UNBLEMISH Invisible Matte Defense

Product NDC: 14222-2131
11-digit product format: 142222131
Labeler code: 14222
Product ID: 14222-2131_e6fcc289-8076-4e3b-9eb6-0ec9b1ed4f5c
Type: HUMAN OTC DRUG
Nonproprietary name: HOMOSALATE, OCTOCRYLENE, OCTISALATE, AVOBENZONE
Dosage form: GEL
Route: TOPICAL
Labeler: Rodan & Fields
Application: M020
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-03-10
Substance: HOMOSALATE; OCTOCRYLENE; OCTISALATE; AVOBENZONE
Active strength: .1; .1; .05; .03 g/mL; g/mL; g/mL; g/mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: UNBLEMISH Invisible Matte Defense
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
HOMOSALATE	.1 g/mL
OCTOCRYLENE	.1 g/mL
OCTISALATE	.05 g/mL
AVOBENZONE	.03 g/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
V06SV4M95S	Internal UNII lookup
5A68WGF6WM	Internal UNII lookup
4X49Y0596W	Internal UNII lookup
G63QQF2NOX	Internal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
9dfe7d50-f347-4671-9657-5e4fbe42b441	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
a46239a7-5963-4008-8cbb-6b9000f497eb	Product name	1	20250721
b382b4e1-6b48-45f6-bffc-e61b00b0ce19	Product name	3	20250317
d9d61457-6a5a-41fc-b418-e5479a2904b7	Product name	2	20230303
32012d5c-25ac-49c7-9d4c-1313177fff7c	Product name	1	20230112
13e7e7e3-e885-4c79-af6d-dad1aedbb06e	Product name	1	20220128
4a7d44fe-774d-404b-aad0-8a90fe78375a	Product name	4	20211025
3f45980c-c196-47e5-0e5e-48b7c57327c5	Product name	5	20200428
d12e2d7c-bd6b-45d4-94f9-6df8e1b8b27b	Product name	3	20200203
ee5c6de5-d9cd-454f-b250-7b19e5cf2992	Product name	4	20190619
ad75fcfd-a339-42a1-9c60-43ba2c654cfa	Product name	1	20170810

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
14222-2131-1	2023-11-29	C162847	48780-1	0191ceaa-71ac-198a-e063-dbdaa90aec3e	Drug Facts
14222-2131-1	2023-07-28	C162847	48780-1	0191ceaa-71ac-198a-e063-dbdaa90aec3e	Drug Facts

