Matrix Biolage ScalpSync Antidandruff

Product NDC: 49967-052
11-digit product format: 499670052
Labeler code: 49967
Product ID: 49967-052_cc1a1f6c-ceaa-471f-953d-aa2e5dec3312
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: SHAMPOO
Route: TOPICAL
Labeler: L'Oreal USA Products Inc
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2014-05-01
Substance: PYRITHIONE ZINC
Active strength: 10 mg/mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Matrix Biolage ScalpSync Antidandruff
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8564f2cf-b680-4e2c-8451-f345c9852c1a	Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
49967-052-01	Matrix Biolage ScalpSync Antidandruff	400 mL in 1 BOTTLE	SHAMPOO	400	7
49967-052-02	Matrix Biolage ScalpSync Antidandruff	1000 mL in 1 BOTTLE	SHAMPOO	1000	7
49967-052-03	Matrix Biolage ScalpSync Antidandruff	50 mL in 1 BOTTLE	SHAMPOO	50	7

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version	Uploaded
PYRITHIONE ZINC	ACTIVE INGREDIENT	R953O2RHZ5	MATRIX BIOLAGE SCALPSYNC ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [L'OREAL USA PRODUCTS INC]	2
PYRITHIONE ZINC	ACTIVE MOIETY	R953O2RHZ5	MATRIX BIOLAGE SCALPSYNC ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [L'OREAL USA PRODUCTS INC]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
49967-052	MATRIX BIOLAGE SCALPSYNC ANTIDANDRUFF (PYRITHIONE ZINC) SHAMPOO [L'OREAL USA PRODUCTS INC]	7	Current NDC, Legacy NDC, 3 package rows	20240719_8564f2cf-b680-4e2c-8451-f345c9852c1a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 12 of 31 · 615 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Anti-Fungal	ANTI-FUNGAL SHAMPOO	Shenzhen Mengyue Technology Co., Ltd.	482c0243-1073-f578-e063-6294a90adf5c	2026-01-15	Warnings	Exact identifier application number: M032
Kenkoderm Psoriasis Moisturizing	SALICYLIC ACID	Olympus Trading Company, LLC	ca9e4168-dfe9-4fb0-b78d-83b9fe5205f8	2026-01-09	Warnings	Exact identifier application number: M032
Kenkoderm Psoriasis	SALICYLIC ACID	Olympus Trading Company, LLC	9143edff-9809-4620-96fe-6293d5b75df8	2026-01-09	Warnings	Exact identifier application number: M032
DZUL ANTI-DANDRUFF CONDITIONER	PYRITHIONE ZINC	Caball Sales, Inc.	05f29038-f14f-4285-e063-6294a90ac980	2026-01-08	Warnings	Exact identifier application number: M032
DZUL ANTI-DANDRUFF	ZINC PYRITHIONE	Caball Sales, Inc.	05e3fac4-c0ce-cbb9-e063-6294a90ac036	2026-01-08	Warnings	Exact identifier application number: M032
Mens Rogaine 2% Salicylic Acid Anti-Dandruff Plus Conditioner	SALICYLIC ACID	Kenvue Brands LLC	44906677-88a2-7c68-e063-6294a90a3017	2026-01-02	Warnings	Exact identifier application number: M032
Max OUT	BENZALKONIUM CHLORIDE	Unico	475903d2-a0b0-5d29-e063-6394a90a528f	2026-01-01	Warnings	Exact identifier application number: M032
Flakes Cedar Mint Anti Dandruff	PYRITHIONE ZINC	Cosco International, Inc.	8575e7a0-4290-40a0-949c-317951b440b8	2026-01-01	Warnings	Exact identifier application number: M032
Head and Shoulders Clinical Strength Dandruff Defense Intensive Itch Relief	SELENIUM SULFIDE	The Procter & Gamble Manufacturing Company	b6ad7707-9d02-31a6-e053-2a95a90ae7ad	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders 2in1 Clinical Strength Dandruff Defense Intensive Itch Relief	SELENIUM SULFIDE	The Procter & Gamble Manufacturing Company	b6ada541-f12b-76f2-e053-2a95a90a5286	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Lemon Oil 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	e7903f3d-9c5a-f397-e053-2995a90a7895	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders 2in1 Dry Scalp Care with Almond and Coconut Oil	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	ed0bd699-c243-60f4-e053-2995a90a781f	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Shea Butter	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f80a1580-38ba-3dae-e053-6394a90aff5d	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Ginger 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f80a83cc-1174-3ec3-e053-6394a90ab012	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Shea Butter Hair and Scalp Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f7ff4442-5d3f-034a-e053-6394a90a686d	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Clinical Dry Scalp Rescue Kit	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	1a3ac96a-04ec-6865-e063-6394a90a9fb8	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Deep Scalp Hydration Daily	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f80aee91-5643-ebbc-e053-6294a90aa5ab	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Deep Scalp Cleanse Daily	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f81e8a83-db95-8246-e053-6294a90a40a4	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Deep Scalp Cleanse 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f81eb5d0-e392-0152-e053-6294a90a2907	2025-12-31	Warnings	Exact identifier application number: M032
Head and Shoulders Deep Scalp Hydration 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	f80e8a60-2b0f-dce2-e053-6394a90ab275	2025-12-31	Warnings	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	8564f2cf-b680-4e2c-8451-f345c9852c1a	7
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	8564f2cf-b680-4e2c-8451-f345c9852c1a	7
209884	zinc pyrithione 1 % Medicated Conditioner	SY	8564f2cf-b680-4e2c-8451-f345c9852c1a	7
209884	zinc pyrithione 1 % Medicated Shampoo	SY	8564f2cf-b680-4e2c-8451-f345c9852c1a	7

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
49967-052-01	49967005201	400 mL in 1 BOTTLE (49967-052-01)	400 ml	2014-05-01	0000-00-00	No	No	Current
49967-052-02	49967005202	1000 mL in 1 BOTTLE (49967-052-02)	1000 ml	2014-05-01	0000-00-00	No	No	Current
49967-052-03	49967005203	50 mL in 1 BOTTLE (49967-052-03)	50 ml	2024-02-01		No	No	Current