Opana

Product NDC
35356-825
11-digit product format
353560825
Labeler code
35356
Product ID
35356-825_c0d14e51-b521-45ca-af3f-667af6f27f23
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
oxymorphone hydrochloride
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
Lake Erie Medical DBA Quality Care Products LLC
Application
NDA201655
Marketing category
NDA
Marketing start
2012-03-20
Marketing end
0000-00-00
Substance
OXYMORPHONE HYDROCHLORIDE
Active strength
20 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA],Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2019-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct35356-825DDiscontinued by firm2026-08-10
excluded packagepackage35356-82535356-825-30DDiscontinued by firm2026-08-10
excluded packagepackage35356-82535356-825-60DDiscontinued by firm2026-08-10

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 36 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage35356-825-60d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage35356-825-30d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage35356-825-60f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage35356-825-30f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage35356-825-602ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage35356-825-302ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage35356-825-60a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage35356-825-30a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage35356-825-60cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage35356-825-30cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage35356-825-60cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage35356-825-30cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage35356-825-60302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage35356-825-30302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage35356-825-60ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage35356-825-30ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage35356-825-600efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage35356-825-300efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage35356-825-60ad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage35356-825-30ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage35356-825-60367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage35356-825-30367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage35356-825-60557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage35356-825-30557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 7 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N201655-001OPANA EROXYMORPHONE HYDROCHLORIDE5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-002OPANA EROXYMORPHONE HYDROCHLORIDE7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-003OPANA EROXYMORPHONE HYDROCHLORIDE10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-004OPANA EROXYMORPHONE HYDROCHLORIDE15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-005OPANA EROXYMORPHONE HYDROCHLORIDE20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-006OPANA EROXYMORPHONE HYDROCHLORIDE30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09
N201655-007OPANA EROXYMORPHONE HYDROCHLORIDE40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09

Orange Book patents#

Current patent rows page 1 of 1 · 21 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N201655-00188087372027-06-21U-15982014-11-07
N201655-00178514822029-07-10Drug substance2012-03-22
N201655-00188717792029-11-22Drug substance2014-11-07
N201655-00288087372027-06-21U-15982014-11-07
N201655-00278514822029-07-10Drug substance
N201655-00288717792029-11-22Drug substance2014-11-07
N201655-00388087372027-06-21U-15982014-11-07
N201655-00378514822029-07-10Drug substance
N201655-00388717792029-11-22Drug substance2014-11-07
N201655-00488087372027-06-21U-15982014-11-07
N201655-00478514822029-07-10Drug substance
N201655-00488717792029-11-22Drug substance2014-11-07
N201655-00588087372027-06-21U-15982014-11-07
N201655-00578514822029-07-10Drug substance
N201655-00588717792029-11-22Drug substance2014-11-07
N201655-00688087372027-06-21U-15982014-11-07
N201655-00678514822029-07-10Drug substance
N201655-00688717792029-11-22Drug substance2014-11-07
N201655-00788087372027-06-21U-15982014-11-07
N201655-00778514822029-07-10Drug substance
N201655-00788717792029-11-22Drug substance2014-11-07

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 8 · 287 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-006OPANA ER30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-007OPANA ER40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-006OPANA ER30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-007OPANA ER40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-006OPANA ER30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N201655-007OPANA ER40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-006OPANA ER30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N201655-007OPANA ER40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-006OPANA ER30MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N201655-007OPANA ER40MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201655-001OPANA ER5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201655-002OPANA ER7.5MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201655-003OPANA ER10MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201655-004OPANA ER15MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N201655-005OPANA ER20MGTABLET, EXTENDED RELEASE / ORALRLD2011-12-0903ed91905a0d…

Observed Orange Book patent history#

Patent history page 1 of 52 · 2,051 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N201655-00188087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00178514822029-07-10Drug substance2012-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00188717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00288087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00278514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00288717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00388087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00378514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00388717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00488087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00478514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00488717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00588087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00578514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00588717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00688087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00678514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00688717792029-11-22Drug substance2014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00788087372027-06-21U-15982014-11-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00778514822029-07-10Drug substance011fe1cb6892…
2026-02-19 14:30 UTC2026-02N201655-00788717792029-11-22Drug substance2014-11-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00181927222025-09-15Drug product2012-06-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00188087372027-06-21U-15982014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00178514822029-07-10Drug substance2012-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00188717792029-11-22Drug substance2014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00281927222025-09-15Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00288087372027-06-21U-15982014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00278514822029-07-10Drug substance31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00288717792029-11-22Drug substance2014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00381927222025-09-15Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00388087372027-06-21U-15982014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00378514822029-07-10Drug substance31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00388717792029-11-22Drug substance2014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00481927222025-09-15Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00488087372027-06-21U-15982014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00478514822029-07-10Drug substance31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00488717792029-11-22Drug substance2014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00581927222025-09-15Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00588087372027-06-21U-15982014-11-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N201655-00578514822029-07-10Drug substance31067a03dcf5…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
35356-825-30EA - Each35356-825f87abf60-81b9-40e7-8ed0-712a2ca5017812013-02-13
35356-825-60EA - Each35356-82598dff5ef-6011-4f5b-894b-8c85c5fe30fa12013-02-13