Advanced Eye Relief/ Redness Maximum Relief

Product NDC: 24208-450
11-digit product format: 242080450
Labeler code: 24208
Product ID: 24208-450_22f543dc-1475-ff56-e063-6394a90a867b
Type: HUMAN OTC DRUG
Nonproprietary name: Naphazoline Hydrochloride and Hypromellose
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Bausch & Lomb Incorporated
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2010-09-02
Substance: HYPROMELLOSE, UNSPECIFIED; NAPHAZOLINE HYDROCHLORIDE
Active strength: 5; .3 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	24208-450	24208-450-90	D	Discontinued by firm		2026-10-20

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source date	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Advanced Eye Relief/ Redness Maximum Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
HYPROMELLOSE, UNSPECIFIED	5 mg/mL
NAPHAZOLINE HYDROCHLORIDE	.3 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3NXW29V3WO	Internal UNII lookup
MZ1131787D	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1046654	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3c11285a-7e86-4b47-b1ee-e7d59858087d	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e18001c8-33ae-5f66-9cdc-a39724bd4573	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
24208-450-15	Advanced Eye Relief/ Redness Maximum Relief	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	11
24208-450-15	Advanced Eye Relief/ Redness Maximum Relief	1 in 1 CARTON	SOLUTION/ DROPS	1	11
24208-450-90	Advanced Eye Relief/ Redness Maximum Relief	2 in 1 CARTON	SOLUTION/ DROPS	2	11
24208-450-90	Advanced Eye Relief/ Redness Maximum Relief	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	11

