Corphedra

Product NDC: 42023-233
11-digit product format: 420230233
Labeler code: 42023
Product ID: 42023-233_aa6213f5-e549-4e42-a795-b791de8353b7
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: ephedrine sulfate
Dosage form: INJECTION, SOLUTION
Route: INTRAVENOUS
Labeler: Par Pharmaceutical, Inc.
Application: NDA208943
Marketing category: NDA
Marketing start: 2019-01-18
Marketing end: 0000-00-00
Substance: EPHEDRINE SULFATE
Active strength: 500 mg/10mL
Pharmacologic classes: Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Increased Norepinephrine Activity [PE], Norepinephrine Releasing Agent [EPC], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag: No
Listing certified through: 2023-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded product	product	42023-233		D	Discontinued by firm		2026-08-10
excluded package	package	42023-233	42023-233-01	D	Discontinued by firm		2026-08-10

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 20 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	42023-233-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	42023-233-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	42023-233-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	42023-233-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	42023-233-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	42023-233-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	42023-233-01	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	42023-233-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	42023-233-01	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	42023-233-01	`ad56d346431e…`	`cc804d4bbf1e…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N208943-001	CORPHEDRA	EPHEDRINE SULFATE	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP		2017-01-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-product	TE code
N208943-001	AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N208943-001	CORPHEDRA	50MG/ML (50MG/ML)	SOLUTION / INTRAVENOUS	AP	2017-01-27	`cb3db0bc1861…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N208943-001	AP	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N208943-001	AP	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N208943-001	AP	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N208943-001	AP	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N208943-001	AP	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N208943-001	AP	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N208943-001	AP	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N208943-001	AP	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N208943-001	AP	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N208943-001	AP	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N208943-001	AP	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N208943-001	AP	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N208943-001	AP	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N208943-001	AP	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N208943-001	AP	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N208943-001	AP	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N208943-001	AP	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N208943-001	AP	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N208943-001	AP	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N208943-001	AP	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N208943-001	AP	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N208943-001	AP	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N208943-001	AP	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N208943-001	AP	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N208943-001	AP	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N208943-001	AP	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N208943-001	AP	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N208943-001	AP	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N208943-001	AP	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N208943-001	AP	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N208943-001	AP	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N208943-001	AP	1	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N208943-001	AP	1	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N208943-001	AP	1	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N208943-001	AP	1	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N208943-001	AP	1	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N208943-001	AP	1	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N208943-001	AP	1	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N208943-001	AP	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N208943-001	AP	1	`cb3db0bc1861…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Ephedrine Sulfate	EPHEDRINE SULFATE	Par Health USA, LLC	38723cb3-dfca-4c81-8c6f-63dd99929191	2026-03-17	Warnings, Adverse reactions	Exact identifier application applno (NDA): 208943 application number: NDA208943
Ephedrine Sulfate	EPHEDRINE SULFATE	Par Health USA, LLC	3e43cc8e-bf4e-44ef-a07d-4336367b9bdb	2026-01-21	Warnings, Adverse reactions	Exact identifier application applno (NDA): 208943 application number: NDA208943
EPHEDRINE SULFATE	EPHEDRINE SULFATE	HF Acquisition Co LLC, DBA HealthFirst	78c1daef-6e1e-5f2c-e053-2a91aa0a0dba	2024-02-26	Warnings, Adverse reactions	Exact identifier application applno (NDA): 208943 application number: NDA208943

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
U6X61U5ZEG	EPHEDRINE SULFATE	134-72-5	EPHEDRINE SULFATE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
42023-233-01	42023023301	10 mL in 1 VIAL (42023-233-01)	10 ml	2019-01-18	0000-00-00	No	No	Current