Home NDC 41250-334-08 Headache Relief
Product NDC 41250-334
Requested package NDC 41250-334-08
11-digit product format 412500334
Labeler code 41250
Product ID 41250-334_746072ad-79e2-4d14-939d-d3c4396b47f2
Type HUMAN OTC DRUG
Nonproprietary name Acetaminophen, Aspirin, Caffeine
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Meijer Distribution Inc
Application M013
Marketing category OTC MONOGRAPH DRUG
Marketing start 2008-03-13
Substance ACETAMINOPHEN; ASPIRIN; CAFFEINE
Active strength 250; 250; 65 mg/1; mg/1; mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Methylxanthine [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Xanthines [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 12 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Snapshot, Source SHA-256 table Captured / source date Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 0efc9e666f02…f202fb6c5f17…2024-11-09 02:27 UTC · source 2024-11-08 ad56d346431e…cc804d4bbf1e…2024-10-04 04:10 UTC · source 2024-10-03 367a005e9d99…383a685ebd0f…2024-07-10 04:00 UTC · source 2024-07-09 557ba5c1ecfa…9c80585c8c6e…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Headache Relief
Brand name suffix Extra Strength
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength ACETAMINOPHEN 250 mg/1 ASPIRIN 250 mg/1 CAFFEINE 65 mg/1
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 41250-334-08 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-08 Headache ReliefExtra Strength 24 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 24 18 41250-334-12 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 18 41250-334-12 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-15 Headache ReliefExtra Strength 50 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 50 18 41250-334-15 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 18 41250-334-98 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 18 41250-334-98 Headache ReliefExtra Strength 2 in 1 CARTON TABLET, FILM COATED 2 18
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded ACETAMINOPHEN ACTIVE INGREDIENT 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ASPIRIN ACTIVE INGREDIENT R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CAFFEINE ACTIVE INGREDIENT 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ACETAMINOPHEN ACTIVE MOIETY 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 ASPIRIN ACTIVE MOIETY R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CAFFEINE ACTIVE MOIETY 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 CROSPOVIDONE INACTIVE INGREDIENT 68401960MK HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 HYPROMELLOSES INACTIVE INGREDIENT 3NXW29V3WO HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 POVIDONES INACTIVE INGREDIENT FZ989GH94E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 SODIUM LAURYL SULFATE INACTIVE INGREDIENT 368GB5141J HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 STEARIC ACID INACTIVE INGREDIENT 4ELV7Z65AP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN-NSAID, CAFFEINE) TABLET, FILM COATED [MEIJER] 2
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 41250-334 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN, CAFFEINE) TABLET, FILM COATED [MEIJER DISTRIBUTION INC] 17 Current NDC, Legacy NDC, 8 package rows 20241211_04f2c3ed-4bcf-4b6a-b8fb-0aa6ecb3dca2.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 52 of 79 · 1,561 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join acetaminophen ACETAMINOPHEN UNFI e689c9e3-dd4d-c646-e053-2a95a90a4b6a 2024-12-09 Warnings Exact identifier application number: M013 DrKids Childrens Pain and Fever ACETAMINOPHEN 80MG/PIECE CalmCo LLC ff4b0528-39a0-80d5-e053-6394a90a8a83 2024-12-07 Warnings Exact identifier application number: M013 Pain Relief ACETAMINOPHEN DISCOUNT DRUG MART 972f09a7-2aa1-4b1b-a6dc-2c4578a07803 2024-12-05 Warnings Exact identifier application number: M013 Pain Relief Extra Strength ACETAMINOPHEN DISCOUNT DRUG MART e6feff0a-3347-194d-e053-2a95a90acd20 2024-12-05 Warnings Exact identifier application number: M013 Pain Relief Extra Strength ACETAMINOPHEN DISCOUNT DRUG MART e6fee238-0b6f-cb84-e053-2995a90a361b 2024-12-05 Warnings Exact identifier application number: M013 Menstrual Complete Maximum Strength ACETAMINOPHEN, CAFFEINE AND PYRILAMINE MALEATE L.N.K. International, Inc. 379ef03c-3b6a-40c3-b736-99f0537d26c8 2024-12-05 Warnings Exact identifier application number: M013 Pain Reliever Extra Strength ACETAMINOPHEN Marc Glassman, Inc. 43bf297f-2832-424f-a013-4bfa1d6c03e6 2024-12-04 Warnings Exact identifier application number: M013 Acetaminophen ACETAMINOPHEN Precision Dose, Inc. 5a68ab98-720c-479a-a60a-4e594add6c09 2024-12-04 Warnings Exact identifier application number: M013 HEB Effervescent Pain Relief ASPIRIN H. E. BUTT GROCERY COMPANY 03876c71-60ec-3280-e063-6294a90a62dc 2024-12-03 Warnings Exact identifier application number: M013 Migrafein FORTE ACETAMINOPHEN, CAFFEINE OPMX LLC 028875c9-4129-ce2c-e063-6294a90a26cc 2024-12-03 Warnings Exact identifier application number: M013 Neo-Lubrina Fuerte ACETAMINOPHEN, CAFFEINE OPMX LLC 0288a327-fd4b-1991-e063-6294a90ace50 2024-12-03 Warnings Exact identifier application number: M013 CAFIZETAMOL FORTE ACETAMINOPHEN, CAFFEINE OPMX LLC 028771d3-a514-f7a5-e063-6394a90ac4f3 2024-12-03 Warnings Exact identifier application number: M013 Buscapina ACETAMINOPHEN, CAFFEINE, PYRILAMINE MALEATE OPMX LLC 048c4b03-1cf4-b724-e063-6294a90a1cad 2024-12-03 Warnings Exact identifier application number: M013 Pain Relief Extra Strength ACETAMINOPHEN TopCo Associates LLC ecd6df7e-e7e2-446b-85ef-25971281fe31 2024-12-03 Warnings Exact identifier application number: M013 Market Basket Effervescent Pain Relief ASPIRIN DEMOULAS SUPER MARKETS, INC. 08133bf0-3c8f-e4d0-e063-6294a90af79a 2024-12-03 Warnings Exact identifier application number: M013 Aspirin Low Dose ASPIRIN WinCo Foods, LLC 4359da13-e851-440b-91b9-6b544bff20d2 2024-12-03 Warnings Exact identifier application number: M013 Low Dose Aspirin ASPIRIN WinCo Foods, LLC 5b3e8a78-5357-42ad-811e-b2578b25dc7b 2024-12-03 Warnings Exact identifier application number: M013 Low Strength Chewable Aspirin ASPIRIN Geri-Care Pharmaceutical Corp cc77b9d1-7874-4ce8-a763-3a0e1c2891de 2024-12-03 Warnings Exact identifier application number: M013 Good Sense Childrens Pain and Fever ACETAMINOPHEN L. Perrigo Company c6b79501-d08b-4430-9545-70da5f545975 2024-12-03 Warnings Exact identifier application number: M013 Aspirin ASPIRIN Chain Drug Marketing Association 0e3be5f4-bc1b-4b44-a86a-ace89f6ee592 2024-12-02 Warnings Exact identifier application number: M013
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 41250-334-08 41250033408 1 BOTTLE, PLASTIC in 1 CARTON (41250-334-08) > 24 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2008-03-13 0000-00-00 No No Current