Crest Premium Plus
- Product NDC
- 37000-993
- 11-digit product format
- 370000993
- Labeler code
- 37000
- Product ID
- 37000-993_47e343c9-2e62-c288-e063-6394a90a0b5c
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Sodium Fluoride
- Dosage form
- PASTE, DENTIFRICE
- Route
- DENTAL
- Labeler
- The Procter & Gamble Manufacturing Company
- Application
- M021
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2021-01-01
- Substance
- SODIUM FLUORIDE
- Active strength
- 1.5 mg/g
- NDC exclude flag
- No
- Listing certified through
- 2027-12-31
- Current FDA listing
- Yes
NDC auxiliary status#
These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.
| Dataset | Scope | Product NDC | Package NDC | Code | Status | Reporting period | Source date |
|---|---|---|---|---|---|---|---|
| excluded package | package | 37000-993 | 37000-993-35 | D | Discontinued by firm | 2026-10-12 |
Observed NDC auxiliary status history#
This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
| Captured / source date | Package NDC | Snapshot | Source SHA-256 |
|---|---|---|---|
| 2025-12-14 17:58 UTC · source 2025-12-05 | 37000-993-35 | d630ba8d3edf… | 732f749b63fb… |
| 2025-08-27 00:01 UTC · source 2025-08-26 | 37000-993-35 | f5e01cc5f278… | a2eaf40c39c3… |
| 2025-04-01 02:39 UTC · source 2025-03-31 | 37000-993-52 | 2ef7874e63bc… | 57b86245f4fa… |
| 2025-03-28 20:22 UTC · source 2025-03-28 | 37000-993-52 | a1b67e2a42f9… | c4cf2c586c0d… |
| 2025-03-22 03:12 UTC · source 2025-03-21 | 37000-993-52 | cfe11265f3b6… | 090c488252e2… |
| 2025-03-10 12:48 UTC · source 2025-03-10 | 37000-993-52 | cdf11ea48f46… | ba0047e9e063… |
| 2025-02-02 03:52 UTC · source 2025-01-31 | 37000-993-52 | 302b2466d912… | e7b80fea0513… |
| 2025-01-20 13:05 UTC · source 2025-01-20 | 37000-993-52 | ed331223b511… | 672a5bd82f5f… |
| 2025-01-11 03:41 UTC · source 2025-01-10 | 37000-993-52 | 0efc9e666f02… | f202fb6c5f17… |
| 2024-11-09 02:27 UTC · source 2024-11-08 | 37000-993-52 | ad56d346431e… | cc804d4bbf1e… |
| 2024-10-04 04:10 UTC · source 2024-10-03 | 37000-993-52 | 367a005e9d99… | 383a685ebd0f… |
| 2024-07-10 04:00 UTC · source 2024-07-09 | 37000-993-52 | 557ba5c1ecfa… | 9c80585c8c6e… |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- Crest Premium Plus
- Brand name suffix
- Advanced Whitening Active Foam
- Listing expiration
- 2027-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| SODIUM FLUORIDE | 1.5 mg/g |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| 8ZYQ1474W7 | Internal UNII lookup |
Harmonized RxCUI identifiers#
| Identifier | FDA.report destination |
|---|---|
| 891775 | Internal RxNorm lookup |
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| b81a22dc-b759-24cd-e053-2995a90a9148 | Available on FDA.report |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Related label |
|---|---|---|
| 37000-993-52 | 2023-03-31 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-52 | 2023-03-31 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-72 | 2023-03-31 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-72 | 2023-03-31 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-52 | 2023-01-30 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-52 | 2023-01-30 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-72 | 2023-01-30 | Crest Premium Plus Advanced Whitening Active Foam |
| 37000-993-72 | 2023-01-30 | Crest Premium Plus Advanced Whitening Active Foam |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 37000-993-35 | Crest Premium PlusAdvanced Whitening Active Foam | 3 in 1 CARTON | PASTE, DENTIFRICE | 3 | 12 | |
| 37000-993-35 | Crest Premium PlusAdvanced Whitening Active Foam | 147 g in 1 TUBE | PASTE, DENTIFRICE | 147 | 12 | |
| 37000-993-52 | Crest Premium PlusAdvanced Whitening Active Foam | 147 g in 1 TUBE | PASTE, DENTIFRICE | 147 | 12 | |
| 37000-993-52 | Crest Premium PlusAdvanced Whitening Active Foam | 1 in 1 CARTON | PASTE, DENTIFRICE | 1 | 12 | |
| 37000-993-72 | Crest Premium PlusAdvanced Whitening Active Foam | 1 in 1 CARTON | PASTE, DENTIFRICE | 1 | 12 | |
| 37000-993-72 | Crest Premium PlusAdvanced Whitening Active Foam | 204 g in 1 TUBE | PASTE, DENTIFRICE | 204 | 12 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 37000-993 | CREST PREMIUM PLUS ADVANCED WHITENING ACTIVE FOAM (SODIUM FLUORIDE) PASTE, DENTIFRICE [THE PROCTER & GAMBLE MANUFACTURING COMPANY] | 10 | Current NDC, Legacy NDC, 6 package rows | 20250115_b81a22dc-b759-24cd-e053-2995a90a9148.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Colgate Total SF Whitening | STANNOUS FLUORIDE | Colgate-Palmolive Company | 3bba340e-2a62-3b04-41b5-0ed9c13adb13 | 2026-04-22 | Warnings | M021 |
