Temsirolimus

Product NDC
16729-223
11-digit product format
167290223
Labeler code
16729
Product ID
16729-223_116814b6-e438-8a45-e063-6394a90a9fad
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
temsirolimus
Dosage form
KIT
Labeler
Accord Healthcare Inc.
Application
ANDA203153
Marketing category
ANDA
Marketing start
2018-08-13
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203153-001TEMSIROLIMUSTEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A203153-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-3087673890dc5c…
2021-03-12 10:30 UTC2021-03A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-303f01610625f2…
2019-09-15 20:21 UTC2019-09A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30b00525d2431f…
2019-07-19 19:46 UTC2019-07A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-303f0d92c62455…
2023-05-13 08:27 UTC2023-05A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30053a50430f4f…
2023-01-26 05:58 UTC2023-01A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A203153-001TEMSIROLIMUS25MG/ML (25MG/ML)SOLUTION / INTRAVENOUSAP2018-07-30cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A203153-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203153-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203153-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203153-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203153-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203153-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203153-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203153-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203153-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203153-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203153-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203153-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203153-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203153-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203153-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203153-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203153-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203153-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203153-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203153-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A203153-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A203153-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A203153-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A203153-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A203153-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A203153-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A203153-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A203153-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A203153-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A203153-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A203153-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A203153-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A203153-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A203153-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A203153-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A203153-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A203153-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A203153-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A203153-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A203153-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Temsirolimus
Listing expiration
2026-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
722289Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ae8d2354-7ddb-41b8-9d55-77c84782b18fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3d47a74f-57c0-aa00-f0cb-1e9b88cf3b18Product name320200129

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16729-221-30Temsirolimus1 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION, CONCENTRATE1 mL25 mg in 1mL3
16729-223-61Temsirolimus1 in 1 KITKIT13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16729-223-61ML - Milliliter16729-2237f72f60d-7824-44a6-a75a-14429e39a2e512018-10-11

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16729-223TEMSIROLIMUS KIT [ACCORD HEALTHCARE INC.]3Current NDC, Legacy NDC, 2 package rows20240216_ae8d2354-7ddb-41b8-9d55-77c84782b18f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TemsirolimusTEMSIROLIMUSAccord Healthcare Inc.ae8d2354-7ddb-41b8-9d55-77c84782b18f2024-02-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203153
application number: ANDA203153
ndc (product): 16729-223

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
722289temsirolimus 25 MG/ML in 1.2 ML InjectionPSNae8d2354-7ddb-41b8-9d55-77c84782b18f3
7222891.2 ML temsirolimus 25 MG/ML InjectionSCDae8d2354-7ddb-41b8-9d55-77c84782b18f3
722289temsirolimus 25 MG/ML per 1.2 ML InjectionSYae8d2354-7ddb-41b8-9d55-77c84782b18f3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
16729-221-30167290221301 mL in 1 VIAL, SINGLE-DOSE1 mlHistorical
16729-223-61167290223611 KIT in 1 KIT (16729-223-61) * 1 mL in 1 VIAL, SINGLE-DOSE (16729-221-30) * 1.8 mL in 1 VIAL, SINGLE-DOSE (16729-222-30) 1 kit2018-08-130000-00-00NoNoCurrent