Doxorubicin hydrochloride

Product NDC
45963-733
11-digit product format
459630733
Labeler code
45963
Product ID
45963-733_2ad7c99b-8cea-4e22-826f-9e49c90605b6
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Doxorubicin hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Actavis Pharma, Inc.
Application
ANDA203622
Marketing category
ANDA
Marketing start
2014-11-01
Substance
DOXORUBICIN HYDROCHLORIDE
Active strength
2 mg/mL
Pharmacologic classes
Anthracycline Topoisomerase Inhibitor [EPC], Anthracyclines [CS], Topoisomerase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203622-001DOXORUBICIN HYDROCHLORIDEDOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27
A203622-002DOXORUBICIN HYDROCHLORIDEDOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A203622-001AP
A203622-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-278072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-275c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-275d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-274b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-2774a2ff9319b5…
2019-12-13 00:20 UTC2019-12A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203622-001DOXORUBICIN HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2014-06-27782e0a99824c…
2021-12-28 21:50 UTC2021-12A203622-002DOXORUBICIN HYDROCHLORIDE200MG/100MLINJECTABLE / INJECTIONAP2014-06-27782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A203622-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A203622-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203622-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203622-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203622-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A203622-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203622-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203622-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203622-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203622-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203622-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203622-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203622-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203622-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203622-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203622-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203622-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203622-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203622-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A203622-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203622-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203622-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203622-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203622-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203622-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203622-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203622-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A203622-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203622-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203622-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203622-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A203622-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203622-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A203622-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203622-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A203622-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203622-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A203622-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203622-001AP1782e0a99824c…
2021-12-28 21:50 UTC2021-12A203622-002AP1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Doxorubicin hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DOXORUBICIN HYDROCHLORIDE2 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
82F2G7BL4EInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1191138Internal RxNorm lookup
1790097Internal RxNorm lookup
1790099Internal RxNorm lookup
1790100Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
33ddfdb1-b4bc-464d-a186-49c4b156279fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2ee64805-1a32-49b4-a119-9376fc9e6633Product name520250305
750deab0-bb49-36cc-d493-bfaec857a32eProduct name520190807

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
45963-733-55Doxorubicin hydrochloride5 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION516
45963-733-55Doxorubicin hydrochloride1 in 1 CARTONINJECTION, SOLUTION116
45963-733-57Doxorubicin hydrochloride10 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION1016
45963-733-57Doxorubicin hydrochloride1 in 1 CARTONINJECTION, SOLUTION116
45963-733-60Doxorubicin hydrochloride100 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION10016
45963-733-60Doxorubicin hydrochloride1 in 1 CARTONINJECTION, SOLUTION116
45963-733-68Doxorubicin hydrochloride25 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION2516
45963-733-68Doxorubicin hydrochloride1 in 1 CARTONINJECTION, SOLUTION116

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
45963-733-55ML - Milliliter45963-7332d0d5cd6-cd1c-4061-aac0-7bd7653b171a12015-02-02
45963-733-57ML - Milliliter45963-7331cbe4a44-08a0-4546-8dbe-c1b9b4f1855312015-02-02
45963-733-60ML - Milliliter45963-733c0683dcd-7f2f-41a1-8ed4-29f4412626e712015-02-02
45963-733-68ML - Milliliter45963-73393d0e90a-b770-4c9e-8673-2460a2e7edf612015-02-02

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
45963-733DOXORUBICIN HYDROCHLORIDE INJECTION, SOLUTION [ACTAVIS PHARMA, INC.]16Current NDC, Legacy NDC, 8 package rows20241109_33ddfdb1-b4bc-464d-a186-49c4b156279f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Doxorubicin hydrochlorideDOXORUBICIN HYDROCHLORIDEActavis Pharma, Inc.33ddfdb1-b4bc-464d-a186-49c4b156279f2024-07-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203622
application number: ANDA203622
ndc (product): 45963-733

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1790097DOXOrubicin HCl 10 MG in 5 mL InjectionPSN33ddfdb1-b4bc-464d-a186-49c4b156279f16
1191138DOXOrubicin HCl 2 MG/ML Injectable SolutionPSN33ddfdb1-b4bc-464d-a186-49c4b156279f16
1790099DOXOrubicin HCl 20 MG in 10 ML InjectionPSN33ddfdb1-b4bc-464d-a186-49c4b156279f16
1790100DOXOrubicin HCl 50 MG in 25 ML InjectionPSN33ddfdb1-b4bc-464d-a186-49c4b156279f16
179009910 ML doxorubicin hydrochloride 2 MG/ML InjectionSCD33ddfdb1-b4bc-464d-a186-49c4b156279f16
179010025 ML doxorubicin hydrochloride 2 MG/ML InjectionSCD33ddfdb1-b4bc-464d-a186-49c4b156279f16
17900975 ML doxorubicin hydrochloride 2 MG/ML InjectionSCD33ddfdb1-b4bc-464d-a186-49c4b156279f16
1191138doxorubicin hydrochloride 2 MG/ML Injectable SolutionSCD33ddfdb1-b4bc-464d-a186-49c4b156279f16
1790097doxorubicin hydrochloride 10 MG per 5 ML InjectionSY33ddfdb1-b4bc-464d-a186-49c4b156279f16
1790099doxorubicin hydrochloride 20 MG per 10 ML InjectionSY33ddfdb1-b4bc-464d-a186-49c4b156279f16
1790100doxorubicin hydrochloride 50 MG per 25 ML InjectionSY33ddfdb1-b4bc-464d-a186-49c4b156279f16

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
45963-733-55459630733551 VIAL, SINGLE-DOSE in 1 CARTON (45963-733-55) / 5 mL in 1 VIAL, SINGLE-DOSE2014-11-010000-00-00NoNoCurrent
45963-733-57459630733571 VIAL, SINGLE-DOSE in 1 CARTON (45963-733-57) / 10 mL in 1 VIAL, SINGLE-DOSE2014-11-010000-00-00NoNoCurrent
45963-733-60459630733601 VIAL, MULTI-DOSE in 1 CARTON (45963-733-60) / 100 mL in 1 VIAL, MULTI-DOSE2014-11-010000-00-00NoNoCurrent
45963-733-68459630733681 VIAL, SINGLE-DOSE in 1 CARTON (45963-733-68) / 25 mL in 1 VIAL, SINGLE-DOSE2014-11-010000-00-00NoNoCurrent