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYPROMELLOSES	ACTIVE INGREDIENT	3NXW29V3WO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
NAPHAZOLINE HYDROCHLORIDE	ACTIVE INGREDIENT	MZ1131787D	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
HYPROMELLOSES	ACTIVE MOIETY	3NXW29V3WO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
NAPHAZOLINE	ACTIVE MOIETY	H231GF11BV	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
BENZALKONIUM CHLORIDE	INACTIVE INGREDIENT	F5UM2KM3W7	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
BORIC ACID	INACTIVE INGREDIENT	R57ZHV85D4	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
HYDROCHLORIC ACID	INACTIVE INGREDIENT	QTT17582CB	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM BORATE	INACTIVE INGREDIENT	91MBZ8H3QO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
WATER	INACTIVE INGREDIENT	059QF0KO0R	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
24208-450	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	11	Current NDC, Legacy NDC, 4 package rows	20240927_3c11285a-7e86-4b47-b1ee-e7d59858087d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 23 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Signature Care Eye Drops Advanced Relief	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Better Living Brands LLC	5d7228ce-f108-4cc2-9aec-8b4548c3a155	2023-12-20	Warnings	Exact identifier application number: M018
Target Eye Drops Maximum Redness Relief Eye	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	Target Corporation	1b26cd3b-4a05-4623-b320-01f22b3106ff	2023-12-20	Warnings	Exact identifier application number: M018
Kroger High Performance Lubricant Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Kroger	d2aa8963-1922-02f3-e053-2a95a90a7d93	2023-12-20	Warnings	Exact identifier application number: M018
Kroger Eye Drops Seasonal Relief	TETRAHYDROZOLINE HCL, ZINC SULFATE	Kroger	f6829be4-e3b7-7ff2-e053-2995a90a80fc	2023-12-20	Warnings	Exact identifier application number: M018
Rite Aid Multi-Symptom Relief Eye Drops	POLYETHYLENE GLYCOL 400, TETRAHYDROZOLINE HCL, ZINC SULFATE	Rite Aid Corporation	efa7d208-9d42-13c7-e053-2a95a90a11b3	2023-12-20	Warnings	Exact identifier application number: M018
Signature Care Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Better Living Brands LLC	ea358e01-f03e-454b-bae1-6c83da44c369	2023-12-20	Warnings	Exact identifier application number: M018
TopCare Health Original Eye Drops	TETRAHYDROZOLINE HCL	Topco Associates LLC	9c61a56a-c1a9-2846-e053-2995a90a755b	2023-12-20	Warnings	Exact identifier application number: M018
Signature Care Eye Drops A.C.	TETRAHYDROZOLINE HCL, ZINC SULFATE	Better Living Brands LLC	f685aca4-93d0-26d9-e053-2995a90a6e51	2023-12-20	Warnings	Exact identifier application number: M018
Kroger Lubricant Eye	CARBOXYMETHYLCELLULOSE SODIUM	The Kroger Co.	046f4ebc-d8f9-4755-b6ba-790fe86f3128	2023-12-20	Warnings	Exact identifier application number: M018
Kroger Eye Drops Advanced Relief	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HYDROCHLORIDE	Kroger Company	f7ad77fc-d890-25b9-e053-6394a90a2b12	2023-12-20	Warnings	Exact identifier application number: M018
TopCare Health Dry Eye Relief Eye Drops	GLYCERIN, HYPROMELLOSE, POLYETHYLENE GLYCOL 400	Topco Associates LLC	9c617e34-fc66-1a5b-e053-2995a90ace2c	2023-12-20	Warnings	Exact identifier application number: M018
Equaline Advanced Relief Eye Drops	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HYDROCHLORIDE	United Natural Foods, Inc.	f7602789-179a-edfc-e053-6294a90a0844	2023-12-20	Warnings	Exact identifier application number: M018
Topcare Health Ultra Itch Relief Astringent Eye Drops	TETRAHYDROZOLINE HCL, ZINC SULFATE	Topco Associates LLC	9c617e34-fc64-1a5b-e053-2995a90ace2c	2023-12-20	Warnings	Exact identifier application number: M018
Topcare Health Artificial Tears	POLYVINYL ALCOHOL, POVIDONE	Topco Associates LLC	9c614c0e-5862-682f-e053-2a95a90abc09	2023-12-20	Warnings	Exact identifier application number: M018
Topcare Health Lubricant Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Topco Assoc LLC	9c6284f9-00bb-37b5-e053-2a95a90ae2ee	2023-12-20	Warnings	Exact identifier application number: M018
HEB Dry Eye Eye Drops	GLYCERIN, HYPROMELLOSE, POLYETHYLENE GLYCOL 400	HEB	f80023cf-8e42-780a-e053-6294a90a66cd	2023-12-20	Warnings	Exact identifier application number: M018
TopCare Health Advanced Moisturizing Plus Redness Relief	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Topco Associates LLC	9c6193a6-d822-1b27-e053-2995a90ab3cf	2023-12-20	Warnings	Exact identifier application number: M018
Topcare Maximum Redness Relief Eye Drops	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	Topco Assoc LLC	9c6193a6-d824-1b27-e053-2995a90ab3cf	2023-12-20	Warnings	Exact identifier application number: M018
HEB Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	HEB	5d522e4d-d647-486f-a947-25c14b1417fa	2023-12-20	Warnings	Exact identifier application number: M018
HEB A.C. Eye Drops	TETRAHYDROZOLINE HCL, ZINC SULFATE	HEB Grocery Company., LP	f680a8c1-dc91-7a52-e053-2a95a90a571e	2023-12-20	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
3NXW29V3WO	HYPROMELLOSE, UNSPECIFIED	9004-65-3	HYPROMELLOSE, UNSPECIFIED
MZ1131787D	NAPHAZOLINE HYDROCHLORIDE	550-99-2	NAPHAZOLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1046654	hypromellose 0.5 % / naphazoline HCl 0.03 % Ophthalmic Solution	PSN	3c11285a-7e86-4b47-b1ee-e7d59858087d	11
1046654	hypromellose 5 MG/ML / naphazoline hydrochloride 0.3 MG/ML Ophthalmic Solution	SCD	3c11285a-7e86-4b47-b1ee-e7d59858087d	11
1046654	hypromellose 0.5 % / naphazoline hydrochloride 0.03 % Ophthalmic Solution	SY	3c11285a-7e86-4b47-b1ee-e7d59858087d	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
24208-450-15	24208045015	1 BOTTLE, DROPPER in 1 CARTON (24208-450-15) / 15 mL in 1 BOTTLE, DROPPER	2010-09-02	0000-00-00	No	No	Current
24208-450-90	24208045090	2 BOTTLE, DROPPER in 1 CARTON (24208-450-90) > 15 mL in 1 BOTTLE, DROPPER	2015-05-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Drug Facts	Bausch & Lomb Incorporated	2024-09-25	HUMAN OTC DRUG LABEL	11
Drug Facts	Preferred Pharmaceuticals Inc.	2017-06-07	HUMAN OTC DRUG LABEL	1