PHARBETOL

Product NDC: 16103-350
11-digit product format: 161030350
Labeler code: 16103
Product ID: 16103-350_e22d20db-8648-409d-b8db-78c1dddfbf6a
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen 500mg
Dosage form: TABLET, COATED
Route: ORAL
Labeler: Pharbest Pharmaceuticals, Inc.
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2018-03-01
Substance: ACETAMINOPHEN
Active strength: 500 mg/1
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 45 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	16103-350-11	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	16103-350-10	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	16103-350-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	16103-350-04	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	16103-350-11	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	16103-350-10	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	16103-350-08	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	16103-350-04	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	16103-350-11	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	16103-350-10	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	16103-350-08	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	16103-350-04	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	16103-350-11	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	16103-350-10	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	16103-350-08	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	16103-350-04	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	16103-350-11	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	16103-350-10	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	16103-350-08	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	16103-350-04	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	16103-350-11	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	16103-350-10	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	16103-350-08	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	16103-350-04	`1332a3947898…`	`d4bfe170f9cd…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	16103-350-11	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	16103-350-10	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	16103-350-08	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	16103-350-04	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	16103-350-11	`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	16103-350-10	`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	16103-350-08	`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	16103-350-04	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	16103-350-11	`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	16103-350-10	`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	16103-350-08	`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	16103-350-04	`bd6a592717d7…`	`303034d00443…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: PHARBETOL
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
198440	Internal RxNorm lookup
1293942	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
27337be9-e279-460e-903e-ae4463099599	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
75d4bef7-334c-4a95-abb5-bff9def24114	Product name	2	20260112
7dea7767-9f52-b60a-5435-33cb9cc28bae	Product name	4	20250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4	Product name	7	20250116
11939cf5-0ea7-5df5-5127-00a7ce07fd7f	Product name	5	20250115
0ca83774-3f79-b837-5d6f-c210102f3bc8	Product name	6	20250114
88300afc-e1c4-ad17-c80b-4957f1b809a5	Product name	5	20250113
4eddd6ca-259a-4c6c-a3a4-2025015ce043	Product name	7	20240611
16cde546-8deb-4df2-a072-dab5566ede95	Product name	1	20231003
20ab58de-c64a-4ec2-9210-3aa3fae2b66f	Product name	1	20230808
a3631b20-02d1-41d7-8187-5e5e850b9e80	Product name	1	20230306
79e1734e-f721-4d46-978a-be382f771672	Product name	2	20230110
41b814f3-0166-1c53-c9ef-a0794c7daf9d	Product name	3	20221110
a590be26-846c-8659-a5a1-fb25907965dc	Product name	2	20221110
