CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25

Product NDC: 49527-080
11-digit product format: 495270080
Labeler code: 49527
Product ID: 49527-080_0818396d-cc21-00ac-e063-6394a90a5d82
Type: HUMAN OTC DRUG
Nonproprietary name: TITANIUM DIOXIDE, ZINC OXIDE
Dosage form: LIQUID
Route: TOPICAL
Labeler: CLINIQUE LABORATORIES LLC
Application: M020
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-09-24
Substance: TITANIUM DIOXIDE; ZINC OXIDE
Active strength: 24; 59 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	49527-080	49527-080-03	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 27 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Code	Status	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-27 05:24 UTC · source 2025-02-26	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`f268b84574a6…`	`26285f5ac5df…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`302b2466d912…`	`e7b80fea0513…`
2025-02-01 13:13 UTC · source 2025-01-31	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`f764e8902f78…`	`92046438deef…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-17	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`68b1e3bced9e…`	`98a755eb8bc6…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-29 20:42 UTC · source 2024-11-29	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`05c55d027831…`	`ca05dca9dc4c…`
2024-11-29 20:42 UTC · source 2024-11-29	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`05c55d027831…`	`ca05dca9dc4c…`
2024-11-09 02:36 UTC · source 2024-11-08	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`48b4f40e6753…`	`c7c7a00d2afa…`
2024-11-09 02:36 UTC · source 2024-11-08	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`48b4f40e6753…`	`c7c7a00d2afa…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-09 02:27 UTC · source 2024-10-08	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`27f29a85d7e4…`	`1372111e901f…`
2024-10-09 02:27 UTC · source 2024-10-08	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`27f29a85d7e4…`	`1372111e901f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`8d62ce987f31…`	`9fe9ef23e30d…`
2024-07-10 04:00 UTC · source 2024-07-09	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`8d62ce987f31…`	`9fe9ef23e30d…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	49527-080-03	D	Discontinued by firm	excluded / ndc_excluded.zip	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:11 UTC · source 2024-05-28	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`d1e113ab4d42…`	`063ee3eb0a1d…`
2024-05-28 21:11 UTC · source 2024-05-28	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`d1e113ab4d42…`	`063ee3eb0a1d…`
2024-05-15 03:51 UTC · source 2024-05-14	unfinished product	product		UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`50b4072663b7…`	`eae3003ed65e…`
2024-05-15 03:51 UTC · source 2024-05-14	unfinished package	package	49527-080-00	UNFINISHED	Active or certified unfinished drug listing	unfinished / ndc_unfinished.zip	`50b4072663b7…`	`eae3003ed65e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
TITANIUM DIOXIDE	24 mg/mL
ZINC OXIDE	59 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
15FIX9V2JP	Internal UNII lookup
SOI2LOH54Z	Internal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
884abba1-891d-4c3c-b203-38a5a8a57756	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
7dea7767-9f52-b60a-5435-33cb9cc28bae	Product name	4	20250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4	Product name	7	20250116
0ca83774-3f79-b837-5d6f-c210102f3bc8	Product name	6	20250114
cb89b86a-369e-4204-8910-ae797c503af3	Product name	1	20230706
41b814f3-0166-1c53-c9ef-a0794c7daf9d	Product name	3	20221110
a590be26-846c-8659-a5a1-fb25907965dc	Product name	2	20221110
2dc76302-91c0-4c35-ad78-99adfb049c4b	Product name	1	20200603
d4880ace-a516-8c47-8dfd-73a4ba5887d7	Product name	2	20180830
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
e6065d4b-5ae1-476f-a40e-f2851cbb5d2b	Product name	2	20180221
f212291f-05fe-9603-fc7e-bd73e38ce1e6	Product name	2	20161129
182f9ab4-4ab5-c449-200f-87ce2ce8e550	Product name	2	20151105
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
332e86c3-7875-ca6e-f934-2206d2b31996	Product name	1	20140508
56625fcc-aa34-9d30-d0e9-1c1beb37ea21	Product name	1	20140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092	Product name	1	20140508
96c2be53-8e44-452d-56a2-d255b2f1af2d	Product name	1	20140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44	Product name	1	20140508
d223c173-c39b-d764-47d4-d671d3088815	Product name	1	20140508
e01133ad-4dcd-c7f3-454b-2ff569ee160a	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
49527-080-01	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	30 mL in 1 BOTTLE	LIQUID	30	13
49527-080-01	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	1 in 1 CARTON	LIQUID	1	13
49527-080-02	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	1 in 1 CARTON	LIQUID	1	13
49527-080-02	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	5 mL in 1 TUBE	LIQUID	5	13
