Home NDC 42507-622 Itch Stopping
Product NDC 42507-622
11-digit product format 425070622
Labeler code 42507
Product ID 42507-622_7a9541e1-5f0c-4547-81bd-647e1344bf12
Type HUMAN OTC DRUG
Nonproprietary name Diphenhydramine Hydrochloride, Zinc Acetate
Dosage form CREAM
Route TOPICAL
Labeler HyVee Inc
Application M017
Marketing category OTC MONOGRAPH DRUG
Marketing start 2015-09-27
Substance DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
Active strength 2; .1 g/100g; g/100g
Pharmacologic classes Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 24 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Dataset, Scope table Captured / source date Dataset Scope Package NDC Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 excluded product product d630ba8d3edf…732f749b63fb…2025-12-14 17:58 UTC · source 2025-12-05 excluded package package 42507-622-64 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 excluded product product f5e01cc5f278…a2eaf40c39c3…2025-08-27 00:01 UTC · source 2025-08-26 excluded package package 42507-622-64 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 excluded product product 2ef7874e63bc…57b86245f4fa…2025-04-01 02:39 UTC · source 2025-03-31 excluded package package 42507-622-64 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 excluded product product a1b67e2a42f9…c4cf2c586c0d…2025-03-28 20:22 UTC · source 2025-03-28 excluded package package 42507-622-64 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 excluded product product cfe11265f3b6…090c488252e2…2025-03-22 03:12 UTC · source 2025-03-21 excluded package package 42507-622-64 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 excluded product product cdf11ea48f46…ba0047e9e063…2025-03-10 12:48 UTC · source 2025-03-10 excluded package package 42507-622-64 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 excluded product product 302b2466d912…e7b80fea0513…2025-02-02 03:52 UTC · source 2025-01-31 excluded package package 42507-622-64 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 excluded product product ed331223b511…672a5bd82f5f…2025-01-20 13:05 UTC · source 2025-01-20 excluded package package 42507-622-64 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 excluded product product 0efc9e666f02…f202fb6c5f17…2025-01-11 03:41 UTC · source 2025-01-10 excluded package package 42507-622-64 0efc9e666f02…f202fb6c5f17…2024-11-09 02:27 UTC · source 2024-11-08 excluded product product ad56d346431e…cc804d4bbf1e…2024-11-09 02:27 UTC · source 2024-11-08 excluded package package 42507-622-64 ad56d346431e…cc804d4bbf1e…2024-10-04 04:10 UTC · source 2024-10-03 excluded product product 367a005e9d99…383a685ebd0f…2024-10-04 04:10 UTC · source 2024-10-03 excluded package package 42507-622-64 367a005e9d99…383a685ebd0f…2024-07-10 04:00 UTC · source 2024-07-09 excluded product product 557ba5c1ecfa…9c80585c8c6e…2024-07-10 04:00 UTC · source 2024-07-09 excluded package package 42507-622-64 557ba5c1ecfa…9c80585c8c6e…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Itch Stopping
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength DIPHENHYDRAMINE HYDROCHLORIDE 2 g/100g ZINC ACETATE .1 g/100g
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination TC2D6JAD40 Internal UNII lookup FM5526K07A Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1087026 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded DIPHENHYDRAMINE HYDROCHLORIDE ACTIVE INGREDIENT TC2D6JAD40 ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 ZINC ACETATE ACTIVE INGREDIENT FM5526K07A ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 DIPHENHYDRAMINE ACTIVE MOIETY 8GTS82S83M ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 ZINC CATION ACTIVE MOIETY 13S1S8SF37 ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 CETYL ALCOHOL INACTIVE INGREDIENT 936JST6JCN ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 DIAZOLIDINYL UREA INACTIVE INGREDIENT H5RIZ3MPW4 ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 METHYLPARABEN INACTIVE INGREDIENT A2I8C7HI9T ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 PEG-2 STEARATE INACTIVE INGREDIENT 94YQ11Y95F ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 PEG-20 STEARATE INACTIVE INGREDIENT NBX892EA57 ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 PROPYLPARABEN INACTIVE INGREDIENT Z8IX2SC1OH ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1 WATER INACTIVE INGREDIENT 059QF0KO0R ITCH STOPPING (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [HYVEE INC] 1
