SIGNATURE CARE ACNE TREATMENT

Product NDC: 21130-722
11-digit product format: 211300722
Labeler code: 21130
Product ID: 21130-722_0a25883f-99a5-2915-e063-6294a90aedc3
Type: HUMAN OTC DRUG
Nonproprietary name: SALICYLIC ACID
Dosage form: LIQUID
Route: TOPICAL
Labeler: SAFEWAY, INC.
Application: M020
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2012-03-26
Substance: SALICYLIC ACID
Active strength: 20 mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: SIGNATURE CARE ACNE TREATMENT
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
SALICYLIC ACID	20 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
O414PZ4LPZ	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
562600	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
a60134d0-f788-90e8-e053-2a95a90acbde	Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
21130-722-48	SIGNATURE CARE ACNE TREATMENT	258 mL in 1 BOTTLE, PUMP	LIQUID	258		3
21130-722-77	SIGNATURE CARE ACNE TREATMENT	177 mL in 1 BOTTLE, PUMP	LIQUID	177		3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
21130-722	SIGNATURE CARE ACNE TREATMENT (SALICYLIC ACID) LIQUID [SAFEWAY, INC.]	3	Current NDC, Legacy NDC, 2 package rows	20231115_a60134d0-f788-90e8-e053-2a95a90acbde.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 189 of 346 · 6,912 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
CYZONE CY PLAY CREAMY LIP BALM HIDRATANTE EN BARRA PARA LABIOS 24H FPS 12 FUCHSIA CREAMY	OCTINOXATE, ZINC OXIDE	BEL STAR S A	ea39a1c0-6b12-77ba-e053-2995a90a7314	2025-08-21	Warnings	Exact identifier application number: M020
Neutrogena Clear Face Breakout Free Oil Free Sunscreen Broad Spectrum SPF 30	AVOBENZONE, HOMOSALATE, OCTISALATE, AND OCTOCRYLENE	Kenvue Brands LLC	cd211d06-b91e-44b1-99fe-fa0794f10221	2025-08-21	Warnings	Exact identifier application number: M020
Sun Bum Sunscreen Lip Balm Broad Spectrum SPF 30 Kiwi	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	3cd51497-693e-bf79-e063-6394a90a5e48	2025-08-21	Warnings	Exact identifier application number: M020
LBEL SOLUTIONS PRO-NUDE SKIN ULTRA-LIGHT SERUM FOUNDATION WITH NIACINAMIDE SPF 20 CHAMPAGNE 170N	OCTINOXATE, ZINC OXIDE	BEL STAR S.A.	2f769ed5-0176-8c80-e063-6394a90a92c6	2025-08-21	Warnings	Exact identifier application number: M020
Sun Bum 30 Premium Moisturizing Sunscreen	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	21caf385-f11b-146a-e063-6294a90aa851	2025-08-21	Warnings	Exact identifier application number: M020
Sun Bum 50 Premium Moisturizing Sunscreen	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	21cb8652-c6d0-0a77-e063-6294a90a6e1e	2025-08-21	Warnings	Exact identifier application number: M020
Sun Bum Signature High Performance Mineral Sunscreen Face Stick 30	ZINC OXIDE	Sun Bum, LLC	3ce81478-196e-d87b-e063-6294a90afd58	2025-08-21	Warnings	Exact identifier application number: M020
Premium Moisturizing Sunscreen Broad Spectrum SPF 30	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	33164cea-e31e-9fcc-e063-6294a90a307e	2025-08-21	Warnings	Exact identifier application number: M020
PHOFAY Matte Sunscreen Liquid Foundation SPF 30 5	ENSULIZOLE,HOMOSALATE,OCTINOXATE,TITANIUM DIOXIDE	Longway Technology(Guangzhou) Co., Ltd.	3ceb3368-439c-9f6c-e063-6294a90a98ba	2025-08-21	Warnings	Exact identifier application number: M020