49527-080-03	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	0.2 mL in 1 PACKET	LIQUID	0.2	13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49527-080	CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25 (TITANIUM DIOXIDE, ZINC OXIDE) LIQUID [CLINIQUE LABORATORIES LLC]	13	Current NDC, Legacy NDC, 5 package rows	20231020_884abba1-891d-4c3c-b203-38a5a8a57756.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 62 of 357 · 7,139 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
e.l.f. Wake the E.L.F. Up Skincare Set	AVOBENZONE, OCTISALATE, OCTOCRYLENE, HOMOSALATE	e.l.f. Cosmetics, Inc	4b20c56a-3e91-3419-e063-6294a90ad361	2026-02-18	Warnings	Exact identifier application number: M020
Dermatone Mineral SPF 30	ZINC OXIDE 20%	Dermatone Labs LLC	26e3209f-cb5c-484e-9b2e-74dc397d4790	2026-02-18	Warnings	Exact identifier application number: M020
SHISEIDO ESSENTIAL ENERGY HYDRATING DAY	HOMOSALATE, OCTOCRYLENE, OCTISALATE, AND AVOBENZONE	SHISEIDO AMERICAS CORPORATION	8b88039a-09fe-458b-b80f-49cde49b6595	2026-02-17	Warnings	Exact identifier application number: M020
cle de peau BEAUTE SYNACTIF DAYTIME MOISTURIZER ENRICHED n	AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE	SHISEIDO AMERICAS CORPORATION	f3729d0b-e601-48bb-9907-1d6e3ab31996	2026-02-17	Warnings	Exact identifier application number: M020
Luminesce Daily Moisturizing Complex	AVOBENZONE, OCTINOXATE, OCTISALATE, OCTOCRYLENE	Velovita Inc.	4b0c2213-8667-be6f-e063-6394a90a5e86	2026-02-17	Warnings	Exact identifier application number: M020
Sport Sunscreen SPF 30	AVOBENZONE, HOMOSALATE, OCTISALATE	Valu Merchandisers Company	e168f8e8-22d0-4a60-b9f9-dec9d0fab3f1	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M020
Sunscreen for Kids SPF 50	AVOBENZONE, HOMOSALATE, OCTISALATE	Valu Merchandisers Company	cfc3b202-6511-450a-b3c1-2d8e8ebc070d	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M020
Sport Sunscreen SPF 70	AVOBENZONE, HOMOSALATE, OCTISALATE	Valu Merchandisers Company	5a8af0ea-b31c-456a-bc23-31e2473ca75a	2026-02-16	Warnings, Adverse reactions	Exact identifier application number: M020
Sparms 100% Organic Face Sunscreen	ZINC OXIDE SUNSCREEN	VEGANIC SKN LIMITED	4ae6b187-142b-e4a6-e063-6294a90af365	2026-02-15	Warnings	Exact identifier application number: M020
Lotus Harmony - Quinn Shield Sunscreen SPF50	ZINC OXIDE SUNSCREEN	VEGANIC SKN LIMITED	4ae73d23-1118-716c-e063-6394a90a68c7	2026-02-15	Warnings	Exact identifier application number: M020
Avebonzone, Homosalate, Octisalate	AVEBONZONE, HOMOSALATE, OCTISALATE	Amazon.com Services LLC	4ab542aa-bd05-ba7a-e063-6294a90ae584	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M020
Beauty Hydrating	HOMOSALATE, ZINC OXIDE	Topco Associates LLC	6e88ccc8-8576-4573-8a5b-28e64008a349	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M020
Wotnot Naturals Natural Zinc Sunscreen SPF 30	ZINC OXIDE	ECOdirect Pty Ltd (Trading as Wotnot Naturals)	4ab759ae-0c1c-bddc-e063-6394a90a1d09	2026-02-13	Warnings	Exact identifier application number: M020
Wotnot Naturals Natural Zinc Sunscreen SPF 30	ZINC OXIDE	ECOdirect Pty Ltd (Trading as Wotnot Naturals)	4ab83b34-9376-d169-e063-6394a90a18cd	2026-02-13	Warnings	Exact identifier application number: M020
Homosalate, Octisalate, Zinc oxide	HOMOSALATE, OCTISALATE, ZINC OXIDE	Topco Associates LLC	48fb9a3c-c058-ce71-e063-6294a90aaf1e	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M020
Ambi Even and Clear Facial Moisturizer	HOMOSALATE 15%, OCTISALATE 5%, OCTOCRYLENE 3%, AVOBENZONE 3%	73453-112	469440e9-bf47-bebd-e063-6294a90acca2	2026-02-12	Warnings	Exact identifier application number: M020
Intelligent Defense Mineral Sunscreen	ZINC OXIDE	GLO PHARMA	4ab664aa-5f0c-7ddb-e063-6294a90a9753	2026-02-12	Warnings	Exact identifier application number: M020
Sky and Sol Sports Sunscreen	ZINC OXIDE	Delta Ecommerce LLC	4dd054cd-8f53-4210-e063-6394a90ade27	2026-02-12	Warnings	Exact identifier application number: M020
Sky and Sol Kids and Babies Sunscreen	ZINC OXIDE	Delta Ecommerce LLC	4de67653-ab31-c6b2-e063-6394a90a7e8c	2026-02-12	Warnings	Exact identifier application number: M020
Eva Claire Natural Professional Sunscreen	AVOBENZONE, HOMOSALATE, OCTOCRYLENE, OCTISALATE	Eva Claire Cosmetics Co., Ltd.	4a870452-cac2-4d2c-e063-6294a90abb07	2026-02-11	Warnings	Exact identifier application number: M020

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
15FIX9V2JP	TITANIUM DIOXIDE	13463-67-7	TITANIUM DIOXIDE
SOI2LOH54Z	ZINC OXIDE	1314-13-2	ZINC OXIDE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
49527-080-01	49527008001	1 BOTTLE in 1 CARTON (49527-080-01) / 30 mL in 1 BOTTLE	1 bottle	2020-09-24	0000-00-00	No	No	Current
49527-080-02	49527008002	1 TUBE in 1 CARTON (49527-080-02) / 5 mL in 1 TUBE	1 tube	2022-06-06	0000-00-00	No	No	Current
49527-080-03	49527008003	.2 mL in 1 PACKET (49527-080-03)		2022-11-30	0000-00-00	Yes	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
CLINIQUE EVEN BETTER CLINICAL SERUM FOUNDATION BROAD SPECTRUM SPF 25	CLINIQUE LABORATORIES LLC \| Estee Lauder Companies Inc. \| Estee Lauder Cosmetics Ltd.	2023-10-19	HUMAN OTC DRUG LABEL	13