Diphenhydramine HCl and Zinc Acetate

Product NDC: 49035-015
11-digit product format: 490350015
Labeler code: 49035
Product ID: 49035-015_38917a94-449f-7050-e063-6394a90a0245
Type: HUMAN OTC DRUG
Nonproprietary name: Anti-Itch Continuous Spray
Dosage form: AEROSOL, SPRAY
Route: TOPICAL
Labeler: Wal-Mart Stores, Inc.
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2013-03-03
Marketing end: 2026-10-31
Substance: DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
Active strength: 1.5; .075 g/88mL; g/88mL
Pharmacologic classes: Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Diphenhydramine HCl and Zinc Acetate

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	1.5 g/88mL
ZINC ACETATE	.075 g/88mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup
FM5526K07A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1053138	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
709c3bb8-5b36-4823-941a-45ddb3e431c4	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
77dc03a4-fbfc-e6a3-fe95-285bbae40d75	Product name	2	20250814
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
49035-015-03	Diphenhydramine HCl and Zinc Acetate	88 mL in 1 CANISTER	AEROSOL, SPRAY	88		9

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ZINC ACETATE	ACTIVE INGREDIENT	FM5526K07A	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ZINC CATION	ACTIVE MOIETY	13S1S8SF37	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ALCOHOL	INACTIVE INGREDIENT	3K9958V90M	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
ALOE VERA LEAF	INACTIVE INGREDIENT	ZY81Z83H0X	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
TROMETHAMINE	INACTIVE INGREDIENT	023C2WHX2V	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49035-015	DIPHENHYDRAMINE HCL AND ZINC ACETATE (ANTI-ITCH CONTINUOUS SPRAY) AEROSOL, SPRAY [WAL-MART STORES, INC.]	8	Current NDC, Legacy NDC, 1 package rows	20241109_709c3bb8-5b36-4823-941a-45ddb3e431c4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 30 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
RICHTOFIT RAPID ACTIVE ARTHRITIS	MENTHOL AND CAMPHOR	RICHTOFIT LIMITED LIABILITY COMPANY	4b1cdab1-3e50-4ec3-e063-6394a90af75e	2026-03-12	Warnings	Exact identifier application number: M017
5Kind DMSO 4 Lidocaine HCl Pain Relieving	LIDOCAINE HYDROCHLORIDE, MENTHOL	5KIND TRADING LTD	67d8d045-7fa0-46c2-8072-645d8823903b	2026-03-11	Warnings	Exact identifier application number: M017
Rapid Relief	PAIN RELIEF PATCH LIDOCAINE 4%	RAPID AID VIET NAM COMPANY LIMITED	4ca541b4-7afe-77c5-e063-6294a90ad692	2026-03-10	Warnings	Exact identifier application number: M017
Lidocaine Cream, 4%	LIDOCAINE	IPG PHARMACEUTICALS, INC.	7775bfdd-7eac-4f09-b83f-fc4a16a24558	2026-03-10	Warnings	Exact identifier application number: M017
MENTHOL, CAMPHOR	MENTHOL, CAMPHOR	CHEMCO CORPORATION	4c989283-9a27-e8d2-e063-6294a90a8bfa	2026-03-09	Warnings	Exact identifier application number: M017
Prequel Anti-Itch Solution Medicated Calming	MEDICATED CALMING LOTION	The Center Brands, LLC	419fa45b-992b-676e-e063-6394a90add81	2026-03-09	Warnings	Exact identifier application number: M017
