Signature Care First Aid Antibiotic

Product NDC: 21130-559
11-digit product format: 211300559
Labeler code: 21130
Product ID: 21130-559_8504465f-cb55-4a7b-bb82-bfca8641b91d
Type: HUMAN OTC DRUG
Nonproprietary name: Neomycin, Polymyxin B, Pramoxine HCl
Dosage form: CREAM
Route: TOPICAL
Labeler: Safeway
Application: M004
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2015-11-10
Substance: NEOMYCIN SULFATE; PRAMOXINE HYDROCHLORIDE; POLYMYXIN B SULFATE
Active strength: 3.5; 10; 10000 mg/g; mg/g; [USP'U]/g
Pharmacologic classes: Aminoglycoside Antibacterial [EPC], Aminoglycosides [CS], Polymyxin-class Antibacterial [EPC], Polymyxins [CS]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Signature Care First Aid Antibiotic
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
NEOMYCIN SULFATE	3.5 mg/g
PRAMOXINE HYDROCHLORIDE	10 mg/g
POLYMYXIN B SULFATE	10000 [USP'U]/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
057Y626693	Internal UNII lookup
88AYB867L5	Internal UNII lookup
19371312D4	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1359360	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
99e684e6-f435-feb8-d2bb-3a546f1cb768	Product name	2	20161117
25340b3b-3e4c-4ff8-abf6-3e62ec46bd0c	Product name	1	20160603
58f3f9b7-3b9b-a9c1-1c9f-18ac777192b8	Product name	1	20140508
a7051cba-790b-a699-81f8-dbbbdbd9b5ac	Product name	1	20140508
b045ad64-0f28-9a02-2f9b-b34d94fb2278	Product name	1	20140508
b6082387-f592-1148-0844-bd068fd213fb	Product name	1	20140508
da108d9e-edc8-17a3-8c28-3251c6a8accc	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
21130-559-58	Signature Care First Aid Antibiotic	14 g in 1 TUBE	CREAM	14		4
21130-559-58	Signature Care First Aid Antibiotic	1 in 1 CARTON	CREAM	1		4

