Besivance

Product NDC: 24208-446
11-digit product format: 242080446
Labeler code: 24208
Product ID: 24208-446_1c4756f2-d92f-af5d-e063-6294a90a9a49
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Besifloxacin
Dosage form: SUSPENSION
Route: OPHTHALMIC
Labeler: Bausch & Lomb Incorporated
Application: NDA022308
Marketing category: NDA
Marketing start: 2009-05-28
Substance: BESIFLOXACIN
Active strength: 6 mg/mL
Pharmacologic classes: Quinolone Antimicrobial [EPC], Quinolones [CS]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N022308-001	BESIVANCE	BESIFLOXACIN HYDROCHLORIDE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC		RLD, RS	2009-05-28

Orange Book patents#

Current patent rows page 1 of 1 · 4 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N022308-001	8937062	2029-11-13	U-80		2015-02-03
N022308-001	8604020	2030-03-12		Drug product	2013-12-16
N022308-001	8415342	2030-11-07	U-80		2013-04-11
N022308-001	8481526	2031-01-09		Drug substance	2013-07-19

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	RLD / RS	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N022308-001	BESIVANCE	EQ 0.6% BASE	SUSPENSION/DROPS / OPHTHALMIC	RLD, RS	2009-05-28	`f41ea6bd6efb…`

Observed Orange Book patent history#

Patent history page 1 of 5 · 185 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-09-14 22:38:34	2026-08	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022308-001	8937062	2029-11-13	U-80		2015-02-03	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022308-001	8604020	2030-03-12		Drug product	2013-12-16	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022308-001	8415342	2030-11-07	U-80		2013-04-11	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N022308-001	8481526	2031-01-09		Drug substance	2013-07-19	`5bbf6a4d5a75…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Besivance
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
BESIFLOXACIN	6 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
BFE2NBZ7NX	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
850305	Internal RxNorm lookup
850309	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
a3e6d688-7e5e-4ca3-b27e-79756c322a32	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
24208-446-02	2020-08-13	These highlights do not include all the information needed to use BESIVANCE safely and effectively. See full prescribing information for BESIVANCE. BESIVANCE ® (besifloxacin ophthalmic suspension), for topical ophthalmic use Initial U.S. Approval: 2009
24208-446-05	2020-08-13	These highlights do not include all the information needed to use BESIVANCE safely and effectively. See full prescribing information for BESIVANCE. BESIVANCE ® (besifloxacin ophthalmic suspension), for topical ophthalmic use Initial U.S. Approval: 2009
24208-446-02	2020-07-22	These highlights do not include all the information needed to use BESIVANCE safely and effectively. See full prescribing information for BESIVANCE. BESIVANCE ® (besifloxacin ophthalmic suspension), for topical ophthalmic use Initial U.S. Approval: 2009
24208-446-05	2020-07-22	These highlights do not include all the information needed to use BESIVANCE safely and effectively. See full prescribing information for BESIVANCE. BESIVANCE ® (besifloxacin ophthalmic suspension), for topical ophthalmic use Initial U.S. Approval: 2009

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
24208-446-02	Besivance	2 mL in 1 BOTTLE, DROPPER	SUSPENSION	2	20
24208-446-02	Besivance	1 in 1 CARTON	SUSPENSION	1	20
24208-446-05	Besivance	1 in 1 CARTON	SUSPENSION	1	20
24208-446-05	Besivance	5 mL in 1 BOTTLE, DROPPER	SUSPENSION	5	20

