Allergy Relief

Product NDC: 21130-596
11-digit product format: 211300596
Labeler code: 21130
Product ID: 21130-596_39e2d06e-0ff4-c74a-e063-6394a90a15f7
Type: HUMAN OTC DRUG
Nonproprietary name: Diphenhydramine HCl
Dosage form: TABLET
Route: ORAL
Labeler: BETTER LIVING BRANDS LLC.
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2023-05-31
Substance: DIPHENHYDRAMINE HYDROCHLORIDE
Active strength: 25 mg/1
Pharmacologic classes: Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Allergy Relief
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1049630	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
f29da4ca-443d-7035-e053-2a95a90acab8	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
21130-596-01	Allergy Relief	1 in 1 CARTON	TABLET	1	4
21130-596-01	Allergy Relief	100 in 1 BOTTLE	TABLET	100	4
21130-596-20	Allergy Relief	1 in 1 CARTON	TABLET	1	4
21130-596-20	Allergy Relief	200 in 1 BOTTLE	TABLET	200	4
21130-596-35	Allergy Relief	365 in 1 BOTTLE	TABLET	365	4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
21130-596	ALLERGY RELIEF (DIPHENHYDRAMINE HCL) TABLET [BETTER LIVING BRANDS LLC.]	3	Current NDC, 5 package rows	20231020_f29da4ca-443d-7035-e053-2a95a90acab8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 129 of 180 · 3,583 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Foster and Thrive Chest Congestion Relief DM DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Strategic Sourcing Services LLC	5372f764-985e-4a42-bc97-cb0dc90fcd9c	2024-12-18	Warnings	Exact identifier application number: M012
TopCare Chest Congestion and Cough Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	TOPCO ASSOCIATES LLC	5a2d0464-038d-4c3f-b39e-ee9984fb383e	2024-12-18	Warnings	Exact identifier application number: M012
Always Save Chest Congestion Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Valu Merch	a72b6a97-f97f-44bb-8d55-ac48b8ba45c5	2024-12-18	Warnings	Exact identifier application number: M012
Harris Teeter Allergy Relief	DIPHENHYDRAMINE HYDROCHLORIDE	Harris Teeter	4ebe1d94-bb15-4250-a4c2-8cd45743c7dd	2024-12-18	Warnings	Exact identifier application number: M012
Care One Chest Congestion Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	RETAIL BUSINESS SERVICES , LLC	f6657dee-9f32-45b1-8e44-1ad67a4a68bd	2024-12-18	Warnings	Exact identifier application number: M012
Childrens Metapp Daytime	BROMPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL	Guardian Drug Company	40565500-944b-47f2-8563-5df05469e418	2024-12-18	Warnings	Exact identifier application number: M012
CVS Chest Congestion Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	CVS Pharmacy, Inc.	884abed2-e355-4134-92f1-591f3a18f71d	2024-12-18	Warnings	Exact identifier application number: M012
CVS Health Chest Congestion Relief PE	GUAIFENESIN/PHENYLEPHRINE	CVS Pharmacy, Inc.	a49020e8-739e-47ec-8141-e866479a3ab3	2024-12-18	Warnings	Exact identifier application number: M012
Family Wellness Chest Congestion Relief DM DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Family Dollar Services Inc	8aee8108-a4e0-4956-8e37-6b3b1c5dc683	2024-12-18	Warnings	Exact identifier application number: M012
TopCare Chest Congestion Relief	GUAIFENESIN	TOPCO ASSOCIATES LLC	b8339617-17ce-4ad7-af38-399ecc74d864	2024-12-18	Warnings	Exact identifier application number: M012
Kroger Allergy Relief	DIPHENHYDRAMINE HYDROCHLORIDE	THE KROGER CO	976bfdcf-2110-486c-aa6e-cd2067334cdc	2024-12-18	Warnings	Exact identifier application number: M012
Good Neighbor Pharmacy Mucus Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	AmerisourceBergen Drug Corp	79cefd46-bd19-4a1d-9cb1-e85ff0f12494	2024-12-18	Warnings	Exact identifier application number: M012
Leader Chest Congestion Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Cardinal Health	8397e1b9-e83e-4c6a-b858-1663c2365840	2024-12-18	Warnings	Exact identifier application number: M012
GNP Mucus Relief PE	GUAIFENESIN/PHENYLEPHRINE	AmerisourceBergen Drug Corp	63932e68-b09d-4500-bc1d-cfb2c267df1c	2024-12-18	Warnings	Exact identifier application number: M012
Meijer Chest Congestion Relief	GUAIFENESIN	Meijer Distribution Inc.	ae02e0bd-d9e7-495f-b01f-b135b96934a0	2024-12-18	Warnings	Exact identifier application number: M012
Topcare Chest Congestion and Sinus Congestion Relief PE	GUAIFENESIN/PHENYLEPHRINE	TOPCO ASSOCIATES LLC	b6c0362f-86ca-4f08-ba53-800c6df2c025	2024-12-18	Warnings	Exact identifier application number: M012
Sunmark Chest Congestion Relief DM DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Strategic Sourcing Services LLC	10cad9a7-1223-470c-9027-807891217d40	2024-12-18	Warnings	Exact identifier application number: M012
Kroger Mucus Relief	GUAIFENESIN	THE KROGER CO	2b7ad844-4c30-4c0e-aa8e-d7aa6fe4af4e	2024-12-18	Warnings	Exact identifier application number: M012
Quality Choice Mucus Relief	GUAIFENESIN	Chain Drug Marketing Association	41f88b43-3e0a-4650-b167-a72afe6177e8	2024-12-18	Warnings	Exact identifier application number: M012
Rugby Chest Congestion Relief DM	DEXTROMETHORPHAN HYDROBROMIDE / GUAIFENESIN	Rugby Laboratories	5da36516-9f94-49cb-9421-0c310abcd116	2024-12-18	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1049630	diphenhydrAMINE HCl 25 MG Oral Tablet	PSN	f29da4ca-443d-7035-e053-2a95a90acab8	4
1049630	diphenhydramine hydrochloride 25 MG Oral Tablet	SCD	f29da4ca-443d-7035-e053-2a95a90acab8	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
21130-596-01	21130059601	1 BOTTLE in 1 CARTON (21130-596-01) / 100 TABLET in 1 BOTTLE	1 bottle	2023-05-31	No	No	Current
21130-596-20	21130059620	1 BOTTLE in 1 CARTON (21130-596-20) / 200 TABLET in 1 BOTTLE	1 bottle	2023-05-31	No	No	Current
21130-596-35	21130059635	365 TABLET in 1 BOTTLE (21130-596-35)	365 tablet	2023-07-27	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
160R_Albertsons_21130-596_Diphenhydramine HCl 25 mg Tablets	BETTER LIVING BRANDS LLC. \| TIME CAP LABORATORIES, INC. \| MARKSANS PHARMA LIMITED	2025-07-14	HUMAN OTC DRUG LABEL	4