
Application
NDA019452
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2013-08-01
Marketing end
0000-00-00
Substance
FLUOCINOLONE ACETONIDE
Active strength
0 mg/mL
Pharmacologic classes
Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]
NDC exclude flag
No
Listing certified through
2019-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct13925-508DDiscontinued by firm2026-08-07
excluded packagepackage13925-50813925-508-20DDiscontinued by firm2026-08-07

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 16 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCCodeStatusSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductDDiscontinued by firmd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage13925-508-20DDiscontinued by firmd630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductDDiscontinued by firmf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage13925-508-20DDiscontinued by firmf5e01cc5f278…a2eaf40c39c3…
2022-08-30 03:57 UTC · source 2022-08-29excluded productproductIInactivated by FDAfb8cb913e6d1…eb8c232b6be0…
2022-08-30 03:57 UTC · source 2022-08-29excluded packagepackage13925-508-20IInactivated by FDAfb8cb913e6d1…eb8c232b6be0…
2022-04-09 23:13 UTC · source 2022-04-08excluded productproductIInactivated by FDA86f5da6cb304…a595104c45d7…
2022-04-09 23:13 UTC · source 2022-04-08excluded packagepackage13925-508-20IInactivated by FDA86f5da6cb304…a595104c45d7…
2022-04-04 05:40 UTC · source 2022-04-01excluded productproductIInactivated by FDAbd6a592717d7…303034d00443…
2022-04-04 05:40 UTC · source 2022-04-01excluded packagepackage13925-508-20IInactivated by FDAbd6a592717d7…303034d00443…
2021-12-27 23:28 UTC · source 2021-12-27excluded productproductIInactivated by FDA8dfbde2a14a4…c9ff85d89658…
2021-12-27 23:28 UTC · source 2021-12-27excluded packagepackage13925-508-20IInactivated by FDA8dfbde2a14a4…c9ff85d89658…
2020-12-18 03:04 UTC · source 2020-12-17excluded productproductIInactivated by FDAe2bbac7714bc…27bdfed8d636…
2020-12-18 03:04 UTC · source 2020-12-17excluded packagepackage13925-508-20IInactivated by FDAe2bbac7714bc…27bdfed8d636…
2020-06-10 20:45 UTC · source 2020-06-10excluded productproductIInactivated by FDA9bebd1f3094a…5416666fcb17…
2020-06-10 20:45 UTC · source 2020-06-10excluded packagepackage13925-508-20IInactivated by FDA9bebd1f3094a…5416666fcb17…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019452-001DERMA-SMOOTHE/FSFLUOCINOLONE ACETONIDE0.01%OIL / TOPICALATRLD, RS1988-02-03
N019452-002DERMA-SMOOTHE/FSFLUOCINOLONE ACETONIDE0.01%OIL / TOPICALATRLD, RS2005-11-09
N019452-003DERMOTICFLUOCINOLONE ACETONIDE0.01%OIL/DROPS / OTICATRLD, RS2005-11-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N019452-001AT
N019452-002AT
N019452-003AT

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-035bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03d06236e962d9…
2024-10-29 15:01 UTC2024-10N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-0379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-0979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-0979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-03301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-09301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-09301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-031e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-002DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS2005-11-091e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-003DERMOTIC0.01%OIL/DROPS / OTICATRLD, RS2005-11-091e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019452-001DERMA-SMOOTHE/FS0.01%OIL / TOPICALATRLD, RS1988-02-038072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N019452-001AT1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019452-002AT1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019452-003AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-001AT131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-002AT131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019452-003AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019452-001AT16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019452-002AT16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019452-003AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-001AT1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-002AT1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019452-003AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-001AT1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-002AT1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019452-003AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-001AT103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-002AT103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019452-003AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-001AT12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-002AT12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019452-003AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-001AT15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-002AT15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019452-003AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-001AT1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-002AT1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019452-003AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019452-001AT1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019452-002AT1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019452-003AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-001AT179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-002AT179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019452-003AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-001AT1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-002AT1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019452-003AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-001AT11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-002AT11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019452-003AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019452-001AT18072bd15b7f6…

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
13925-508-202024-01-30C16284748780-19d75b9d0-259f-f424-e053-dadaa90a57ceFluocinolone Acetonide 0.01% Oil Ear Drops
13925-508-202020-01-31C16284748780-19d75b9d0-259f-f424-e053-dadaa90a57ceFluocinolone Acetonide 0.01% Oil Ear Drops

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
13925-508-20ML - Milliliter13925-508f284e36f-bf1f-4e3f-a628-c219596ffdc512013-09-04

DailyMed Socrata Ingredients#

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Derma-Smoothe/FSFLUOCINOLONE ACETONIDERoyal Pharmaceuticals, LLCbc61c619-a71c-46f5-80f1-9e9ee71134aa2026-06-09Warnings, Adverse reactionsExact identifier
application applno (NDA): 019452
application number: NDA019452
DERMA-SMOOTHE/FSFLUOCINOLONE ACETONIDERoyal Pharmaceuticals113e167a-a9fe-440e-9446-d6d87963ef462026-06-09Warnings, Adverse reactionsExact identifier
application applno (NDA): 019452
application number: NDA019452
DERMOTICFLUOCINOLONE ACETONIDERoyal Pharmaceuticalseb00f222-8105-4e05-90e8-bbd1297843642025-05-09Warnings, Adverse reactionsExact identifier
application applno (NDA): 019452
application number: NDA019452