Crest Complete Multi-Benefit

Product NDC: 37000-822
11-digit product format: 370000822
Labeler code: 37000
Product ID: 37000-822_47e49920-ad71-b3f8-e063-6294a90ae9fc
Type: HUMAN OTC DRUG
Nonproprietary name: Sodium Fluoride
Dosage form: GEL, DENTIFRICE
Route: DENTAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M021
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2011-07-01
Substance: SODIUM FLUORIDE
Active strength: 1.1 mg/g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Crest Complete Multi-Benefit
Brand name suffix: Plus Scope
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
SODIUM FLUORIDE	1.1 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8ZYQ1474W7	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
891775	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8c91095d-88c0-4d22-a79a-7d0f0d05302b	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717

FDA-Initiated Inactive NDC Indexing#

Effective, Related label table
Effective	Related label
2023-05-19	Crest ® complete MULTI-BENEFIT™
2023-05-19	Crest ® complete MULTI-BENEFIT™
2023-05-19	Crest ® complete MULTI-BENEFIT™
2023-01-30	Crest ® complete MULTI-BENEFIT™
2023-01-30	Crest ® complete MULTI-BENEFIT™
2023-01-30	Crest ® complete MULTI-BENEFIT™
2021-02-12	Crest ® complete MULTI-BENEFIT™
2021-02-12	Crest ® complete MULTI-BENEFIT™
2021-02-12	Crest ® complete MULTI-BENEFIT™
2021-01-29	Crest ® complete MULTI-BENEFIT™
2021-01-29	Crest ® complete MULTI-BENEFIT™
2021-01-29	Crest ® complete MULTI-BENEFIT™

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
37000-822-04	Crest Complete Multi-BenefitPlus Scope	130 g in 1 BOTTLE	GEL, DENTIFRICE	130		15

