Head and Shoulders

Product NDC: 37000-078
Requested package NDC: 37000-078-83
11-digit product format: 370000078
Labeler code: 37000
Product ID: 37000-078_4cda90a8-cfc7-00fd-e063-6294a90aa27d
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: LOTION/SHAMPOO
Route: TOPICAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2013-09-01
Substance: PYRITHIONE ZINC
Active strength: 1 g/100mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Head and Shoulders
Brand name suffix: Green Apple 2in1
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	1 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup
1043244	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
c036c9a6-6507-4037-b97b-1b015dd950c1	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
37000-078-01	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-01	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-11	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-11	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-12	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-12	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-25	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-25	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-40	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-40	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-70	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-70	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-95	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-95	2022-04-11	Head and Shoulders ® Green Apple 2in1
37000-078-01	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-01	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-11	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-11	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-12	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-12	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-25	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-25	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-40	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-40	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-70	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-70	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-95	2021-01-29	Head and Shoulders ® Green Apple 2in1
37000-078-95	2021-01-29	Head and Shoulders ® Green Apple 2in1

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
37000-078-01	Head and ShouldersGreen Apple 2in1	1000 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1000	13
37000-078-02	Head and ShouldersGreen Apple 2in1	950 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	950	13
37000-078-02	Head and ShouldersGreen Apple 2in1	2 in 1 CELLO PACK	LOTION/SHAMPOO	2	13
37000-078-11	Head and ShouldersGreen Apple 2in1	1180 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1180	13
37000-078-12	Head and ShouldersGreen Apple 2in1	1280 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1280	13
37000-078-25	Head and ShouldersGreen Apple 2in1	250 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	250	13
37000-078-37	Head and ShouldersGreen Apple 2in1	370 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	370	13
37000-078-40	Head and ShouldersGreen Apple 2in1	400 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	400	13
37000-078-61	Head and ShouldersGreen Apple 2in1	613 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	613	13
37000-078-70	Head and ShouldersGreen Apple 2in1	700 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	700	13
37000-078-83	Head and ShouldersGreen Apple 2in1	835 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	835	13
37000-078-95	Head and ShouldersGreen Apple 2in1	950 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	950	13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Pyrithione Zinc	ACTIVE INGREDIENT	R953O2RHZ5	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
Pyrithione Zinc	ACTIVE MOIETY	R953O2RHZ5	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
cocamidopropyl betaine	INACTIVE INGREDIENT	5OCF3O11KX	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
dimethicone	INACTIVE INGREDIENT	92RU3N3Y1O	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
FD&C blue no. 1	INACTIVE INGREDIENT	H3R47K3TBD	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
FD&C yellow no. 5	INACTIVE INGREDIENT	I753WB2F1M	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
glycol distearate	INACTIVE INGREDIENT	13W7MDN21W	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
magnesium carbonate hydroxide	INACTIVE INGREDIENT	YQO029V1L4	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
methylchloroisothiazolinone	INACTIVE INGREDIENT	DEL7T5QRPN	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
methylisothiazolinone	INACTIVE INGREDIENT	229D0E1QFA	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
sodium benzoate	INACTIVE INGREDIENT	OJ245FE5EU	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
sodium laureth-3 sulfate	INACTIVE INGREDIENT	BPV390UAP0	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
sodium xylenesulfonate	INACTIVE INGREDIENT	G4LZF950UR	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
