Home NDC 49035-433 Headache Relief
Product NDC 49035-433
11-digit product format 490350433
Labeler code 49035
Product ID 49035-433_a5077198-1083-408b-9727-b89909de0558
Type HUMAN OTC DRUG
Nonproprietary name Acetaminophen, Aspirin and Caffeine
Dosage form TABLET, FILM COATED
Route ORAL
Labeler Wal-Mart Stores Inc
Application M013
Marketing category OTC MONOGRAPH DRUG
Marketing start 2008-03-13
Substance ACETAMINOPHEN; ASPIRIN; CAFFEINE
Active strength 250; 250; 65 mg/1; mg/1; mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Methylxanthine [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Xanthines [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Headache Relief
Brand name suffix Extra Strength
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength ACETAMINOPHEN 250 mg/1 ASPIRIN 250 mg/1 CAFFEINE 65 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 3 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 362O9ITL9D Internal UNII lookup R16CO5Y76E Internal UNII lookup 3G6A5W338E Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 308297 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 49035-433-06 Headache ReliefExtra Strength 2 in 1 CARTON TABLET, FILM COATED 2 17 49035-433-08 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 17 49035-433-08 Headache ReliefExtra Strength 24 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 24 17 49035-433-12 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 17 49035-433-85 Headache ReliefExtra Strength 200 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 200 17
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded ACETAMINOPHEN ACTIVE INGREDIENT 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 ASPIRIN ACTIVE INGREDIENT R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 CAFFEINE ACTIVE INGREDIENT 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 ACETAMINOPHEN ACTIVE MOIETY 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 ASPIRIN ACTIVE MOIETY R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 CAFFEINE ACTIVE MOIETY 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 CROSPOVIDONE INACTIVE INGREDIENT 68401960MK HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 HYPROMELLOSES INACTIVE INGREDIENT 3NXW29V3WO HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 POVIDONES INACTIVE INGREDIENT FZ989GH94E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 SODIUM LAURYL SULFATE INACTIVE INGREDIENT 368GB5141J HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 STEARIC ACID INACTIVE INGREDIENT 4ELV7Z65AP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 1
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 49035-433 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WAL-MART STORES INC] 16 Current NDC, Legacy NDC, 5 package rows 20250501_9b1201af-c802-4e19-b192-bbbf34367db4.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 23 of 79 · 1,579 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Aspirin 81 mg ASPIRIN HYVEE INC 3e602287-565e-a5b9-e063-6294a90abc17 2026-01-13 Warnings Exact identifier application number: M013 ASPIRIN DELAYED RELEASE 81MG ASPIRIN DELAYED RELEASE 81MG Farmacias De Similares TX LLC 3a8a3efc-f0b3-411c-e063-6394a90a84b7 2026-01-13 Warnings Exact identifier application number: M013 Chewable Aspirin 81 mg ASPIRIN HYVEE INC 459f749f-9d23-8752-e063-6394a90a8c81 2026-01-13 Warnings Exact identifier application number: M013 ASPIRIN 325 mg ASPIRIN HYVEE INC 459d01df-6ff6-cff6-e063-6394a90ab35c 2026-01-13 Warnings Exact identifier application number: M013 Pain Terminator Extra Strength Pain Relief CAFFEINE, ACETAMINOPHEN, ASPIRIN Wildman Business Group 8ffb02d9-92df-4d2f-a367-1c71490807fb 2026-01-12 Warnings Exact identifier application number: M013 Aspirin Packs ASPIRIN Sina Health Inc 2865a2c3-53fc-ab9a-e063-6394a90a1418 2026-01-12 Warnings Exact identifier application number: M013 Acetaminophen ACETAMINOPHEN PD-Rx Pharmaceuticals, Inc. 64696f65-415e-4ce1-a5b3-70662fbcb002 2026-01-12 Warnings Exact identifier application number: M013 Aspirin enteric coated low dose ASPIRIN Walgreen Company 186a6270-e3de-4499-88a4-5f723fee3e34 2026-01-12 Warnings Exact identifier application number: M013 Tension Headache ACETAMINOPHEN, CAFFEINE Cardinal Health 110, LLC. DBA Leader 96684e3f-a13e-49c3-b437-d2627e528a2d 2026-01-12 Warnings Exact identifier application number: M013 Low Dose Aspirin ASPIRIN Family Dollar Services Inc d35d798e-76f1-454d-86f6-ad11c3bf17d8 2026-01-12 Warnings Exact identifier application number: M013 Xpect Acetaminophen ACETAMINOPHEN Cintas Corporation f4aed854-730e-493d-b523-122156e08dde 2026-01-09 Warnings Exact identifier application number: M013 Aspirin ASPIRIN INVAHEALTH INC e5e8a8d5-9174-7975-e053-2a95a90a9aa6 2026-01-08 Warnings Exact identifier application number: M013 Xpect Cold Relief ACETAMINOPHEN GUAIFENESEIN PHENYLEPHRINE HCL Cintas Corporation 02391d55-32b2-4083-9315-98e9b3650c55 2026-01-08 Warnings Exact identifier application number: M013 pain relief back and body EXTRA STRENGTH ASPIRIN, CAFFEINE Rite Aid Corporation a71392c8-3f5b-4d00-baba-a4055ed68bc1 2026-01-07 Warnings Exact identifier application number: M013 Pain Reliever Extra Strength ACETAMINOPHEN L.N.K. International, Inc. 8fed703a-9de2-4c76-a783-fcf004f9b890 2026-01-07 Warnings Exact identifier application number: M013 Aspirin ASPIRIN Amerisource Bergen c3099892-a8cd-4574-a6f9-041e59e2feae 2026-01-07 Warnings Exact identifier application number: M013 Bactimicina Childrens Pain and Fever ACETAMINOPHEN DLC Laboratories, Inc. bdade270-d813-4178-b594-4951632b6839 2026-01-07 Warnings Exact identifier application number: M013 Goodmeds Extra Strength Pain Relief PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE Cabinet Health P.B.C. 02c60967-46d7-49b7-82be-bc3c5fd36484 2026-01-06 Warnings Exact identifier application number: M013 Childrens Acetaminophen ACETAMINOPHEN ARMY AND AIR FORCE EXCHANGE SERVICE a73f8217-9eae-4e2a-b29c-7de3861d0e37 2026-01-06 Warnings Exact identifier application number: M013 Pain Relief Acetaminophen PM ACETAMINOPHEN AND DIPHENHYDRAMINE HCL Rite Aid Corporation f77f0120-4042-4b11-ba9c-cd35e1cd0bee 2026-01-05 Warnings Exact identifier application number: M013
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 49035-433-06 49035043306 2 BOTTLE in 1 CARTON (49035-433-06) > 100 TABLET, FILM COATED in 1 BOTTLE (49035-433-12) 2 bottle 2008-03-13 0000-00-00 No No Current 49035-433-08 49035043308 1 BOTTLE, PLASTIC in 1 CARTON (49035-433-08) / 24 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2008-03-13 0000-00-00 No No Current 49035-433-12 49035043312 100 in 1 BOTTLE, PLASTIC Historical 49035-433-85 49035043385 200 TABLET, FILM COATED in 1 BOTTLE (49035-433-85) 2008-03-13 0000-00-00 No No Current