06cc817f-60e0-4473-8e6b-c44d11dc5af6	Product name	9	20220921
92ead9ae-674d-4eee-a492-c385d496891f	Product name	3	20220308
103b151b-b17f-42ac-8624-3ef62f5e2975	Product name	2	20200507
b8497372-efe9-9dde-fa2d-59be9761aa64	Product name	9	20200428
20c8cafe-5cfc-44f8-a9be-a664f437f780	Product name	2	20200225
3a16d77a-e865-468a-aedf-6e58913c1c21	Product name	3	20190619
2a0c98e1-033f-4e0d-a0da-b5291ffbe880	Product name	1	20190320
00d531e4-b130-8c52-eaf9-826cbb6f15dd	Product name	3	20190205
aa0f353d-f35e-62e4-4e1f-5b563f01c659	Product name	9	20190205
22d922aa-c443-d9f3-b23c-03b03a9ad31c	Product name	7	20181220
377068df-225f-7318-a910-a1987cdfa361	Product name	3	20170608
23475c0b-a5b5-4fec-b97f-acca901eae6a	Product name	1	20140718
105ef617-6fa4-6713-326f-72ec8a6b75a9	Product name	1	20140508
332e86c3-7875-ca6e-f934-2206d2b31996	Product name	1	20140508
3ed6b849-48b8-8899-c288-6eeb396123b6	Product name	1	20140508
47fd879b-91c5-e1e5-130f-29d082a871ec	Product name	1	20140508
53855190-7124-8179-f018-e792f7c27f28	Product name	1	20140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092	Product name	1	20140508
84fb0b3d-1d72-b672-bc70-2b676a23e7e0	Product name	1	20140508
96c5169b-5b9d-547d-bf22-d688d91866e4	Product name	1	20140508
b8e0daf1-fb81-290b-c0bf-873be19ef775	Product name	1	20140508
c35d1ac8-8885-2ee1-6c52-5a715b242c00	Product name	1	20140508
c8753a88-edde-8e17-a396-705537b52cee	Product name	1	20140508
cd4f9ae2-1343-ecd2-ce0f-97db0c2b51ce	Product name	1	20140508
cf3a804d-0326-aa22-0142-c184b5657d85	Product name	1	20140508
d83c592c-dd97-4cbf-36ac-13da806684bd	Product name	1	20140508
e01133ad-4dcd-c7f3-454b-2ff569ee160a	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
16103-350-04	2024-12-31	Drug Facts
16103-350-08	2024-12-31	Drug Facts
16103-350-10	2024-12-31	Drug Facts
16103-350-11	2024-12-31	Drug Facts
16103-350-04	2022-01-28	Drug Facts
16103-350-08	2022-01-28	Drug Facts
16103-350-10	2022-01-28	Drug Facts
16103-350-11	2022-01-28	Drug Facts

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
16103-350-04	PHARBETOL	1 in 1 CARTON	TABLET, COATED	1	3
16103-350-04	PHARBETOL	30 in 1 BOTTLE, PLASTIC	TABLET, COATED	30	3
16103-350-08	PHARBETOL	100 in 1 BOTTLE, PLASTIC	TABLET, COATED	100	3
16103-350-08	PHARBETOL	1 in 1 CARTON	TABLET, COATED	1	3
16103-350-10	PHARBETOL	500 in 1 BOTTLE, PLASTIC	TABLET, COATED	500	3
16103-350-11	PHARBETOL	1000 in 1 BOTTLE, PLASTIC	TABLET, COATED	1000	3

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
16103-350-04	EA - Each	16103-350	526744b9-dea5-417e-b300-418dedf58c04	1	2019-04-11
16103-350-08	EA - Each	16103-350	b5389dbb-d3cb-413e-b5e6-bf0eac6a6d0c	1	2019-04-11
16103-350-10	EA - Each	16103-350	fc23c7ec-3900-4d7f-9ada-9c394688f92c	1	2022-06-06
16103-350-11	EA - Each	16103-350	2d652227-a39c-44fe-abba-8910303a8c59	1	2019-04-11

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
16103-350	PHARBETOL (ACETAMINOPHEN 500MG) TABLET, COATED [PHARBEST PHARMACEUTICALS, INC.]	2	Current NDC, Legacy NDC, 6 package rows	20250101_27337be9-e279-460e-903e-ae4463099599.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 27 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Acetaminophen Diphenhydramine HCL	ACETAMINOPHEN DIPHENHYDRAMINE HCL	WALGREENS CO.	d92d97a8-0ee3-1206-e053-2a95a90a72a8	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	SAM'S WEST INC	0c8e7095-0806-4501-e063-6394a90a89aa	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen Diphenhydramine HCL	ACETAMINOPHEN DIPHENHYDRAMINE HCL	WALGREEN CO.	b3763182-2428-155a-e053-2995a90ab578	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	WALGREENS	e467b78e-9f23-5563-e053-2a95a90a586e	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen Diphenhydramine HCL	ACETAMINOPHEN DIPHENHYDRAMINE HCL	Walgreens	fd7c3250-35d4-494a-e053-6394a90a2db5	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	CVS PHARMACY, INC	1ddb8a2b-3081-3eda-e063-6294a90ab82b	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	CVS PHARMACY, INC	b1307d52-10e6-46e1-e053-2995a90a03b6	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	CVS PHARMACY, INC	c2c6d6a1-b492-506d-e053-2995a90aac23	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	FAMILY DOLLAR	f8383108-0970-9f1e-e053-6294a90ad38f	2025-12-19	Warnings	Exact identifier application number: M013
