Xlear Nasal Decongestant

Product NDC: 27017-018
11-digit product format: 270170018
Labeler code: 27017
Product ID: 27017-018_42f23852-91f2-0dea-e063-6394a90a30fe
Type: HUMAN OTC DRUG
Nonproprietary name: Nasal Spray
Dosage form: LIQUID
Route: NASAL
Labeler: Xlear Inc.
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2019-03-12
Substance: OXYMETAZOLINE HYDROCHLORIDE
Active strength: .0005 g/g
Pharmacologic classes: Imidazolines [CS], Increased Sympathetic Activity [PE], Vasoconstriction [PE], Vasoconstrictor [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Xlear Nasal Decongestant
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
OXYMETAZOLINE HYDROCHLORIDE	.0005 g/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K89MJ0S5VY	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1000990	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1c1db71a-47d0-42ac-8cbe-95e76dca185f	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e67be450-f8e4-4bc1-88bd-1259d379f55f	Product name	1	20210127
c53f3286-4062-4cf5-8355-399519c639a6	Product name	1	20170424
a993dfc5-f219-4460-bde6-30dd724d9ef0	Product name	1	20160818

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
27017-018-01	Xlear Nasal Decongestant	1 g in 1 BOTTLE, SPRAY	LIQUID	1		4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
27017-018	XLEAR NASAL DECONGESTANT (NASAL SPRAY) LIQUID [XLEAR INC.]	3	Current NDC, Legacy NDC, 1 package rows	20240126_1c1db71a-47d0-42ac-8cbe-95e76dca185f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 139 of 178 · 3,551 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Poly-Vent IR	GUAIFENESIN AND PSEUDOEPHEDRINE HCL	Poly Pharmaceuticals, Inc.	ce0d8c45-446a-4df4-a36b-5000ba69d30d	2024-11-09	Warnings	Exact identifier application number: M012
basic care tussin dm	DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN	Amazon.com Services LLC	306d5914-03ed-410a-9345-c54ba604e991	2024-11-09	Warnings	Exact identifier application number: M012
care one nasal original	OXYMETAZOLINE HYDROCHLORIDE	American Sales Company	a0c35e06-c9e9-438e-8224-d4760b6e2aff	2024-11-09	Warnings	Exact identifier application number: M012
adult tussin dm	DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN	Walgreen Company	34174507-cf2e-4ed4-85ec-f915d4b910df	2024-11-08	Warnings	Exact identifier application number: M012
Childrens Benadryl Chewables	DIPHENHYDRAMINE HYDROCHLORIDE	Kenvue Brands LLC	b08f71d8-a06c-41ba-8ed1-fbc41dbc1919	2024-11-08	Warnings	Exact identifier application number: M012
SUDAFED PE SINUS CONGESTION	DIPHENHYDRAMINE HYDROCHLORIDE AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	a38fdfb8-db89-487f-9b68-aa9152b91f5f	2024-11-08	Warnings	Exact identifier application number: M012
SUDAFED Sinus Congestion	PSEUDOEPHEDRINE HYDROCHLORIDE	Kenvue Brands LLC	c05d7e27-6821-468f-b27d-9c0b02a07b0f	2024-11-08	Warnings	Exact identifier application number: M012
Benadryl	DIPHENHYDRAMINE HYDROCHLORIDE	Kenvue Brands LLC	2884d2dc-2d4a-4ca6-ab73-688a80b428eb	2024-11-08	Warnings	Exact identifier application number: M012
Extra Strength TYLENOL Cold plus Flu Multi-Action Day/Night	ACETAMINOPHEN, PSEUDOEPHEDRINE HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE, AND CHLORPHENIRAMINE MALEATE	Kenvue Brands LLC	712ba011-79aa-469b-9f0f-04a0b4b705bd	2024-11-08	Warnings	Exact identifier application number: M012
SUDAFED PE Pressure Plus Pain	ACETAMINOPHEN AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	8538c291-9ce9-4866-b268-f4cbdb52f5bd	2024-11-08	Warnings	Exact identifier application number: M012
Childrens Sudafed Nasal Decongestant	PSEUDOEPHEDRINE HYDROCHLORIDE	Kenvue Brands LLC	52e9307b-ad38-4f65-bb2f-4fa262e82010	2024-11-08	Warnings	Exact identifier application number: M012
Benadryl Allergy Plus Congestion	DIPHENHYDRAMINE HYDROCHLORIDE AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	685b51d3-cc25-47b2-ac8a-368924f43137	2024-11-08	Warnings	Exact identifier application number: M012
Sudafed PE Sinus Pressure Plus Pain	ACETAMINOPHEN AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	60183922-bfd3-4377-884a-51b2f0a4c93a	2024-11-08	Warnings	Exact identifier application number: M012
Sudafed PE Sinus Congestion	PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	2ca08917-1a75-4365-8520-c083e6a4225a	2024-11-08	Warnings	Exact identifier application number: M012
SUDAFED PE Head Congestion Plus Mucus	ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	f0739186-41b9-4761-adf7-08101b30a18e	2024-11-08	Warnings	Exact identifier application number: M012
SUDAFED PE Head Congestion Plus Flu Severe	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	1e528f78-0ced-4a06-935a-84056c921727	2024-11-08	Warnings	Exact identifier application number: M012
TYLENOL Cold Plus Flu Severe and TYLENOL COLD MAX CoPack	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	657a1e59-104c-4152-b2c9-00a8b82dc78e	2024-11-08	Warnings	Exact identifier application number: M012
Tylenol Cold plus Flu Severe and Tylenol Cold Max	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	47c61858-72ce-409b-a3af-a63620cf7d13	2024-11-08	Warnings	Exact identifier application number: M012
Childrens Benadryl Allergy Plus Congestion	DIPHENHYDRAMINE HYDROCHLORIDE AND PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	b8b75904-3806-4258-89c1-d6ff486ed41c	2024-11-08	Warnings	Exact identifier application number: M012
Tylenol Cold Plus Flu Severe Day and Tylenol Cold Plus Flu Plus Cough Night 3-Pack	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, AND GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE	Kenvue Brands LLC	464de5de-0e7a-41d6-875f-dd0e5fe7893c	2024-11-08	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
K89MJ0S5VY	OXYMETAZOLINE HYDROCHLORIDE	2315-02-8	OXYMETAZOLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1000990	oxymetazoline HCl 0.05 % Nasal Spray	PSN	1c1db71a-47d0-42ac-8cbe-95e76dca185f	4
1000990	oxymetazoline hydrochloride 0.5 MG/ML Nasal Spray	SCD	1c1db71a-47d0-42ac-8cbe-95e76dca185f	4
1000990	oxymetazoline hydrochloride 0.05 % Nasal Spray	SY	1c1db71a-47d0-42ac-8cbe-95e76dca185f	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
27017-018-01	27017001801	1 g in 1 BOTTLE, SPRAY (27017-018-01)	1 g	2019-03-12	0000-00-00	No	No	Current