| EverSmile Squirt | SODIUM FLUORIDE 0.05% | Everbrands, Inc. | bc0ef174-2909-469a-b629-0eab4412bdfc | 2026-04-20 | Warnings | M021 |
| Gum Detoxify | STANNOUS FLUORIDE | Walmart | 41d6cc7a-0b87-e474-e063-6294a90ae995 | 2026-04-20 | Warnings | M021 |
| Eversmile Squirt | 2.65% HYDROGEN PEROXIDE | Everbrands, Inc. | 2c43dedf-eeb0-43ba-a352-3d56ffd9d6cf | 2026-04-19 | Warnings | M021 |
| Alcohol-Free Anticavity | SODIUM FLUORIDE | H E B | 8d40f693-083c-4eb6-9da1-42675d757e0e | 2026-04-16 | Warnings, Adverse reactions | M021 |
| Eversmile OrthoFoam Anticavity | 0.05% SODIUM FLUORIDE RINSE | Everbrands, Inc. | 9c12e792-94c8-4e29-9a54-e7e70aadade6 | 2026-04-16 | Warnings | M021 |
| Eversmile Squirt | 2.65% HYDROGEN PEROXIDE | Everbrands, Inc. | 6753b426-6d49-4438-a52f-c28e60a0e9d8 | 2026-04-16 | Warnings | M021 |
| Osstem G Gum Health Care Tooth | SODIUM FLUORIDE | Osstem Pharma Co., Ltd | 4f8b4fc0-4c98-5e52-e063-6394a90af710 | 2026-04-15 | Warnings | M021 |
| Crest 3D White Deep Stain Remover Enamel Strength | SODIUM MONOFLUOROPHOSPHATE | The Procter & Gamble Manufacturing Company | 4f6b8851-c778-8abd-e063-6294a90aef4f | 2026-04-14 | M021 | |
| Crest 3D White Stain Eraser Luxe Mint | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 4f6beb3b-2521-bfb7-e063-6394a90ad9ea | 2026-04-14 | M021 | |
| Kids Crest Strawberry Rush | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 6d96c5bb-d8d9-fbf6-e053-2a91aa0a5d13 | 2026-04-14 | Warnings | M021 |
| Crest Pro-Health Mouthwash Multi-Protection Strong Mint | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 4f6d11b2-5aa2-ab34-e063-6294a90ac0bc | 2026-04-14 | Warnings | M021 |
| Anticavity Fluoride Rinse | SODIUM FLUORIDE | Publix Super Markets, Inc. | cb6850e9-ba3e-47ac-a3ca-5de4d57c01cb | 2026-04-14 | Warnings, Adverse reactions | M021 |
| Anticavity | SODIUM FLUORIDE | Publix Super Markets, Inc. | f0e84078-499f-4a5a-bcd2-23f57805de86 | 2026-04-14 | Warnings, Adverse reactions | M021 |
| Crest Pro-Health Advanced Multi-Protection | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 1cfc5b61-c8e5-943d-e063-6394a90a890b | 2026-04-14 | Warnings | M021 |
| Crest Pro-Health Multi-Protection plus Extra Whitening | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 4f6f6299-f95f-2f0e-e063-6294a90a1641 | 2026-04-14 | Warnings | M021 |
| Crest 3D White Strength Whitening Enamel Protection | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 4f7125aa-3aa2-ca64-e063-6394a90a4cf3 | 2026-04-14 | Warnings | M021 |
| Eversmile TheraFoam | 0.05% SODIUM FLUORIDE RINSE | Everbrands, Inc. | 57da2479-923a-45ec-8149-57b469b11637 | 2026-04-13 | Warnings | M021 |
| Crest Pro-Health Advanced Bacteria Protection | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 4f1ce508-fe6e-4045-e063-6294a90ab3e2 | 2026-04-10 | Warnings | M021 |
| Crest Pro-Health Sensitivity Relief | SODIUM FLUORIDE AND POTASSIUM NITRATE | The Procter & Gamble Manufacturing Company | 4f1d62ae-653e-3046-e063-6294a90abbf8 | 2026-04-10 | Warnings | M021 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 891775 | sodium fluoride 0.243 % Toothpaste | PSN | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
| 891775 | sodium fluoride 0.00243 MG/MG Toothpaste | SCD | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
| 891775 | sodium fluoride 0.243 % (fluoride ion 0.13 % ) Toothpaste | SY | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
| 891775 | sodium fluoride 0.243 % (fluoride ion 0.14 % ) Toothpaste | SY | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
| 891775 | sodium fluoride 0.243 % (fluoride ion 0.15 % ) Toothpaste | SY | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
| 891775 | sodium fluoride 0.243 % (fluoride ion 0.16 % ) Toothpaste | SY | b81a22dc-b759-24cd-e053-2995a90a9148 | 12 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Marketing end | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|---|
| 37000-993-35 | 37000099335 | 3 in 1 CARTON | Historical | |||||
| 37000-993-52 | 37000099352 | 1 TUBE in 1 CARTON (37000-993-52) / 147 g in 1 TUBE | 1 tube | 2021-01-01 | 0000-00-00 | No | No | Current |
| 37000-993-72 | 37000099372 | 1 TUBE in 1 CARTON (37000-993-72) / 204 g in 1 TUBE | 1 tube | 2021-01-01 | 0000-00-00 | No | No | Current |