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
14222-2131-1	UNBLEMISH Invisible Matte Defense	1 in 1 CARTON	GEL	1		4
14222-2131-1	UNBLEMISH Invisible Matte Defense	30 mL in 1 TUBE	GEL	30		4
14222-2131-2	UNBLEMISH Invisible Matte Defense	1 in 1 CARTON	GEL	1		4
14222-2131-2	UNBLEMISH Invisible Matte Defense	7 mL in 1 TUBE	GEL	7		4
14222-2131-4	UNBLEMISH 30-Day Regimen	15 mL in 1 TUBE	GEL	15 mL	0.1 g in 1mL	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
14222-2131	UNBLEMISH INVISIBLE MATTE DEFENSE (HOMOSALATE, OCTOCRYLENE, OCTISALATE, AVOBENZONE) GEL [RODAN & FIELDS]	4	Current NDC, Legacy NDC, 4 package rows	20231130_9dfe7d50-f347-4671-9657-5e4fbe42b441.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 82 of 354 · 7,077 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Blue Lizard Kids SPF 50	ZINC OXIDE	Crown Laboratories	9983563c-1e63-0748-e053-2a95a90a971e	2026-01-12	Warnings	Exact identifier application number: M020
Blue Lizard Baby SPF 50	ZINC OXIDE	Crown Laboratories	9948f5b8-43bd-1c99-e053-2a95a90a6121	2026-01-12	Warnings	Exact identifier application number: M020
Blue Lizard Sheer SPF 50 Sunscreen	ZINC OXIDE	Crown Laboratories	3368f1cb-c341-e886-e063-6394a90a9b7c	2026-01-12	Warnings	Exact identifier application number: M020
Blue Lizard Sport SPF 50 Sunscreen	TITANIUM DIOXIDE AND ZINC OXIDE	Crown Laboratories	2f3844d8-0367-aad9-e063-6294a90a1fce	2026-01-12	Warnings	Exact identifier application number: M020
Blue Lizard Sheer Face SPF 50 Sunscreen	TITANIUM DIOXIDE AND ZINC OXIDE	Crown Laboratories	30cd79da-2f25-a42a-e063-6394a90a8332	2026-01-12	Warnings	Exact identifier application number: M020
ACCOJE PROTECTIVE AIR-FIT MINERAL SUNSCREEN	TITAMIUN DIOXIDE, ZINC OXIDE	UCL Co., Ltd.	4837b4f6-ada9-801a-e063-6294a90a8547	2026-01-12	Warnings	Exact identifier application number: M020
Intellishade Original SPF 45	OCTINOXATE, OCTISALATE, TITANIUM DIOXIDE, ZINC OXIDE	Revision, LLC	e213a681-eb22-69c0-e053-2995a90a899e	2026-01-12	Warnings	Exact identifier application number: M020
GINZING SPF 40 ENERGY-BOOSTING TINTED MOISTURIZER BROAD SPECTRUM SPF 40 SHEER TINT RELEASE	HOMOSALATE,OCTINOXATE,OCTISALATE, AND ZINC OXIDE	ORIGINS NATURAL RESOURCES INC.	48393640-4b97-04de-e063-6294a90aa6a6	2026-01-12	Warnings	Exact identifier application number: M020
Hale and Hush Broad Spectrum SPF 30 SPF 30	ZINC OXIDE	Eclectic Solutions LLC	0530904f-b02c-d8cf-e063-6294a90aa5a7	2026-01-12	Warnings	Exact identifier application number: M020
Minori Daily Mineral Face Sunscreen Broad Spectrum SPF 30	ZINC OXIDE	Minori Inc.	1d4e2654-1638-0d01-e063-6394a90af303	2026-01-12	Warnings	Exact identifier application number: M020
LUXURY BODY RITUAL HYDRATING SPF 30	ZINC OXIDE	JANE STREET LLC	15e9d688-f226-1a19-e063-6394a90ab906	2026-01-12	Warnings	Exact identifier application number: M020
BROAD SPECTRUM SPF50 SPF 50	AVOBENZONE, HOMOSALATE OCTISALATE,	NAKED SUNDAYS PTY LTD	0426b1e9-063b-c1e6-e063-6294a90a2554	2026-01-11	Warnings	Exact identifier application number: M020
SPF30 MINERAL SUNSCREEN MOUSSE	ZINC OXIDE	Aopline Biotechnology (Guangzhou) Co., Ltd.	48031a0f-c2ed-5424-e063-6294a90ad0ff	2026-01-10	Warnings	Exact identifier application number: M020
SPF 30 MINERAL WHIPPED CREAMS SHIMMER	ZINC OXIDE	Aopline Biotechnology (Guangzhou) Co., Ltd.	48037a05-722e-4231-e063-6294a90ac51f	2026-01-10	Warnings	Exact identifier application number: M020
ODLUMIVIE Tinted Mineral Sunscreen	ZINC OXIDE,TITANIUM DIOXIDE	Guangzhou Meijiao Medical Biotechnology Co., Ltd.	480d6e65-f6dc-d2a5-e063-6294a90a24a1	2026-01-10	Warnings	Exact identifier application number: M020
Cloud Brush On Sunscreen Clear Broad Spectrum SPF 50	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	FUTURE 8 LLC	9922f132-f6a5-41ca-847a-936b20bf1716	2026-01-09	Warnings	Exact identifier application number: M020
Sunscreen Lotion118mL	ZINC OXIDE 15%, TITANIUM DIOXIDE 6%, HOMOSALATE 5%, OCTISALATE 4%	Foshan Sugar Max Cosmetics CO.,Ltd	46355437-4068-9d03-e063-6394a90ae52c	2026-01-09	Warnings	Exact identifier application number: M020
ST MORIZ SUNCARE FACE SUNSCREEN SPF30	SUNCARE FACE SUNSCREEN SPF30	Aopline Biotechnology (Guangzhou) Co., Ltd.	47f26af6-4d02-3506-e063-6294a90a0fe6	2026-01-09	Warnings	Exact identifier application number: M020
Dr. C. Tuna Sun 6 SPF Tan and Care Carrot	OCTINOXATE	Farmasi US LLC	67de9257-70f3-4444-a4a2-a8d7425fcc0e	2026-01-09	Warnings	Exact identifier application number: M020
Dr. C. Tuna Sunscreen SPF30 Broad Spectrum	AVOBENZONE, OCTINOXATE, OCTOCRYLENE, HOMOSALATE	Farmasi US LLC	d9197dce-20a3-4d10-807c-ec84ab902165	2026-01-09	Warnings	Exact identifier application number: M020

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
V06SV4M95S	HOMOSALATE	118-56-9	HOMOSALATE
5A68WGF6WM	OCTOCRYLENE	6197-30-4	OCTOCRYLENE
4X49Y0596W	OCTISALATE	118-60-5	OCTISALATE
G63QQF2NOX	AVOBENZONE	70356-09-1	AVOBENZONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
200009	benzoyl peroxide 2.5 % Topical Lotion	PSN	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 0.5 % Medicated Liquid Soap	PSN	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
200009	benzoyl peroxide 25 MG/ML Topical Lotion	SCD	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 5 MG/ML Medicated Liquid Soap	SCD	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
200009	benzoyl peroxide 2.5 % Topical Lotion	SY	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 0.5 % Foaming Cleanser	SY	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 0.5 % Mask	SY	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 0.5 % Medicated Liquid Soap	SY	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1
865105	salicylic acid 0.5 % Topical Gel Cleanser	SY	e9a52ccc-6ba0-4417-86cc-b2116a5b8d26	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
14222-2131-1	14222213101	1 TUBE in 1 CARTON (14222-2131-1) / 30 mL in 1 TUBE	1 tube	2020-03-10	0000-00-00	No	No	Current
14222-2131-2	14222213102	1 TUBE in 1 CARTON (14222-2131-2) / 7 mL in 1 TUBE	1 tube	2020-06-01		No	No	Current
14222-2131-4	14222213104	15 mL in 1 TUBE	15 ml					Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
UNBLEMISH 30-Day Regimen - Rodan & Fields	Rodan & Fields	2026-04-01	HUMAN OTC DRUG LABEL	1
Drug Facts	Rodan & Fields	2023-11-27	HUMAN OTC DRUG LABEL	4