DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35

Product NDC: 49527-222
11-digit product format: 495270222
Labeler code: 49527
Product ID: 49527-222_486e9b0e-bd13-8469-e063-6394a90a7ba2
Type: HUMAN OTC DRUG
Nonproprietary name: AVOBENZONE,HOMOSALATE,OCTISALATE,OCTOCRYLENE
Dosage form: CREAM
Route: TOPICAL
Labeler: CLINIQUE LABORATORIES LLC
Application: M020
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2025-03-31
Substance: HOMOSALATE; OCTISALATE; AVOBENZONE; OCTOCRYLENE
Active strength: 70; 45; 30; 50 mg/mL; mg/mL; mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
HOMOSALATE	70 mg/mL
OCTISALATE	45 mg/mL
AVOBENZONE	30 mg/mL
OCTOCRYLENE	50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
V06SV4M95S	Internal UNII lookup
4X49Y0596W	Internal UNII lookup
G63QQF2NOX	Internal UNII lookup
5A68WGF6WM	Internal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
316bf6f8-7d30-2560-e063-6294a90afb8a	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
77dc03a4-fbfc-e6a3-fe95-285bbae40d75	Product name	2	20250814

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
49527-222-01	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35	1 in 1 CARTON	CREAM	1	3
49527-222-01	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35	75 mL in 1 BOTTLE	CREAM	75	3
49527-222-02	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35	50 mL in 1 TUBE	CREAM	50	3
49527-222-02	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35	1 in 1 CARTON	CREAM	1	3
49527-222-03	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35	30 mL in 1 TUBE	CREAM	30	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49527-222	DRAMATICALLY DIFFERENT MOISTURIZING LTN BROAD SPECTRUM SPF35 (AVOBENZONE,HOMOSALATE,OCTISALATE,OCTOCRYLENE) CREAM [CLINIQUE LABORATORIES LLC]	2	Current NDC, 5 package rows	20250406_316bf6f8-7d30-2560-e063-6294a90afb8a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 142 of 353 · 7,041 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Foam Weightless Sunscreen Non-Tinted Drytouch NT	TITANIUM DIOXIDE, ZINC OXIDE	Cutis Wellness Dermatology And Dermatopathology PLLC	335ec22c-6a9a-c4d1-e063-6394a90ac0b0	2025-12-09		Exact identifier application number: M020
Mineral Sunscreen Moisturizing Non-Tinted	ZINC OXIDE	Cutis Wellness Dermatology And Dermatopathology PLLC	3360a208-5f17-a74b-e063-6294a90a13e1	2025-12-09		Exact identifier application number: M020
Tinted Mineral Sunscreen	TITANIUM DIOXIDE, ZINC OXIDE	Lily Lee, MD	323356ea-31a0-6ff0-e063-6294a90a135c	2025-12-09		Exact identifier application number: M020
Non-Tinted Mineral Sunscreen	TITANIUM DIOXIDE, ZINC OXIDE	Lily Lee, MD	32330376-5db0-202b-e063-6294a90add15	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Untinted	ZINC OXIDE	Lily Lee, MD	32354468-94a2-604b-e063-6394a90adfb5	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Tinted	ZINC OXIDE	Lily Lee, MD	32346536-f542-ef0f-e063-6394a90a0464	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Mineral Stick Untinted	TITANIUM DIOXIDE, ZINC OXIDE	Lily Lee, MD	3234b498-5b56-55f4-e063-6294a90a9b87	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Tinted	ZINC OXIDE	Lily Lee, MD	3235a696-92aa-788c-e063-6394a90a0149	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Mineral Stick Tinted	TITANIUM DIOXIDE, ZINC OXIDE	Lily Lee, MD	32351db0-884c-8fa0-e063-6294a90acba2	2025-12-09		Exact identifier application number: M020