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
24208-446-05	ML - Milliliter	24208-446	ecbec0c9-ddaa-4fc7-9cfc-9df37715b0dc	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
BESIFLOXACIN	ACTIVE INGREDIENT	BFE2NBZ7NX	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
BESIFLOXACIN	ACTIVE MOIETY	BFE2NBZ7NX	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
BENZALKONIUM CHLORIDE	INACTIVE INGREDIENT	F5UM2KM3W7	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
MANNITOL	INACTIVE INGREDIENT	3OWL53L36A	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
POLOXAMER 407	INACTIVE INGREDIENT	TUF2IVW3M2	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
POLYCARBOPHIL	INACTIVE INGREDIENT	W25LM17A4W	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
WATER	INACTIVE INGREDIENT	059QF0KO0R	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	9
BESIFLOXACIN	ACTIVE INGREDIENT	BFE2NBZ7NX	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
BESIFLOXACIN	ACTIVE MOIETY	BFE2NBZ7NX	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
BENZALKONIUM CHLORIDE	INACTIVE INGREDIENT	F5UM2KM3W7	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
MANNITOL	INACTIVE INGREDIENT	3OWL53L36A	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
POLOXAMER 407	INACTIVE INGREDIENT	TUF2IVW3M2	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
POLYCARBOPHIL	INACTIVE INGREDIENT	W25LM17A4W	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	BESIVANCE (BESIFLOXACIN) SUSPENSION [PHYSICIANS TOTAL CARE, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
24208-446	BESIVANCE (BESIFLOXACIN) SUSPENSION [BAUSCH & LOMB INCORPORATED]	20	Current NDC, Legacy NDC, 4 package rows	20240704_a3e6d688-7e5e-4ca3-b27e-79756c322a32.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Besivance	BESIFLOXACIN	Sportpharm LLC	f312ddb2-3173-4c2c-bf1b-4ade8fb75d94	2026-07-28	Warnings, Adverse reactions	Exact identifier application applno (NDA): 022308 application number: NDA022308
Besivance	BESIFLOXACIN	Sportpharm LLC	80bf4981-4f86-4d25-83a5-7d5dfe0b22e0	2026-07-23	Warnings, Adverse reactions	Exact identifier application applno (NDA): 022308 application number: NDA022308
Besivance	BESIFLOXACIN	Bausch & Lomb Americas Inc.	ff971287-5610-4f15-8392-fc974e6ff646	2026-01-12	Warnings, Adverse reactions	Exact identifier application applno (NDA): 022308 application number: NDA022308
Besivance	BESIFLOXACIN	Bausch & Lomb Incorporated	a3e6d688-7e5e-4ca3-b27e-79756c322a32	2024-07-03	Warnings, Adverse reactions	Exact identifier application applno (NDA): 022308 application number: NDA022308 ndc (product): 24208-446

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
BFE2NBZ7NX	BESIFLOXACIN	141388-76-3	BESIFLOXACIN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
850305	besifloxacin 0.6 % Ophthalmic Suspension	PSN	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850309	Besivance 0.6 % Ophthalmic Suspension	PSN	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850309	besifloxacin 6 MG/ML Ophthalmic Suspension [Besivance]	SBD	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850305	besifloxacin 6 MG/ML Ophthalmic Suspension	SCD	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850305	besifloxacin 0.6 % Ophthalmic Suspension	SY	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850309	Besivance 0.6 % Ophthalmic Suspension	SY	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850309	Besivance 6 MG/ML Ophthalmic Suspension	SY	a3e6d688-7e5e-4ca3-b27e-79756c322a32	20
850305	besifloxacin 0.6 % Ophthalmic Suspension	PSN	c326263e-4b55-41b6-b862-c970668669ec	1
850309	Besivance 0.6 % Ophthalmic Suspension	PSN	c326263e-4b55-41b6-b862-c970668669ec	1
850309	besifloxacin 6 MG/ML Ophthalmic Suspension [Besivance]	SBD	c326263e-4b55-41b6-b862-c970668669ec	1
850305	besifloxacin 6 MG/ML Ophthalmic Suspension	SCD	c326263e-4b55-41b6-b862-c970668669ec	1
850305	besifloxacin 0.6 % Ophthalmic Suspension	SY	c326263e-4b55-41b6-b862-c970668669ec	1
850309	Besivance 0.6 % Ophthalmic Suspension	SY	c326263e-4b55-41b6-b862-c970668669ec	1
850309	Besivance 6 MG/ML Ophthalmic Suspension	SY	c326263e-4b55-41b6-b862-c970668669ec	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
24208-446-02	24208044602	1 BOTTLE, DROPPER in 1 CARTON (24208-446-02) / 2 mL in 1 BOTTLE, DROPPER	2009-05-28	0000-00-00	No	No	Current
24208-446-05	24208044605	1 BOTTLE, DROPPER in 1 CARTON (24208-446-05) / 5 mL in 1 BOTTLE, DROPPER	2009-05-28	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Besivance	Sportpharm LLC	2026-07-23	HUMAN PRESCRIPTION DRUG LABEL	1
Besivance	Bausch & Lomb Incorporated	2024-07-03	HUMAN PRESCRIPTION DRUG LABEL	20
BESIVANCE	A-S Medication Solutions	2023-07-25	HUMAN PRESCRIPTION DRUG LABEL	13
Besivance	Physicians Total Care, Inc.	2009-04-01	HUMAN PRESCRIPTION DRUG LABEL	1