Diphenhydramine HCl and Zinc Acetate

Product NDC: 49035-015
11-digit product format: 490350015
Labeler code: 49035
Product ID: 49035-015_38917a94-449f-7050-e063-6394a90a0245
Type: HUMAN OTC DRUG
Nonproprietary name: Anti-Itch Continuous Spray
Dosage form: AEROSOL, SPRAY
Route: TOPICAL
Labeler: Wal-Mart Stores, Inc.
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2013-03-03
Marketing end: 2026-10-31
Substance: DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
Active strength: 1.5; .075 g/88mL; g/88mL
Pharmacologic classes: Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Diphenhydramine HCl and Zinc Acetate

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	1.5 g/88mL
ZINC ACETATE	.075 g/88mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup
FM5526K07A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1053138	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
709c3bb8-5b36-4823-941a-45ddb3e431c4	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
77dc03a4-fbfc-e6a3-fe95-285bbae40d75	Product name	2	20250814
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
49035-015-03	Diphenhydramine HCl and Zinc Acetate	88 mL in 1 CANISTER	AEROSOL, SPRAY	88		9

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ZINC ACETATE	ACTIVE INGREDIENT	FM5526K07A	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ZINC CATION	ACTIVE MOIETY	13S1S8SF37	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ALCOHOL	INACTIVE INGREDIENT	3K9958V90M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ALOE VERA LEAF	INACTIVE INGREDIENT	ZY81Z83H0X	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
TROMETHAMINE	INACTIVE INGREDIENT	023C2WHX2V	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49035-015	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	8	Current NDC, Legacy NDC, 1 package rows	20241109_709c3bb8-5b36-4823-941a-45ddb3e431c4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 133 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
TheraCare 4% Lidocaine Cream	LIDOCAINE HYDROCHLORIDE	Veridian Healthcare	c808aa05-9d49-cc9f-e053-2a95a90a50f3	2024-05-21	Warnings	Exact identifier application number: M017
TheraCare 4% Lidocaine and 1% Menthol Cream	MENTHOL AND LIDOCAINE	Veridian Healthcare	c80ba251-91a5-0858-e053-2995a90a9cff	2024-05-21	Warnings	Exact identifier application number: M017
HealthWise Menthol Roll-On	MENTHOL	Veridian Healthcare	102d57a5-6449-f825-e063-6294a90a8844	2024-05-21	Warnings	Exact identifier application number: M017
SAFLY Burn	LIDOCAINE HYDROCHLORIDE	Nantong Health & Beyond Hygienic Products Inc.	3aca2568-d10f-4b14-861b-6c741c106829	2024-05-17	Warnings	Exact identifier application number: M017
HealthWise Menthol 4% Roll-On	MENTHOL	Veridian Healthcare	1894ef00-ba05-0e02-e063-6394a90ab982	2024-05-16	Warnings	Exact identifier application number: M017
Leader Poison Ivy Wash	PRAMOXINE HYDROCHLORIDE LOTION	Cardinal Health, 110 dba Leader	81f2ecb0-c3ce-d2f8-e053-2a91aa0add0c	2024-05-13	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Oil Aromatic	CAMPHOR, MENTHOL, METHYL SALICYLATE	Borden Company (Private) Limited	0e808f89-62dc-3790-e063-6394a90a2351	2024-05-13	Warnings	Exact identifier application number: M017
Walgreens Lidocaine Plus Cream	BENZYL ALCOHOL AND LIDOCAINE HYDROCHLORIDE	Walgreens Company	e33e0097-31d6-8083-e053-2a95a90af5d2	2024-05-09	Warnings	Exact identifier application number: M017
Professional Therapy MuscleCare Pro Pain Relieving Cold Gel	CAMPHOR, MENTHOL	ACTIVE AND INNOVATIVE, LLC	1794c512-5f42-4ec3-e063-6394a90a87cd	2024-05-03	Warnings	Exact identifier application number: M017
Professional Therapy MuscleCare Pro	MENTHOL AND CAMPHOR	ACTIVE AND INNOVATIVE, LLC	17961a84-6bee-c75f-e063-6394a90af576	2024-05-03	Warnings	Exact identifier application number: M017
Aspercreme with Lidocaine Pain Relieving Creme	LIDOCAINE HYDROCHLORIDE	Chattem, Inc.	d5da67c3-c2ec-4e3e-abe9-cc862dcfc8bd	2024-05-01	Warnings	Exact identifier application number: M017
Lidocaine HCl 4 Percent	LIDOCAINE HYDROCHLORIDE	ARI BRANDS, LLC	81aff5c5-91c0-4173-a432-d20115613580	2024-04-30	Warnings	Exact identifier application number: M017
HealthWise 3x Medicated Pain Relief Patch 120 Bulk	CAMPHOR,MENTHOL, METHYL SALICYLATE	Veridian Healthcare	17545078-05e1-9338-e063-6394a90a678c	2024-04-30	Warnings	Exact identifier application number: M017
Professional Therapy MuscleCare Pro Roll-on	CAMPHOR, MENTHOL	ACTIVE AND INNOVATIVE, LLC	1755ec89-c404-1c17-e063-6394a90ab9fb	2024-04-30	Warnings	Exact identifier application number: M017
PAIN RELIEF Gel-Roll On	MENTHOL	Shanghai Chuangshi Medical Technology (Group) Co., Ltd.	f0bc2a14-6bda-428c-e053-2995a90a4ced	2024-04-29	Warnings	Exact identifier application number: M017
PAIN RELIEF Gel-Tube	MENTHOL	Shanghai Chuangshi Medical Technology (Group) Co., Ltd.	f0bec1d4-2e18-4519-e053-2a95a90a1bbb	2024-04-29	Warnings	Exact identifier application number: M017
THERAPLEX AIM Anti-Itch Moisturizing	HYDROCORTISONE	THERAPLEX, LLC	d1b231b6-cc9f-488a-9121-501831473772	2024-04-27	Warnings	Exact identifier application number: M017
HYDROCORTISONE	HYDROCORTISONE ACETATE	JHK Inc dba American Safety & First Aid	64adc8d0-7ca4-4c1a-813f-f1df47e916f2	2024-04-25	Warnings	Exact identifier application number: M017
HealthWise Lidocaine Plus Cream	BENZYL ALCOHOL, LIDOCAINE HYDROCHLORIDE	Veridian Healthcare	16f26249-b508-2c6e-e063-6394a90a265b	2024-04-25	Warnings	Exact identifier application number: M017
Hydrocortisone Cream with Aloe	HYDROCORTISONE	Cardinal Health 110 dba LEADER	16f2f3cb-4611-5867-e063-6394a90af107	2024-04-25	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE
FM5526K07A	ZINC ACETATE	5970-45-6	ZINC ACETATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1053138	diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Spray	PSN	709c3bb8-5b36-4823-941a-45ddb3e431c4	9
1053138	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray	SCD	709c3bb8-5b36-4823-941a-45ddb3e431c4	9
1053138	diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Spray	SY	709c3bb8-5b36-4823-941a-45ddb3e431c4	9

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
49035-015-03	49035001503	88 mL in 1 CANISTER (49035-015-03)	88 ml	2013-03-03	2026-10-31	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Equate Extra Strength Anti-Itch Continuous Spray	Wal-Mart Stores, Inc.	2025-06-27	HUMAN OTC DRUG LABEL	9