Sunscreen Plus Untinted	ZINC OXIDE	Lily Lee, MD	3235786d-7ba9-c9ab-e063-6294a90a7f2e	2025-12-09		Exact identifier application number: M020
Tinted Mineral Sunscreen 20% Zinc Oxide	ZINC OXIDE	INTEGRATIVE AESTHETICS BOSTON, LLC	31416d04-2d6f-7cf9-e063-6294a90a9806	2025-12-09	Warnings	Exact identifier application number: M020
Matte Invisible Mineral Sunscreen Non-Tinted	ZINC OXIDE	INTEGRATIVE AESTHETICS BOSTON, LLC	3143968a-096e-b9ac-e063-6294a90ada0d	2025-12-09	Warnings	Exact identifier application number: M020
Daily Mineral Sunscreen 20% Zinc Oxide	ZINC OXIDE	INTEGRATIVE AESTHETICS BOSTON, LLC	314299b1-a78b-c1bd-e063-6294a90ab43b	2025-12-09	Warnings	Exact identifier application number: M020
Sheer Satin Mineral Sunscreen Tinted	TITANIUM DIOXIDE, ZINC OXIDE	INTEGRATIVE AESTHETICS BOSTON, LLC	3143d8b0-4af8-f52d-e063-6294a90a926b	2025-12-09	Warnings	Exact identifier application number: M020
Matte Invisible Mineral Sunscreen	ZINC OXIDE	INTEGRATIVE AESTHETICS BOSTON, LLC	3142ed0f-f379-f240-e063-6294a90a5303	2025-12-09	Warnings	Exact identifier application number: M020
Sheer Non-Tinted Mineral Sunscreen Stick	TITANIUM DIOXIDE, ZINC OXIDE	Face Collection, L.L.C.	33d83cfb-045d-141c-e063-6394a90a2e04	2025-12-09		Exact identifier application number: M020
First Aid Beauty FAB Ultra Light Mineral Sunscreen Broad Spectrum SPF 30	ZINC OXIDE	The Procter & Gamble Manufacturing Company	45875865-5e9c-d652-e063-6394a90ad5fa	2025-12-09	Warnings	Exact identifier application number: M020
Tinted Mineral Sunscreen	TITANIUM DIOXIDE, ZINC OXIDE	Maloney Plastic Surgery Skin Care, PLLC	316b7584-c782-fe9e-e063-6394a90a76fe	2025-12-09		Exact identifier application number: M020
Transparent Tinted Mineral Sunscreen Stick	TITANIUM DIOXIDE, ZINC OXIDE	Face Collection, L.L.C.	33dbfd9b-b90f-bb32-e063-6294a90af7dc	2025-12-09		Exact identifier application number: M020
Tinted Mineral Sunscreen	TITANIUM DIOXIDE, ZINC OXIDE	Maloney Plastic Surgery Skin Care, PLLC	316b46ac-6dde-72d1-e063-6294a90a03da	2025-12-09		Exact identifier application number: M020

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
V06SV4M95S	HOMOSALATE	118-56-9	HOMOSALATE
4X49Y0596W	OCTISALATE	118-60-5	OCTISALATE
G63QQF2NOX	AVOBENZONE	70356-09-1	AVOBENZONE
5A68WGF6WM	OCTOCRYLENE	6197-30-4	OCTOCRYLENE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
49527-222-01	49527022201	1 BOTTLE in 1 CARTON (49527-222-01) / 75 mL in 1 BOTTLE	1 bottle	2025-03-31	No	No	Current
49527-222-02	49527022202	1 TUBE in 1 CARTON (49527-222-02) / 50 mL in 1 TUBE	1 tube	2025-03-31	No	No	Current
49527-222-03	49527022203	30 mL in 1 TUBE (49527-222-03)	30 ml	2026-01-15	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
DRAMATICALLY DIFFERENT MOISTURIZING LOTION+ BROAD SPECTRUM SPF35	CLINIQUE LABORATORIES LLC \| Estee Lauder Companies Inc. \| Estee Lauder Cosmetics Ltd \| Estee Lauder Cosmetics Ltd. \| PALC	2026-01-15	HUMAN OTC DRUG LABEL	3