PHOFAY Matte Sunscreen Liquid Foundation SPF 30 2	ENSULIZOLE ,HOMOSALATE ,OCTINOXATE,TITANIUM DIOXIDE	Longway Technology(Guangzhou) Co., Ltd.	3cc8b151-c07d-7473-e063-6294a90a1cc7	2025-08-20	Warnings	Exact identifier application number: M020
Olay Complete Hydrating with Sunscreen Broad Spectrum SPF 15	AVOBENZONE, HOMOSALATE, OCTISALATE, AND OCTOCRYLENE	The Procter & Gamble Manufacturing Company	3ccd2703-c410-74b7-e063-6294a90a7f88	2025-08-20	Warnings	Exact identifier application number: M020
SEYE	ZINC OXIDE AND TITANIUM DIOXIDE CREAM	Guangzhou Seye Biomedical Technology Co., Ltd.	3cce91b1-311b-4c95-e063-6294a90a2d7a	2025-08-20	Warnings	Exact identifier application number: M020
Sun Bum Day Tripper - SPF 30 Moisturizing Sunscreen 3 OZ	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	3ccfb90a-5976-4b38-e063-6294a90a123a	2025-08-20	Warnings	Exact identifier application number: M020
Sun Bum Day Tripper - SPF 30 Sunscreen Lip Balm (Coconut) 0.15 OZ	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	3cd3ce69-becc-41b7-e063-6394a90a2782	2025-08-20	Warnings	Exact identifier application number: M020
Lip Therapy Soothe and Protect Lip Treatment Broad Spectrum SPF 30	AVOBENZONE, HOMOSALATE, OCTISALATE, AND OCTOCRYLENE	Obagi Cosmeceuticals LLC	4838679b-f510-440b-8670-a10c05ebed9b	2025-08-19	Warnings	Exact identifier application number: M020
Sun Bum Signature High Performance Mineral Sunscreen Broad Spectrum SPF 50 New	ZINC OXIDE	Sun Bum, LLC	3b8e1d73-b023-cfbd-e063-6294a90ae29d	2025-08-19	Warnings	Exact identifier application number: M020
Olay Total Effects Moisturizer with Sunscreen Broad Spectrum SPF 15 Fragrance-Free	AVOBENZONE, HOMOSALATE, OCTISALATE, AND OCTOCRYLENE	The Procter & Gamble Manufacturing Company	8de31db2-46cf-7178-e053-2995a90a5024	2025-08-19	Warnings	Exact identifier application number: M020
Lip Balm - Variety Pack (Target) - Banana (4)	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE	Sun Bum, LLC	3cbcae23-9b38-edaa-e063-6294a90a2e8f	2025-08-19	Warnings	Exact identifier application number: M020
Sun Bum Signature High Performance Mineral Sunscreen Lip Balm 30	ZINC OXIDE	Sun Bum, LLC	3cbeb4ce-6d7c-387c-e063-6394a90af790	2025-08-19	Warnings	Exact identifier application number: M020
Olay Total Effects Moisturizer Broad Spectrum SPF 30	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE, AND OXYBENZONE	The Procter & Gamble Manufacturing Company	8de52cb2-b4d2-1e0d-e053-2995a90a5aca	2025-08-19	Warnings	Exact identifier application number: M020

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
O414PZ4LPZ	SALICYLIC ACID	69-72-7	SALICYLIC ACID

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
562600	salicylic acid 2 % Medicated Liquid Soap	PSN	a60134d0-f788-90e8-e053-2a95a90acbde	3
562600	salicylic acid 20 MG/ML Medicated Liquid Soap	SCD	a60134d0-f788-90e8-e053-2a95a90acbde	3
562600	salicylic acid 2 % Facial Cleanser Toner	SY	a60134d0-f788-90e8-e053-2a95a90acbde	3
562600	salicylic acid 2 % Facial Scrub	SY	a60134d0-f788-90e8-e053-2a95a90acbde	3
562600	salicylic acid 2 % Medicated Liquid Soap	SY	a60134d0-f788-90e8-e053-2a95a90acbde	3

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
21130-722-48	21130072248	258 mL in 1 BOTTLE, PUMP (21130-722-48)	258 ml	2023-08-10		No	No	Current
21130-722-77	21130072277	177 mL in 1 BOTTLE, PUMP (21130-722-77)	177 ml	2012-03-26	0000-00-00	No	No	Current