Careland Lidocaine 4 Plus Menthol Pain Relieving Gel Patches for back, neck shoulders knees and elbows with border	LIDOCAINE, MENTHOL	Planet (Anhui) Pharmaceutical Co., Ltd.	1fda69f7-2bb6-42fc-bcef-677e7b3d7f01	2026-03-09	Warnings	Exact identifier application number: M017
Careland Lidocaine 4 plus menthol pain relieving gel-patches with border for knee	MENTHOL, LAUROCAPRAM	Planet (Anhui) Pharmaceutical Co., Ltd.	7577625c-87eb-4639-aeab-8a2ab97033fd	2026-03-09	Warnings	Exact identifier application number: M017
Careland Lidocaine Pain Relieving	LIDOCAINE	Planet (Anhui) Pharmaceutical Co., Ltd.	7de99b81-b3b3-49f1-8aa7-2ff42e1b46a4	2026-03-09	Warnings	Exact identifier application number: M017
Rapid Relief	PAIN RELIEF PATCH LIDOCAINE 4%	RAPID AID VIET NAM COMPANY LIMITED	4ca35030-958c-8f62-e063-6294a90a4d63	2026-03-09	Warnings	Exact identifier application number: M017
Welmate Lidocaine Pain Relieving Patch	LIDOCAINE	YYBA Corp	cff71b75-fc4e-29ac-e053-2995a90abd50	2026-03-06	Warnings	Exact identifier application number: M017
Heal and Rescue Bunion Pain Relief	LIDOCAINE HCL, MENTHOL	Rooftop Consumer Health, Inc	4c60d4d3-e0a9-6f93-e063-6394a90a16af	2026-03-06	Warnings	Exact identifier application number: M017
JUST CBD - PAIN RELIEF	MENTHOL, CAMPHOR	Just Brands LLC	4c493c0b-c58e-cb56-e063-6394a90a9395	2026-03-05	Warnings	Exact identifier application number: M017
Hug a BooBoo Medicated booboo Wipes	BENZOCAINE	Lights Medical Manufacture Co., Ltd.	509aaafc-2ef7-4205-818c-7ff5b146e159	2026-03-04	Warnings	Exact identifier application number: M017
CVS Foot Pain	LIDOCAINE HYDROCHLORIDE	CVS Pharmacy	4c3350c3-2e3e-093c-e063-6394a90a3475	2026-03-04	Warnings	Exact identifier application number: M017
Game On Sport	MENTHOL	Natural Essentials, Inc	4c3411dc-5378-bd93-e063-6394a90a8406	2026-03-04	Warnings	Exact identifier application number: M017
Hydrocortisone 1%	HYDROCORTISONE	Trifecta Pharmaceuticals Usa Llc	f4d4a56b-b4b7-9a07-e053-2a95a90ad853	2026-03-04	Warnings	Exact identifier application number: M017
Hydrocortisone 1%	HYDROCORTISONE	Trifecta Pharmaceuticals Usa Llc	9987165c-1a0f-dd57-e053-2a95a90ae735	2026-03-04	Warnings	Exact identifier application number: M017
Walgreens Unscented Pain Relieving	LIDOCAINE HYDROCHLORIDE, BENZYL ALCOHOL	Walgreen Co.	41eadb4f-2ca5-42a1-e063-6294a90ab4e2	2026-03-04	Warnings	Exact identifier application number: M017
Careland Pain Relief Patch Plus	LIDOCAINE	Planet (Anhui) Pharmaceutical Co., Ltd.	d55d8a9e-ed2b-4c9b-9ecb-6ec1fd43c9e3	2026-03-04	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE
FM5526K07A	ZINC ACETATE	5970-45-6	ZINC ACETATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1053138	diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Spray	PSN	709c3bb8-5b36-4823-941a-45ddb3e431c4	9
1053138	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray	SCD	709c3bb8-5b36-4823-941a-45ddb3e431c4	9
1053138	diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Spray	SY	709c3bb8-5b36-4823-941a-45ddb3e431c4	9

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
49035-015-03	49035001503	88 mL in 1 CANISTER (49035-015-03)	88 ml	2013-03-03	2026-10-31	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Equate Extra Strength Anti-Itch Continuous Spray	Wal-Mart Stores, Inc.	2025-06-27	HUMAN OTC DRUG LABEL	9