Lactulose

Product NDC
18124-002
11-digit product format
181240002
Labeler code
18124
Product ID
18124-002_d95ab755-1c2e-4124-8ed7-075936257c25
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lactulose
Dosage form
SOLUTION
Route
ORAL; RECTAL
Labeler
Fresenius Kabi Austria GmbH
Application
ANDA090502
Marketing category
ANDA
Marketing start
2012-12-10
Substance
LACTULOSE
Active strength
10 g/15mL
Pharmacologic classes
Acidifying Activity [MoA], Osmotic Activity [MoA], Osmotic Laxative [EPC], Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A090502-001LACTULOSELACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A090502-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAA2012-01-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAA2012-01-253f01610625f2…
2019-09-15 20:21 UTC2019-09A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAA2012-01-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAA2012-01-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A090502-001LACTULOSE10GM/15MLSOLUTION / ORAL, RECTALAARS2012-01-25cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A090502-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A090502-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A090502-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A090502-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A090502-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A090502-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A090502-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A090502-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A090502-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A090502-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A090502-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A090502-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A090502-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A090502-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A090502-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A090502-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A090502-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A090502-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A090502-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A090502-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A090502-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A090502-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A090502-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A090502-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A090502-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A090502-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A090502-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A090502-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A090502-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A090502-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A090502-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A090502-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A090502-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A090502-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A090502-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A090502-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A090502-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A090502-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A090502-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A090502-001AA1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Lactulose
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LACTULOSE10 g/15mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9U7D5QH5AEInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
391937Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a89835c9-8ce5-4627-8d7d-70ff175b2e07Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
13620a32-e3b4-4aad-8280-283dce30ddffProduct name120260105
27883b46-af31-44b0-b4ce-e6b4f6d825a7Product name420250812
c1a80c95-0e51-52a0-75fa-75808f51ded8Product name220150421

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
18124-002-16Lactulose473 mL in 1 BOTTLESOLUTION4735

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
18124-002LACTULOSE (LACTULOSE) SOLUTION [FRESENIUS KABI AUSTRIA GMBH]5Current NDC, Legacy NDC, 1 package rows20221112_a89835c9-8ce5-4627-8d7d-70ff175b2e07.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EnuloseLACTULOSEBryant Ranch Prepackfa3aae7c-6f98-4fbb-85dc-32affe9874d52024-12-18Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090502
application number: ANDA090502
LactuloseLACTULOSEFresenius Kabi Austria GmbHa89835c9-8ce5-4627-8d7d-70ff175b2e072022-11-09Adverse reactionsExact identifier
application applno (ANDA): 090502
application number: ANDA090502
ndc (product): 18124-002
EnuloseLACTULOSEActavis Pharma, Inc.00c42c5c-d19e-4130-aa08-a8bbd47d3e5b2022-06-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 090502
application number: ANDA090502

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
391937lactulose 10 GM in 15 mL Oral SolutionPSNa89835c9-8ce5-4627-8d7d-70ff175b2e075
391937lactulose 667 MG/ML Oral SolutionSCDa89835c9-8ce5-4627-8d7d-70ff175b2e075
391937lactulose 10 GM per 15 ML Oral SolutionSYa89835c9-8ce5-4627-8d7d-70ff175b2e075
391937lactulose 20 GM per 30 ML Oral SolutionSYa89835c9-8ce5-4627-8d7d-70ff175b2e075

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
18124-002-1618124000216473 mL in 1 BOTTLE (18124-002-16) 473 ml2012-12-100000-00-00NoNoCurrent