water	INACTIVE INGREDIENT	059QF0KO0R	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3
zinc carbonate	INACTIVE INGREDIENT	EQR32Y7H0M	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [PROCTER & GAMBLE MANUFACTURING CO.]	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
37000-078	HEAD AND SHOULDERS GREEN APPLE 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	12	Current NDC, Legacy NDC, 12 package rows	20241020_c036c9a6-6507-4037-b97b-1b015dd950c1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 2 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
apgwgzminoxidil2%	MINOXIDIL	Guangdong Jiaoyu Biotechnology Co., Ltd	5957c990-e274-6278-e063-6394a90af2b7	2026-08-18	Warnings	Exact identifier application number: M032
EVERYDAY CLEAN DANDRUFF	PYRITHIONE ZINC	Universal Distribution Center LLC	3983b688-28ae-462e-8686-6cf2f2c1cca4	2026-08-18	Warnings	Exact identifier application number: M032
Prosoria Psoriasis Treatment	SALICYLIC ACID	Nuvothera, Inc.	378311aa-95f7-4c69-bc00-e688468262bd	2026-08-18	Warnings	Exact identifier application number: M032
RoyceDerm Seborrheic Dermatitis and Psoriasis Treatment cream	SALICYLIC ACID 3%	RoyceDerm LLC	496e178b-e29b-071e-e063-6394a90aa018	2026-08-13	Warnings	Exact identifier application number: M032
RoyceDerm Seborrheic Dermatitis and Psoriasis shampoo.	SALICYLIC ACID 3%	RoyceDerm LLC	4995ce33-e231-8f86-e063-6394a90af486	2026-08-13	Warnings	Exact identifier application number: M032
Rida Hair Research Institute RHRI Neoketramin Antifungal Yeast Relief	PYRITHIONE ZINC	Rida LLC	d1e4dee7-5962-4ec1-ab99-9d547077b2f2	2026-08-05	Warnings	Exact identifier application number: M032
Rida Hair Research Institute RHRI Neoketramin Antifungal Yeast Relief Treatment	SALICYLIC ACID	Rida LLC	6226ce12-432f-402e-bda7-a5ca96f0b838	2026-08-05	Warnings	Exact identifier application number: M032
JOHNSON FOAM	MINOXIDIL	JOHNSON BIOPHARMACEUTICAL INC.	1d44a75c-c940-680c-e063-6394a90a5839	2026-08-02	Warnings	Exact identifier application number: M032
EVERYDAY CLEAN DANDRUFF	PYRITHIONE ZINC	NINGBO LIYUAN DAILY CHEMICAL PRODUCTS CO., LTD.	5a03d4bb-72e6-cc9f-e063-6394a90ae19f	2026-08-01	Warnings	Exact identifier application number: M032
TEA TREE Oil DANDRUFF	PYRITHIONE ZINC	NINGBO LIYUAN DAILY CHEMICAL PRODUCTS CO., LTD.	5a0505a6-77ca-c56e-e063-6394a90aea6f	2026-08-01	Warnings	Exact identifier application number: M032
ITCHY SCALP RELIEF DANDRUFF	PYRITHIONE ZINC	NINGBO LIYUAN DAILY CHEMICAL PRODUCTS CO., LTD.	5a0521cd-2b9e-e02c-e063-6394a90a5f02	2026-08-01	Warnings	Exact identifier application number: M032
SMOOTH AND SOFT DANDRUFF	PYRITHIONE ZINC	NINGBO LIYUAN DAILY CHEMICAL PRODUCTS CO., LTD.	5a054179-b0d7-3a0f-e063-6294a90a6209	2026-08-01	Warnings	Exact identifier application number: M032
FOLKI COSMETIC Psoriasis Cream	SALICYLIC ACID 3% PSORIASIS CREAM	Wenzhou Yuyuan Pharmaceutical Co., Ltd.	575786e0-21b8-ad9d-e063-6394a90ad0d4	2026-07-24	Warnings	Exact identifier application number: M032
RoyceDerm Psoriasis Scalp .spray.	SALICYLIC ACID 2%	RoyceDerm LLC	57425b1a-4cf3-b133-e063-6394a90a84f5	2026-07-23	Warnings	Exact identifier application number: M032
RoyceDerm Psoriasis Scalp .Shampoo.	SALICYLIC ACID 3%	RoyceDerm LLC	5743f813-57f7-f544-e063-6294a90ad3b8	2026-07-23	Warnings	Exact identifier application number: M032
Yodo Salil	OINTMENT	Laboratorio Neo Farmaco del Ecuador Neofarmaco Cia. LTDA.	56812625-7eab-6a25-e063-6294a90a23fe	2026-07-20	Warnings	Exact identifier application number: M032
Pureskin Seborrheic Dermatitis and Psoriasis Cream	SEBORRHEIC DERMATITIS PSORIASIS CREAM	BENLONG HALL LLC	36086f7f-8536-417f-a302-37f78288489e	2026-07-20	Warnings	Exact identifier application number: M032
5%MINOXIDIL TOPICAL FOAM	MINOXIDIL	Veloce Trading Co., Limited	56f87881-653f-17e6-e063-6294a90a6787	2026-07-19	Warnings	Exact identifier application number: M032
ProBliva Psoriasis Shampoo.	SALICYLIC ACID 3%	CAVTECH HOLDING LLC	563e75f9-a1e2-2796-e063-6294a90aedb4	2026-07-10	Warnings	Exact identifier application number: M032
ProBliva Anti Dandruff Shampoo.	SELENIUM SULFIDE 1%	CAVTECH HOLDING LLC	56022f6b-d7ba-1ccd-e063-6294a90a7310	2026-07-07	Warnings	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1043244	head & shoulders 1 % Medicated Shampoo	PSN	c036c9a6-6507-4037-b97b-1b015dd950c1	13
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	c036c9a6-6507-4037-b97b-1b015dd950c1	13
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	c036c9a6-6507-4037-b97b-1b015dd950c1	13
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	c036c9a6-6507-4037-b97b-1b015dd950c1	13
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	c036c9a6-6507-4037-b97b-1b015dd950c1	13
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	c036c9a6-6507-4037-b97b-1b015dd950c1	13
209884	zinc pyrithione 1 % Medicated Conditioner	SY	c036c9a6-6507-4037-b97b-1b015dd950c1	13
209884	zinc pyrithione 1 % Medicated Shampoo	SY	c036c9a6-6507-4037-b97b-1b015dd950c1	13

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
37000-078-83	37000007883	835 mL in 1 BOTTLE, PUMP (37000-078-83)	835 ml	2022-12-01	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Head and Shoulders ® Green Apple 2in1	The Procter & Gamble Manufacturing Company	2026-03-12	HUMAN OTC DRUG LABEL	14