Mitosol

Product NDC
49771-002
11-digit product format
497710002
Labeler code
49771
Product ID
49771-002_ffbaf9a3-07ba-4b4f-ad79-d0ec5dcf84d7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
mitomycin
Dosage form
KIT
Labeler
Mobius Therapeutics LLC
Application
NDA022572
Marketing category
NDA
Marketing start
2012-02-08
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022572-001MITOSOLMITOMYCIN0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07

Orange Book patents#

Current patent rows page 1 of 1 · 5 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N022572-00181865112026-07-19Drug product2012-06-25
N022572-00192050752026-07-19Drug product2016-01-06
N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10
N022572-00178062652029-02-01Drug product2012-03-22
N022572-00196494282029-05-21U-20952017-06-09

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-0787673890dc5c…
2021-03-12 10:30 UTC2021-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07c0c555d07b60…
2019-12-14 00:12 UTC2019-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073f01610625f2…
2019-09-15 20:21 UTC2019-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07b00525d2431f…
2019-07-19 19:46 UTC2019-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073f0d92c62455…
2023-05-13 08:27 UTC2023-05N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07053a50430f4f…
2023-01-26 05:58 UTC2023-01N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022572-001MITOSOL0.2MG/VIALFOR SOLUTION / TOPICALRLD, RS2012-02-07e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 6 · 210 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N022572-00181865112026-07-19Drug product2012-06-25caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00192050752026-07-19Drug product2016-01-06caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00178062652029-02-01Drug product2012-03-22caaa826d4ba7…
2026-08-18 06:07:402026-07N022572-00196494282029-05-21U-20952017-06-09caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N022572-00181865112026-07-19Drug product2012-06-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00192050752026-07-19Drug product2016-01-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00178062652029-02-01Drug product2012-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022572-00196494282029-05-21U-20952017-06-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00181865112026-07-19Drug product2012-06-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00192050752026-07-19Drug product2016-01-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00178062652029-02-01Drug product2012-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022572-00196494282029-05-21U-20952017-06-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N022572-00181865112026-07-19Drug product2012-06-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00192050752026-07-19Drug product2016-01-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00178062652029-02-01Drug product2012-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022572-00196494282029-05-21U-20952017-06-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00181865112026-07-19Drug product2012-06-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00192050752026-07-19Drug product2016-01-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00178062652029-02-01Drug product2012-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022572-00196494282029-05-21U-20952017-06-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00181865112026-07-19Drug product2012-06-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00192050752026-07-19Drug product2016-01-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00178062652029-02-01Drug product2012-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022572-00196494282029-05-21U-20952017-06-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00181865112026-07-19Drug product2012-06-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00192050752026-07-19Drug product2016-01-0603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00178062652029-02-01Drug product2012-03-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022572-00196494282029-05-21U-20952017-06-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00181865112026-07-19Drug product2012-06-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00192050752026-07-19Drug product2016-01-062680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00195392412028-01-02U-2095Drug substance, Drug product2017-02-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00178062652029-02-01Drug product2012-03-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022572-00196494282029-05-21U-20952017-06-092680178bc6a6…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N022572-001ODE-212019-02-0774a2ff9319b5…
2019-12-14 00:12 UTC2019-12N022572-001ODE-212019-02-073f01610625f2…
2019-09-15 20:21 UTC2019-09N022572-001ODE-212019-02-07b00525d2431f…
2019-07-19 19:46 UTC2019-07N022572-001ODE-212019-02-07ea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Mitosol
Listing expiration
2026-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1244553Internal RxNorm lookup
1244558Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
244002c6-c61d-43fe-9326-072797113979Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
61a18a7f-d50a-4423-aa08-6a8f710ed5daProduct name720250722
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
1f4d6d8c-234a-4bf6-b123-695584719ba0Product name120200728
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
49771-002-01Mitosol1 in 1 TRAYKIT110
49771-002-03Mitosol3 in 1 CARTONKIT310

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
49771-002-01EA - Each49771-002cb571edc-741e-43e9-8fbb-232ee4982cc712012-07-24
49771-002-03EA - Each49771-002867c011f-739b-48b4-ac43-e71cd6e0586412012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ISOPROPYL ALCOHOLACTIVE INGREDIENTND2M416302MITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3
MitomycinACTIVE INGREDIENT50SG953SK6MITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3
ISOPROPYL ALCOHOLACTIVE MOIETYND2M416302MITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3
MitomycinACTIVE MOIETY50SG953SK6MITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3
mannitolINACTIVE INGREDIENT3OWL53L36AMITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3
waterINACTIVE INGREDIENT059QF0KO0RMITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
49771-002MITOSOL (MITOMYCIN) KIT [MOBIUS THERAPEUTICS LLC]10Current NDC, Legacy NDC, 2 package rows20250423_244002c6-c61d-43fe-9326-072797113979.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MitosolMITOMYCINMobius Therapeutics LLC244002c6-c61d-43fe-9326-0727971139792025-04-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 022572
application number: NDA022572
ndc (product): 49771-002

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1244553mitoMYcin 0.2 MG/ML Ophthalmic SolutionPSN244002c6-c61d-43fe-9326-07279711397910
1244558Mitosol 0.2 MG/ML Ophthalmic SolutionPSN244002c6-c61d-43fe-9326-07279711397910
1244558mitomycin 0.2 MG/ML Ophthalmic Solution [Mitosol]SBD244002c6-c61d-43fe-9326-07279711397910
1244553mitomycin 0.2 MG/ML Ophthalmic SolutionSCD244002c6-c61d-43fe-9326-07279711397910
1244558Mitosol 0.2 MG/ML Ophthalmic SolutionSY244002c6-c61d-43fe-9326-07279711397910

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
49771-002-01497710002011 in 1 TRAYHistorical
49771-002-03497710002033 TRAY in 1 CARTON (49771-002-03) / 1 KIT in 1 TRAY (49771-002-01) * 1 mL in 1 VIAL, SINGLE-USE * 1 mL in 1 SYRINGE, GLASS3 tray2012-02-080000-00-00NoNoCurrent