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 130 of 151 · 3,010 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Eagle Brand Medicated Oil MENTHOL, METHYL SALICYLATE PT. EAGLE INDO PHARMA 1bc1bf83-91ee-ec9d-e063-6394a90a3daf 2024-06-25 Warnings Exact identifier application number: M017 Eagle Brand Medicated Roll On MENTHOL, METHYL SALICYLATE Borden Company (Private) Limited 1bc2f688-d0c4-690e-e063-6294a90abc38 2024-06-25 Warnings Exact identifier application number: M017 Eagle Brand Medicated Oil MENTHOL, METHYL SALICYLATE Borden Company (Private) Limited 1b9fdac0-9fb0-e669-e063-6394a90aece9 2024-06-24 Warnings Exact identifier application number: M017 Capsaicin CAPSAICIN Asclemed USA, Inc. 97d506bd-3215-4e2e-9914-af1c174dd4ab 2024-06-20 Warnings Exact identifier application number: M017 ABREVA Rapid Pain Relief GLYCERIN, LIDOCAINE Haleon US Holdings LLC 65bd242f-4c6a-436c-8ec0-7b2e0d73ed9d 2024-06-20 Warnings Exact identifier application number: M017 Frankie Avalons ZERO PAIN Roll-On Pain Reliever CAPSAICIN WHY ENTERPRISES LLC e32acb5f-5bc3-4228-b037-6315d080f556 2024-06-17 Warnings Exact identifier application number: M017 PUREGEN LABS Pain Relief 4 Lidocaine LIDOCAINE Advanced Rx LLC 9dff40d8-8d7e-4629-bea5-987f5e68477d 2024-06-11 Warnings Exact identifier application number: M017 SMOOTH GATOR Head-Ezz Analgesic MENTHOL Smooth Gator LLC 02e18e5d-6fb0-4ebf-bdd6-dcc7edbb31bd 2024-06-10 Warnings Exact identifier application number: M017 FIRST AID BURN LIDOCAINE HYDROCHLORIDE,BENZALKONIUM CHLORIDE Epic Medical Supply Corp bd1b1873-e900-45eb-96a0-28f782b5a7cd 2024-06-04 Warnings Exact identifier application number: M017 Hydrocortisone 1% HYDROCORTISONE Chain Drug Marketing Association Inc. 1c834ba0-86b6-8e61-e063-6394a90a192d 2024-06-04 Warnings Exact identifier application number: M017 HealthWise Feminine Anti-itch Cream BENZOCAINE, RESORCINOL Veridian Healthcare 19fe7c3b-58e2-6c16-e063-6394a90a612a 2024-06-03 Warnings Exact identifier application number: M017 THE SOLUTION NUMBING LIDOCAINE HYDROCHLORIDE SCALP TECH INC 184be4cc-b0b9-7882-e063-6394a90a8e7e 2024-05-25 Warnings Exact identifier application number: M017 Methyl Salicylate 25 Percent METHYL SALICYLATE Alexso, Inc d8b8b0ba-69e9-4965-bf9b-6db21db69b34 2024-05-23 Warnings Exact identifier application number: M017 Meijer Medicated Chest Rub CAMPHOR, MENTHOL, EUCALYPTUS OIL Meijer Distribution 07ecc6a7-bbe3-35cf-e063-6394a90a2180 2024-05-22 Warnings Exact identifier application number: M017 TheraCare Hydrocortisone Cream HYDROCORTISONE Veridian Healthcare 01cb7b47-2c3c-707d-e063-6294a90a5d97 2024-05-21 Warnings Exact identifier application number: M017 TheraCare 4% Lidocaine Cream LIDOCAINE HYDROCHLORIDE Veridian Healthcare c808aa05-9d49-cc9f-e053-2a95a90a50f3 2024-05-21 Warnings Exact identifier application number: M017 TheraCare 4% Lidocaine and 1% Menthol Cream MENTHOL AND LIDOCAINE Veridian Healthcare c80ba251-91a5-0858-e053-2995a90a9cff 2024-05-21 Warnings Exact identifier application number: M017 HealthWise Menthol Roll-On MENTHOL Veridian Healthcare 102d57a5-6449-f825-e063-6294a90a8844 2024-05-21 Warnings Exact identifier application number: M017 SAFLY Burn LIDOCAINE HYDROCHLORIDE Nantong Health & Beyond Hygienic Products Inc. 3aca2568-d10f-4b14-861b-6c741c106829 2024-05-17 Warnings Exact identifier application number: M017 HealthWise Menthol 4% Roll-On MENTHOL Veridian Healthcare 1894ef00-ba05-0e02-e063-6394a90ab982 2024-05-16 Warnings Exact identifier application number: M017
Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Sample Exclude flag Status 42507-622-64 42507062264 1 TUBE in 1 CARTON (42507-622-64) / 28 g in 1 TUBE (42507-622-28) 1 tube 2015-09-27 No No Current