Allergy Relief

Product NDC: 42507-290
11-digit product format: 425070290
Labeler code: 42507
Product ID: 42507-290_48494a07-2a50-2d2a-e063-6294a90a6570
Type: HUMAN OTC DRUG
Nonproprietary name: DIPHENHYDRAMINE HYDROCHLORIDE
Dosage form: TABLET, COATED
Route: ORAL
Labeler: HYVEE INC
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2025-10-22
Substance: DIPHENHYDRAMINE HYDROCHLORIDE
Active strength: 25 mg/1
Pharmacologic classes: Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Allergy Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1049630	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3e608643-1a74-b474-e063-6294a90ad2e0	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
42507-290-01	Allergy Relief	12 in 1 BLISTER PACK	TABLET, COATED	12	3
42507-290-01	Allergy Relief	2 in 1 CARTON	TABLET, COATED	2	3
42507-290-03	Allergy Relief	1 in 1 CARTON	TABLET, COATED	1	3
42507-290-03	Allergy Relief	100 in 1 BOTTLE, PLASTIC	TABLET, COATED	100	3
42507-290-05	Allergy Relief	400 in 1 BOTTLE, PLASTIC	TABLET, COATED	400	3

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 59 of 180 · 3,583 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Vapo Steam	VAPO STEAM	TOPCO ASSOCIATES, LLC	f216f69f-9580-25ac-e053-2995a90a5ac6	2026-01-14	Warnings	Exact identifier application number: M012
Leader Vapor Ice Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE	Cardinal Health 110, LLC. dba Leader	f27bf0b2-25cc-474c-ab6b-f227ed3525fa	2026-01-14	Warnings	Exact identifier application number: M012
Sinus PE plus Allergy	CHLORPHENIRAMINE MALEATE AND PHENYLEPHRINE HCL	Walgreen Company	a15979d4-87bf-42e7-b1f2-783496072141	2026-01-13	Warnings	Exact identifier application number: M012
Nighttime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE	BETTER LIVING BRANDS LLC.	41f4bf6d-f83c-92e4-e063-6394a90aebab	2026-01-13	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HYDROCHLORIDE	HYVEE INC	3e608643-1a74-b474-e063-6294a90ad2e0	2026-01-13	Warnings	Exact identifier application number: M012 ndc (product): 42507-290
Severe Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE	HYVEE INC	462cbf3d-51b1-dab9-e063-6394a90a70ba	2026-01-13	Warnings	Exact identifier application number: M012
Pocket Farmacy	MENTHOL	Saje Natural Business Inc.	4260542e-0980-4b0b-8177-1c9f2c53b5a6	2026-01-13	Warnings	Exact identifier application number: M012
Sweet Comfort	MENTHOL	Saje Natural Business Inc.	cf13cccd-723d-4d61-8a5e-b36281605cc7	2026-01-13	Warnings	Exact identifier application number: M012
Fortify	MENTHOL	Saje Natural Business Inc.	0320a305-99d1-4909-94cc-cd6509ecb948	2026-01-13	Warnings	Exact identifier application number: M012
Rolling Farmacy	MENTHOL	Saje Natural Business Inc.	a38765a9-22cd-4fc5-b5ab-c3cacbd52c74	2026-01-13	Warnings	Exact identifier application number: M012
Home Farmacy	MENTHOL	Saje Natural Business Inc.	add35d10-b27a-4ae8-b2de-8a285aaef155	2026-01-13	Warnings	Exact identifier application number: M012
Traveling Farmacy	MENTHOL	Saje Natural Business Inc.	5b70f5aa-ed36-65ab-e053-2a91aa0a6777	2026-01-13	Warnings	Exact identifier application number: M012
sinus plus allergy PE maximum strength	CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HCL	United Natural Foods, Inc. dba UNFI	660d3c80-f249-41dd-aa93-a0b1e635ead0	2026-01-13	Warnings	Exact identifier application number: M012
Chest Comfort	MENTHOL	Saje Natural Business Inc.	8a3db169-6dd7-4dfd-8360-90315288f21b	2026-01-12	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HCL	H E B	c9e977b6-fba6-49ea-9d80-b43b0842bbe1	2026-01-12	Warnings	Exact identifier application number: M012
PE Sinus Congestion	PHENYLEPHRINE HCL	Topco Associates, LLC	3264e291-7a0f-4e25-8390-ba441f22f650	2026-01-12	Warnings	Exact identifier application number: M012
Childrens Allergy Relief	DIPHENHYDRAMINE HCL	CVS PHARMACY	3f44cff6-240a-4a8d-aaa1-0da75a31a47b	2026-01-12	Warnings	Exact identifier application number: M012
Suphedrine PE Sinus Congestion Non-Drowsy	PHENYLEPHRINE HCL	ARMY AND AIR FORCE EXCHANGE SERVICE	b9122fd0-0bed-4302-9bbe-cd6a46d29818	2026-01-12	Warnings	Exact identifier application number: M012
Sinu-Phen Plus Sinus Pain and Pressure	ACETAMINOPHEN, PHENYLEPHRINE HYDROCHLORIDE	Wildman Business Group	c66e0b52-5531-4a84-ae90-8a26d27df1ec	2026-01-12	Warnings	Exact identifier application number: M012
SU PHEDRINE PE SINUS CONGESTION	PHENYLEPHRINE HCL	Salado Sales, Inc.	ba075ff7-4e26-4856-8335-0c7dd4e198ea	2026-01-12	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1049630	diphenhydrAMINE HCl 25 MG Oral Tablet	PSN	3e608643-1a74-b474-e063-6294a90ad2e0	3
1049630	diphenhydramine hydrochloride 25 MG Oral Tablet	SCD	3e608643-1a74-b474-e063-6294a90ad2e0	3

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
42507-290-01	42507029001	2 BLISTER PACK in 1 CARTON (42507-290-01) / 12 TABLET, COATED in 1 BLISTER PACK	2 blister pack	2025-10-22	No	No	Current
42507-290-03	42507029003	1 BOTTLE, PLASTIC in 1 CARTON (42507-290-03) / 100 TABLET, COATED in 1 BOTTLE, PLASTIC		2026-01-13	No	No	Current
42507-290-05	42507029005	400 TABLET, COATED in 1 BOTTLE, PLASTIC (42507-290-05)		2026-01-13	No	No	Current