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Sodium Fluoride	ACTIVE INGREDIENT	8ZYQ1474W7	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
Fluoride Ion	ACTIVE MOIETY	Q80VPU408O	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
alcohol	INACTIVE INGREDIENT	3K9958V90M	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
benzoic acid	INACTIVE INGREDIENT	8SKN0B0MIM	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
carboxymethylcellulose sodium	INACTIVE INGREDIENT	K679OBS311	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
cetylpyridinium chloride	INACTIVE INGREDIENT	D9OM4SK49P	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
fd&c blue no. 1	INACTIVE INGREDIENT	H3R47K3TBD	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
fd&c yellow no. 5	INACTIVE INGREDIENT	I753WB2F1M	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
glycerin	INACTIVE INGREDIENT	PDC6A3C0OX	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
hydrated silica	INACTIVE INGREDIENT	Y6O7T4G8P9	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
polysorbate 80	INACTIVE INGREDIENT	6OZP39ZG8H	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
saccharin sodium	INACTIVE INGREDIENT	SB8ZUX40TY	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
sodium benzoate	INACTIVE INGREDIENT	OJ245FE5EU	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
sodium phosphate	INACTIVE INGREDIENT	SE337SVY37	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
sorbitol	INACTIVE INGREDIENT	506T60A25R	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3
water	INACTIVE INGREDIENT	059QF0KO0R	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [PROCTER & GAMBLE MANUFACTURING COMPANY]	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
37000-822	CREST COMPLETE MULTI-BENEFIT PLUS SCOPE (SODIUM FLUORIDE) GEL, DENTIFRICE [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	13	Current NDC, Legacy NDC, 1 package rows	20250227_8c91095d-88c0-4d22-a79a-7d0f0d05302b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 36 of 50 · 995 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Cloveden Sensitive Care Tooth	SODIUM FLUORIDE	DONG IL PHARMS CO.,LTD	3fb153f1-ba6e-7251-e063-6294a90abe62	2025-09-26	Warnings	Exact identifier application number: M021
Cloveden 100 times higher concentrated	CETYLPYRIDINIUM CHLORIDE	DONG IL PHARMS CO.,LTD	3fb1a2ee-381e-a9e8-e063-6394a90a864b	2025-09-26	Warnings	Exact identifier application number: M021
unpa Cha Cha Toothpaste	SODIUM MONOFLUOROPHOSPHATE	Lycl Inc.	230b3cf2-053a-4e8b-8d50-05bbc877faa8	2025-09-25	Warnings	Exact identifier application number: M021
TheraBreath Anticavity	SODIUM FLUORIDE	Church & Dwight Co., Inc.	3c5d58f1-ea8c-4708-bbc6-21e1cd1446da	2025-09-19	Warnings	Exact identifier application number: M021
Optimax Professional Whitening Anticavity Fluoride	SODIUM MONOFLUOROPHOSPHATE	WHITE GLO USA INC	8c4b9db9-8f23-4dd5-ab6e-1c2f9a3da5b1	2025-09-18	Warnings	Exact identifier application number: M021
Optimax Professional Whitening Anticavity Fluoride	SODIUM MONOFLUOROPHOSPHATE	WHITE GLO USA INC	c1bbdd36-53fb-43a3-ba20-afbeb6359d31	2025-09-18	Warnings	Exact identifier application number: M021
Brush Buddies Cookies n Cream Ice Cream FLAVORED Anticavity Fluoride	SODIUM FLUORIDE	Ashtel Studios, Inc.	f70d378b-d4d6-454c-90a9-794459960c8c	2025-09-17	Warnings	Exact identifier application number: M021
Brush Buddies Chocolate Ice Cream FLAVORED Anticavity Fluoride	SODIUM FLUORIDE	Ashtel Studios, Inc.	26b9b2dd-7cb2-47c3-8bbb-94a48f02dd21	2025-09-16	Warnings	Exact identifier application number: M021
Brush Buddies Mint Chocolate Chip Ice Cream FLAVORED Anticavity Fluoride	SODIUM FLUORIDE	Ashtel Studios, Inc.	3436532d-e078-4dbb-a823-b4542e961534	2025-09-16	Warnings	Exact identifier application number: M021
Colgate Total Plaque Pro Release Fresh Mint	STANNOUS FLUORIDE	Colgate-Palmolive Company	9b1671c4-8680-6e2a-9f10-0400840ca5a9	2025-09-12	Warnings	Exact identifier application number: M021
Colgate Total Plaque Pro Release Whitening	STANNOUS FLUORIDE	Colgate-Palmolive Company	ddc09ce5-181a-1b50-7094-314bb58a15cf	2025-09-12	Warnings	Exact identifier application number: M021
Cavity Protection Fresh Mint Anticavity Mouthwash	SODIUM FLUORIDE	Oxyfresh Worldwide Inc	3efc66b2-fcf9-4d26-9cdd-1af8225312b4	2025-09-10	Warnings	Exact identifier application number: M021
CLOSE UP Freshening with Mouthwash	SODIUM FLUORIDE	Church & Dwight Co., Inc.	e660b0d7-4cc5-4028-bdf5-016b85899728	2025-09-09	Warnings	Exact identifier application number: M021
Essentials Healthy Teeth and Gums	SODIUM FLUORIDE 0.24%	Church & Dwight Co., Inc.	9652c004-6b47-840f-e053-2995a90a6e98	2025-09-09	Warnings	Exact identifier application number: M021
Complete Care Whole Mouth Protection	SODIUM FLUORIDE	Church & Dwight Co., Inc.	d00f9d16-de0e-4ffc-e053-2a95a90a2069	2025-09-09	Warnings	Exact identifier application number: M021
Brush Buddies Vanilla Ice Cream FLAVORED Anticavity Fluoride	SODIUM FLUORIDE	Ashtel Studios, Inc.	e911effb-d59f-4054-9501-803b64369ab4	2025-09-05	Warnings	Exact identifier application number: M021
The Simpsons Purple Squishee Flavor Sodium Fluoride Anticavity Toothpast	SODIUM FLUORIDE	HISMILE PTY LTD	3de10638-1a39-b747-e063-6294a90a4ca5	2025-09-03	Warnings	Exact identifier application number: M021
Optimax Purple Anticavity Fluoride	SODIUM MONOFLUOROPHOSPHATE	WHITE GLO USA INC	8264e849-a6b3-4953-a85b-da9d4e7f5a70	2025-09-02	Warnings	Exact identifier application number: M021
CAREKON ANTI-CAVITY FLUORIDE	SODIUM MONOFLUOROPHOSPHATE	Hunan Yinhuatang Pharmaceutical Technology Co., Ltd.	3baca3b6-ff48-0579-e063-6394a90abd08	2025-08-29	Warnings	Exact identifier application number: M021
Brush Buddies 2 VALUE PACK CAVITY PROTECTION ANTI-CAVITY FLUORIDE	SODIUM MONOFLUOROPHOSPHATE	Ashtel Studios, Inc.	fc794fe5-7135-4b2b-b002-a75908223f20	2025-08-13	Warnings	Exact identifier application number: M021

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
8ZYQ1474W7	SODIUM FLUORIDE	7681-49-4	SODIUM FLUORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
891775	sodium fluoride 0.243 % Toothpaste	PSN	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15
891775	sodium fluoride 0.00243 MG/MG Toothpaste	SCD	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15
891775	sodium fluoride 0.243 % (fluoride ion 0.13 % ) Toothpaste	SY	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15
891775	sodium fluoride 0.243 % (fluoride ion 0.14 % ) Toothpaste	SY	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15
891775	sodium fluoride 0.243 % (fluoride ion 0.15 % ) Toothpaste	SY	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15
891775	sodium fluoride 0.243 % (fluoride ion 0.16 % ) Toothpaste	SY	8c91095d-88c0-4d22-a79a-7d0f0d05302b	15

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
37000-822-04	37000082204	130 g in 1 BOTTLE (37000-822-04)	130 g	2011-07-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Crest ® complete MULTI-BENEFIT™	The Procter & Gamble Manufacturing Company	2026-01-08	HUMAN OTC DRUG LABEL	15