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
NEOMYCIN SULFATE	ACTIVE INGREDIENT	057Y626693	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
POLYMYXIN B SULFATE	ACTIVE INGREDIENT	19371312D4	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
PRAMOXINE HYDROCHLORIDE	ACTIVE INGREDIENT	88AYB867L5	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
NEOMYCIN	ACTIVE MOIETY	I16QD7X297	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
POLYMYXIN B	ACTIVE MOIETY	J2VZ07J96K	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
PRAMOXINE	ACTIVE MOIETY	068X84E056	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
MINERAL OIL	INACTIVE INGREDIENT	T5L8T28FGP	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
PETROLATUM	INACTIVE INGREDIENT	4T6H12BN9U	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
POLOXAMER 188	INACTIVE INGREDIENT	LQA7B6G8JG	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
21130-559	SIGNATURE CARE FIRST AID ANTIBIOTIC (NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL) CREAM [SAFEWAY]	4	Current NDC, Legacy NDC, 2 package rows	20240927_78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 2 of 22 · 424 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
First Aid Antibiotic and Burn Relief	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B, PRAMOXINE HYDROCHLORIDE	Amazon.com Services LLC	3459a453-0a94-4122-adad-bb120daecd9e	2026-08-18	Warnings	Exact identifier application number: M004
Dealmed Triple Antibiotic	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE	Dealmed Medical Supplies, LLC.	b3f1e834-4e8f-49f6-af0d-38097ae4f928	2026-08-13	Warnings	Exact identifier application number: M004
Dealmed Bacitracin	BACITRACIN ZINC	Dealmed Medical Supplies, LLC.	26f282b5-b3af-4049-93f6-659071be721d	2026-08-12	Warnings	Exact identifier application number: M004
triple antibiotic pain relief	BACITRACIN, NEOMYCIN, POLYMYXIN B, PRAMOXINE HCL	Walgreen Company	f0fa2822-02a2-49e5-ad47-aa7e9cc2da71	2026-08-11	Warnings	Exact identifier application number: M004
Bacitracin Zinc	BACITRACIN ZINC	A-S Medication Solutions	9fcda25b-3940-4028-a8ee-6e6c6e4b2a53	2026-08-07	Warnings	Exact identifier application number: M004
Triple Antibiotic	BACITRACIN ZINC, NEOMYCIN SULFATE, AND POLYMYXIN B SULFATE	Salado Sales, Inc	52e275d3-88c9-47f1-8dcf-68445c7be4a7	2026-08-05	Warnings	Exact identifier application number: M004
Wound Wash Antiseptic Saline with Benzalkonium Chloride	WOUND WASH ANTISEPTIC SALINE WITH BENZALKONIUM CHLORIDE	NeilMed Pharmaceuticals, Inc.	55a1fc63-2527-4033-e054-00144ff8d46c	2026-08-05	Warnings	Exact identifier application number: M004
ProcureTriple Antibiotic Triple Antibiotic	BACITRACIN ZINC NEOMYCIN SULFATE POLYMYXIN B	TWIN MED, LLC	71592776-407b-489c-8cdb-8c0573d844f8	2026-08-03	Warnings	Exact identifier application number: M004
procureFirst Aid Antibio First Aid Antibiotic	BACITRACIN	TWIN MED, LLC	8d19e931-99c4-47b8-b7ec-94c16535166f	2026-08-03	Warnings	Exact identifier application number: M004
TRIPLE ANTIBIOTIC	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE	Vive Health LLC	236c62bf-3de0-0b3e-e063-6394a90ad6c6	2026-07-21	Warnings	Exact identifier application number: M004
TRIPLE ANTIBIOTIC	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE	Vive Health LLC	21b38b00-1e64-83d8-e063-6294a90a07bd	2026-07-21	Warnings	Exact identifier application number: M004
DERMFREE Triple Antibiotic	TRIPLE ANTIBIOTIC	Jiangxi Yudexi Pharmaceutical Co., LTD	4a5a5603-3478-5f7a-e063-6294a90acc40	2026-07-21	Warnings	Exact identifier application number: M004
Bacitracin	BACITRACIN ZINC	Preferred Pharmaceuticals Inc.	e094566b-3b80-45ac-be73-54c798bbb763	2026-07-15	Warnings	Exact identifier application number: M004
CAREALL Bacitracin	BACITRACIN ZINC	New World Imports, Inc	560ba2ca-ad0f-9202-e063-6294a90aaefd	2026-07-14	Warnings	Exact identifier application number: M004
CareALL Triple Antibiotic	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE	New World Imports, Inc	561bf89c-ca78-d7e4-e063-6394a90a983f	2026-07-14	Warnings	Exact identifier application number: M004
Good Sense First Aid Antibiotic	BACITRACIN ZINC, NEOMYCIN, POLYMYXIN B	L. Perrigo Company	3eadd35c-3df2-4e46-b76d-a6e537895917	2026-07-10	Warnings	Exact identifier application number: M004
CareALL Triple Antibiotic plus Pain Relief	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, PRAMOXINE HCL	New World Imports, Inc	561c1e51-19f4-90ce-e063-6294a90a5f9b	2026-07-08	Warnings	Exact identifier application number: M004
Ever Ready First Aid Triple Antibiotic	BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE	EVER READY FIRST AID	ee1ad6d7-e9c1-2b20-e053-2995a90a3366	2026-07-03	Warnings	Exact identifier application number: M004
Single Antibiotic with bacitracin	BACITRACIN ZINC	Safetec of America	4ae9a105-e3f9-4015-8844-085e0b34cdb6	2026-06-25	Warnings	Exact identifier application number: M004
Antibacterial Hand Wipes (0.13% Benzalkonium Chloride)	BENZALKONIUM CHLORIDE	Eleeo Brands LLC	551baf59-39b9-e994-e063-6294a90a65e6	2026-06-25	Warnings	Exact identifier application number: M004

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
057Y626693	NEOMYCIN SULFATE	1405-10-3	NEOMYCIN SULFATE
88AYB867L5	PRAMOXINE HYDROCHLORIDE	637-58-1	PRAMOXINE HYDROCHLORIDE
19371312D4	POLYMYXIN B SULFATE	1405-20-5	POLYMYXIN B SULFATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1359360	neomycin 3.5 MG / polymyxin B 10,000 UNT / pramoxine HCl 10 MG per GM Topical Cream	PSN	78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	4
1359360	neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML / pramoxine hydrochloride 10 MG/ML Topical Cream	SCD	78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	4
1359360	neomycin (as neomycin sulfate) 0.35 % / polymyxin B (as polymyxin B sulfate) 10,000 UNT/ML / pramoxine (as pramoxine HCl) 1 % Topical Cream	SY	78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	4
1359360	neomycin 0.35 % / polymyxin B 10,000 UNT/ML / pramoxine HCl 1 % Topical Cream	SY	78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	4
1359360	neomycin 3.5 MG / polymyxin B 10,000 UNT / pramoxine HCl 10 MG per GM Topical Cream	SY	78ecfb28-f4c4-4f70-90c9-d6d7bf920fb5	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
21130-559-58	21130055958	1 TUBE in 1 CARTON (21130-559-58) / 14 g in 1 TUBE	1 tube	2015-11-10	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Better Living Brands LLC First Aid Antibiotic Cream + Pain Relief Drug Facts	Safeway	2024-09-26	HUMAN OTC DRUG LABEL	4