Busulfan

Product NDC
16729-351
11-digit product format
167290351
Labeler code
16729
Product ID
16729-351_0e2ef789-efb4-8395-e063-6294a90a9145
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
busulfan
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Accord Healthcare, Inc
Application
ANDA210148
Marketing category
ANDA
Marketing start
2019-07-22
Substance
BUSULFAN
Active strength
6 mg/mL
Pharmacologic classes
Alkylating Activity [MoA], Alkylating Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A210148-001BUSULFANBUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A210148-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-2274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-2287673890dc5c…
2021-03-12 10:30 UTC2021-03A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-223f01610625f2…
2019-09-15 20:21 UTC2019-09A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22b00525d2431f…
2019-07-19 19:46 UTC2019-07A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-229b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-223f0d92c62455…
2023-05-13 08:27 UTC2023-05A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22053a50430f4f…
2023-01-26 05:58 UTC2023-01A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-223bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-223a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210148-001BUSULFAN6MG/MLINJECTABLE / INJECTIONAP2019-02-22cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A210148-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210148-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A210148-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210148-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210148-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210148-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210148-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210148-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210148-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210148-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210148-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210148-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210148-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210148-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210148-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210148-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210148-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A210148-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A210148-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210148-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210148-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A210148-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210148-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210148-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A210148-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A210148-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A210148-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210148-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210148-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210148-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210148-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210148-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210148-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210148-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A210148-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A210148-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210148-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210148-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210148-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210148-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Busulfan
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUSULFAN6 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
G1LN9045DKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
253113Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fe0ddd44-ef02-4827-b164-7fcbb45bcc1bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
5cd205af-1b5a-44f8-d007-fc9f5ee3cd5dProduct name920210518
0bcaeed6-5866-1c9f-3423-7db0fa4d0985Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
16729-351-03Busulfan10 mL in 1 VIAL, SINGLE-DOSEINJECTION104
16729-351-92Busulfan8 in 1 CARTONINJECTION84

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
16729-351-03ML - Milliliter16729-351d1d1f14b-f386-4517-9ad4-69cd6e3b2a0112019-08-06
16729-351-92ML - Milliliter16729-351cad3c358-5cfc-45fd-9bf0-003d4e557c9412019-07-02

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
16729-351BUSULFAN INJECTION [ACCORD HEALTHCARE, INC]4Current NDC, Legacy NDC, 2 package rows20240106_fe0ddd44-ef02-4827-b164-7fcbb45bcc1b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BusulfanBUSULFANAccord Healthcare, Incfe0ddd44-ef02-4827-b164-7fcbb45bcc1b2024-01-05Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210148
application number: ANDA210148
ndc (product): 16729-351

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
253113busulfan 60 MG in 10 ML InjectionPSNfe0ddd44-ef02-4827-b164-7fcbb45bcc1b4
25311310 ML busulfan 6 MG/ML InjectionSCDfe0ddd44-ef02-4827-b164-7fcbb45bcc1b4
253113busulfan 60 MG per 10 ML InjectionSYfe0ddd44-ef02-4827-b164-7fcbb45bcc1b4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
16729-351-031672903510310 mL in 1 VIAL, SINGLE-DOSE10 mlHistorical
16729-351-92167290351928 VIAL, SINGLE-DOSE in 1 CARTON (16729-351-92) / 10 mL in 1 VIAL, SINGLE-DOSE (16729-351-03) 2019-07-220000-00-00NoNoCurrent