Amiloride Hydrochloride

Product NDC
49884-117
11-digit product format
498840117
Labeler code
49884
Product ID
49884-117_cee18f3c-6f68-46d0-9e69-72c504c5a798
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Amiloride Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Endo USA, Inc.
Application
ANDA070346
Marketing category
ANDA
Marketing start
1986-01-22
Substance
AMILORIDE HYDROCHLORIDE ANHYDROUS
Active strength
5 mg/1
Pharmacologic classes
Decreased Renal K+ Excretion [PE], Increased Diuresis [PE], Potassium-sparing Diuretic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A070346-001AMILORIDE HYDROCHLORIDEAMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A070346-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-2274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-2287673890dc5c…
2021-03-12 10:30 UTC2021-03A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-223f01610625f2…
2019-09-15 20:21 UTC2019-09A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22b00525d2431f…
2019-07-19 19:46 UTC2019-07A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-229b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-223f0d92c62455…
2023-05-13 08:27 UTC2023-05A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22053a50430f4f…
2023-01-26 05:58 UTC2023-01A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-223bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-223a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070346-001AMILORIDE HYDROCHLORIDE5MGTABLET / ORALABRS1986-01-22cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A070346-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070346-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A070346-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070346-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070346-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070346-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070346-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070346-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070346-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070346-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070346-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070346-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070346-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070346-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070346-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070346-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070346-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070346-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070346-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070346-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070346-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A070346-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070346-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070346-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070346-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A070346-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A070346-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070346-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070346-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070346-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070346-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070346-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070346-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070346-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A070346-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A070346-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070346-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070346-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070346-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070346-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Amiloride Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMILORIDE HYDROCHLORIDE ANHYDROUS5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7M458Q65S3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
977880Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e0cc2d44-436a-47e8-a890-589882fff4c4Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7954898a-d540-405e-aa1d-3553358552e5Product name120150812

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
49884-117-01Amiloride Hydrochloride100 in 1 BOTTLETABLET10011
49884-117-10Amiloride Hydrochloride1000 in 1 BOTTLETABLET100011

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
49884-117-01EA - Each49884-117144252bb-d636-4336-9640-7e82ae8c6edd12012-07-24
49884-117-10EA - Each49884-1173e010261-3856-4a92-87de-c6f93ddda7d712012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
AMILORIDE HYDROCHLORIDE ANHYDROUSACTIVE INGREDIENT7M458Q65S3AMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
AMILORIDEACTIVE MOIETY7DZO8EB0Z3AMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UAMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
COLLOIDAL SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4AMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GAMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
DIBASIC CALCIUM PHOSPHATE DIHYDRATEINACTIVE INGREDIENTO7TSZ97GEPAMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8AMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30AMILORIDE HYDROCHLORIDE TABLET [PAR PHARMACEUTICAL INC.]5
AMILORIDE HYDROCHLORIDE ANHYDROUSACTIVE INGREDIENT7M458Q65S3AMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
AMILORIDEACTIVE MOIETY7DZO8EB0Z3AMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
CALCIUM PHOSPHATE, DIBASIC, DIHYDRATEINACTIVE INGREDIENTO7TSZ97GEPAMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UAMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GAMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8AMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30AMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4AMILORIDE HYDROCHLORIDE TABLET [CARILION MATERIALS MANAGEMENT]2
AMILORIDE HYDROCHLORIDE ANHYDROUSACTIVE INGREDIENT7M458Q65S3AMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
AMILORIDEACTIVE MOIETY7DZO8EB0Z3AMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
CALCIUM PHOSPHATE, DIBASIC, DIHYDRATEINACTIVE INGREDIENTO7TSZ97GEPAMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UAMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GAMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8AMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30AMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4AMILORIDE HYDROCHLORIDE TABLET [GOLDEN STATE MEDICAL SUPPLY, INC.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
49884-117AMILORIDE HYDROCHLORIDE TABLET [ENDO USA, INC.]11Current NDC, Legacy NDC, 2 package rows20250109_e0cc2d44-436a-47e8-a890-589882fff4c4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amiloride HydrochlorideAMILORIDE HYDROCHLORIDEEndo USA, Inc.e0cc2d44-436a-47e8-a890-589882fff4c42024-11-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070346
application number: ANDA070346
ndc (product): 49884-117
Amiloride HydrochlorideAMILORIDE HYDROCHLORIDEBryant Ranch Prepack18d551a9-ffc7-4b14-adbd-92d84aa8e9662023-11-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070346
application number: ANDA070346

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
977880aMILoride HCl 5 MG Oral TabletPSN18d551a9-ffc7-4b14-adbd-92d84aa8e966103
977880amiloride hydrochloride 5 MG Oral TabletSCD18d551a9-ffc7-4b14-adbd-92d84aa8e966103
977880aMILoride HCl 5 MG Oral TabletPSNe0cc2d44-436a-47e8-a890-589882fff4c411
977880amiloride hydrochloride 5 MG Oral TabletSCDe0cc2d44-436a-47e8-a890-589882fff4c411
977880aMILoride HCl 5 MG Oral TabletPSN875f3f5a-ed45-4646-8537-21f054302d6f4
977880amiloride hydrochloride 5 MG Oral TabletSCD875f3f5a-ed45-4646-8537-21f054302d6f4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
49884-117-0149884011701100 TABLET in 1 BOTTLE (49884-117-01) 100 tablet1986-05-120000-00-00NoNoCurrent
49884-117-10498840117101000 TABLET in 1 BOTTLE (49884-117-10) 1000 tablet1986-05-120000-00-00NoNoCurrent