Diphenhydramine HCl and Zinc Acetate

Product NDC: 41250-058
11-digit product format: 412500058
Labeler code: 41250
Product ID: 41250-058_2479e274-3585-44d6-e063-6394a90a7810
Type: HUMAN OTC DRUG
Nonproprietary name: Extra Strength Itch Relief
Dosage form: SPRAY
Route: TOPICAL
Labeler: Meijer Distribution Inc
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2015-09-15
Marketing end: 2027-05-31
Substance: DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
Active strength: 1.52; .076 g/76g; g/76g
Pharmacologic classes: Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Diphenhydramine HCl and Zinc Acetate

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	1.52 g/76g
ZINC ACETATE	.076 g/76g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup
FM5526K07A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1053138	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
18998e1c-1254-4d0c-93f1-26652c5ca076	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
77dc03a4-fbfc-e6a3-fe95-285bbae40d75	Product name	2	20250814
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
41250-058-30	Diphenhydramine HCl and Zinc Acetate	76 g in 1 CAN	SPRAY	76		11

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
ZINC ACETATE	ACTIVE INGREDIENT	FM5526K07A	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
ZINC CATION	ACTIVE MOIETY	13S1S8SF37	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
ALCOHOL	INACTIVE INGREDIENT	3K9958V90M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
ALOE VERA LEAF	INACTIVE INGREDIENT	ZY81Z83H0X	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
TROMETHAMINE	INACTIVE INGREDIENT	023C2WHX2V	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
41250-058	DIPHENHYDRAMINE HCL AND ZINC ACETATE (EXTRA STRENGTH ITCH RELIEF) SPRAY [MEIJER DISTRIBUTION INC]	11	Current NDC, Legacy NDC, 1 package rows	20241016_18998e1c-1254-4d0c-93f1-26652c5ca076.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 54 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Welly First Aid Kit Refill	HYDROCORTISONE, BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE, LIDOCAINE	Dongguan Shenglian Tins Products Co., Ltd.	4bc93855-4009-4b49-9fb4-e5864054153d	2025-12-16	Warnings	Exact identifier application number: M017
LidocainePain pain reliving gel-patch	PAIN RELIVING GEL-PATCH	Shenzhen Yuetai Electronic Commerce Co., Ltd	461ebbdd-0f26-a333-e063-6394a90a7a3e	2025-12-16	Warnings	Exact identifier application number: M017
Zestama	CAPSAICIN	V2 Pharma LLC	c9b46759-b8df-4ff4-815e-8e032c2635c0	2025-12-15	Warnings	Exact identifier application number: M017
equate hydrocortisone	HYDROCORTISONE	Wal-Mart Stores Inc	70f4636d-4137-498b-ab81-0330de883e53	2025-12-15	Warnings	Exact identifier application number: M017
SALONPAS-HOT CAPSICUM	CAPSAICIN	Hisamitsu Pharmaceutical Co., Inc.	ef5373aa-9857-4d01-95af-2d7716e54ae4	2025-12-15	Warnings	Exact identifier application number: M017
First Aid Burn Cream	FIRST AID BURN CREAM	ProStat First Aid LLC	f70a442e-7ba7-4860-e053-6394a90ac2bd	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease, 3.5g	BURN EASE, 3.5G	ProStat First Aid LLC	004aa18f-3a97-f454-e063-6394a90afcff	2025-12-15	Warnings	Exact identifier application number: M017
PS-3866 Burn Ease, 0.9g	PS-3866 BURN EASE, 0.9G	ProStat First Aid LLC	004d00a5-9cff-29ff-e063-6294a90aeb8c	2025-12-15	Warnings	Exact identifier application number: M017
First Aid Burn Cream	FIRST AID BURN CREAM	ProStat First Aid LLC	0037a1a4-d747-2567-e063-6394a90a721c	2025-12-15	Warnings	Exact identifier application number: M017
PS-3885 Burn Ease, 3.5g	PS-3885 BURN EASE, 3.5G	ProStat First Aid LLC	004c6deb-2844-a0d0-e063-6394a90ae5e4	2025-12-15	Warnings	Exact identifier application number: M017
2677 First Aid Burn Cream	2677 FIRST AID BURN CREAM	ProStat First Aid LLC	ff5bb628-8ef7-4540-e053-6394a90a55ed	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease	BURN EASE	ProStat First Aid LLC	f71b98b4-22d0-0124-e053-6394a90ae4cf	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease	BURN EASE	ProStat First Aid LLC	f71eb4f5-2280-5867-e053-6394a90aac57	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease 3.5g	BURN EASE 3.5G	Front Line Safety	0f8e6842-c889-d5d3-e063-6394a90af880	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease 3.5g	BURN EASE 3.5G	Front Line Safety	0f8c59fb-3622-2bb7-e063-6294a90adc6e	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease	BURN EASE	Front Line Safety	0e34cb09-d8c6-f8c0-e063-6294a90a0be0	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease 3.5g	BURN EASE 3.5G	Front Line Safety	0f52021f-af8a-5b95-e063-6294a90a2c2a	2025-12-15	Warnings	Exact identifier application number: M017
Burn Ease	BURN EASE	ProStat First Aid LLC	0e25c936-e40a-e23c-e063-6294a90ac0e4	2025-12-15	Warnings	Exact identifier application number: M017
Sting Relief Wipes	STING RELIEF WIPES	ProStat First Aid LLC	0e20252a-5ecb-2526-e063-6294a90a8cde	2025-12-15	Warnings	Exact identifier application number: M017
First Aid Burn Cream	FIRST AID BURN CREAM	Front Line Safety	0f4ce2c2-f306-d95f-e063-6394a90ae7b3	2025-12-15	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE
FM5526K07A	ZINC ACETATE	5970-45-6	ZINC ACETATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1053138	diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Spray	PSN	18998e1c-1254-4d0c-93f1-26652c5ca076	11
1053138	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray	SCD	18998e1c-1254-4d0c-93f1-26652c5ca076	11
1053138	diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Spray	SY	18998e1c-1254-4d0c-93f1-26652c5ca076	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
41250-058-30	41250005830	76 g in 1 CAN (41250-058-30)	76 g	2015-09-15	2027-05-31	No	No	Current