ACETAMINOPHEN 500 MG	ACETAMINOPHEN	NUVICARE LLC	591ee107-e953-4982-b75f-13a0afd7c4ae	2025-12-19	Warnings	Exact identifier application number: M013
Nuvicare Headache Relief	ACETAMINOPHEN, ASPIRIN, CAFFEINE	NUVICARE LLC	3ede0fb6-c089-4253-9878-2b01c39e9c87	2025-12-19	Warnings	Exact identifier application number: M013
Aspirin Low Dose	ASPIRIN	NUVICARE LLC	3a4aa3c7-b726-4303-8803-74196fa5637a	2025-12-19	Warnings	Exact identifier application number: M013
ACETAMINOPHEN 500 MG	ACETAMINOPHEN	NUVICARE LLC	95edf7bd-b6a7-4be5-9ad7-8748e7c2d06e	2025-12-19	Warnings	Exact identifier application number: M013
Pain Relief PM	ACETAMINOPHEN, DIPHENHYDRAMINE	NUVICARE LLC	32a5611b-9bf6-4850-a7ff-fa240da04f45	2025-12-19	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	BETTER LIVING BRANDS LLC.	ac0e96d0-746e-fb42-e053-2a95a90a1957	2025-12-18	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	BETTER LIVING BRANDS LLC.	ac0e5dc0-96eb-47b2-e053-2995a90add0e	2025-12-18	Warnings	Exact identifier application number: M013
Acetaminophen Diphenhydramine HCl	ACETAMINOPHEN DIPHENHYDRAMINE HCL	BETTER LIVING BRANDS LLC.	ac0f8d5c-d200-1156-e053-2a95a90aece6	2025-12-18	Warnings	Exact identifier application number: M013
Pain and Fever Childrens	ACETAMINOPHEN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	e55645ab-66f9-4160-8247-395bc5b02711	2025-12-18	Warnings	Exact identifier application number: M013
Dolex Forte	ACETAMINOPHEN, ASPIRIN, CAFFEINE	Pharmadel LLC	3c2d90fc-130d-476c-e063-6294a90a8c15	2025-12-17	Warnings	Exact identifier application number: M013
CareOne Childrens Acetaminophen	ACETAMINOPHEN	American Sales Company	07bc6632-fabb-427d-81f3-c27c54caa6a0	2025-12-17	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198440	acetaminophen 500 MG Oral Tablet	PSN	27337be9-e279-460e-903e-ae4463099599	3
1293942	Pharbetol 500 MG Oral Tablet	PSN	27337be9-e279-460e-903e-ae4463099599	3
1293942	acetaminophen 500 MG Oral Tablet [Pharbetol]	SBD	27337be9-e279-460e-903e-ae4463099599	3
198440	acetaminophen 500 MG Oral Tablet	SCD	27337be9-e279-460e-903e-ae4463099599	3
198440	APAP 500 MG Oral Tablet	SY	27337be9-e279-460e-903e-ae4463099599	3
1293942	APAP 500 MG Oral Tablet [Pharbetol]	SY	27337be9-e279-460e-903e-ae4463099599	3
1293942	Pharbetol 500 MG Oral Tablet	SY	27337be9-e279-460e-903e-ae4463099599	3
198440	acetaminophen 500 MG Oral Tablet	PSN	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
1293942	Pharbetol 500 MG Oral Tablet	PSN	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
1293942	acetaminophen 500 MG Oral Tablet [Pharbetol]	SBD	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
198440	acetaminophen 500 MG Oral Tablet	SCD	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
198440	APAP 500 MG Oral Tablet	SY	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
1293942	APAP 500 MG Oral Tablet [Pharbetol]	SY	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1
1293942	Pharbetol 500 MG Oral Tablet	SY	622b3838-9ecf-481d-bf4b-4ca0ffa77492	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
16103-350-04	16103035004	1 BOTTLE, PLASTIC in 1 CARTON (16103-350-04) / 30 TABLET, COATED in 1 BOTTLE, PLASTIC	2018-03-01	0000-00-00	No	No	Current
16103-350-08	16103035008	1 BOTTLE, PLASTIC in 1 CARTON (16103-350-08) / 100 TABLET, COATED in 1 BOTTLE, PLASTIC	2018-03-01	0000-00-00	No	No	Current
16103-350-10	16103035010	500 TABLET, COATED in 1 BOTTLE, PLASTIC (16103-350-10)	2018-03-01	0000-00-00	No	No	Current
16103-350-11	16103035011	1000 TABLET, COATED in 1 BOTTLE, PLASTIC (16103-350-11)	2018-03-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Drug Facts	Pharbest Pharmaceuticals, Inc.	2025-12-24	HUMAN OTC DRUG LABEL	3
Drug Facts	A-S Medication Solutions	2019-06-24	HUMAN OTC DRUG LABEL	1