LETROZOLE

Product NDC
50268-476
11-digit product format
502680476
Labeler code
50268
Product ID
50268-476_48d4cf4a-83a7-4e5f-e063-6394a90a4ece
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
LETROZOLE
Dosage form
TABLET
Route
ORAL
Labeler
AvPAK
Application
ANDA200161
Marketing category
ANDA
Marketing start
2019-10-02
Substance
LETROZOLE
Active strength
2.5 mg/1
Pharmacologic classes
Aromatase Inhibitor [EPC], Aromatase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A200161-001LETROZOLELETROZOLE2.5MGTABLET / ORALAB2011-06-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A200161-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-0387673890dc5c…
2021-03-12 10:30 UTC2021-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-035aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-038869cabd3fbd…
2020-11-12 02:37 UTC2020-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03c0c555d07b60…
2019-12-14 00:12 UTC2019-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033f01610625f2…
2019-09-15 20:21 UTC2019-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03b00525d2431f…
2019-07-19 19:46 UTC2019-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-036a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-031c564ffb4f44…
2023-12-20 04:57 UTC2023-12A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-039b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033f0d92c62455…
2023-05-13 08:27 UTC2023-05A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03053a50430f4f…
2023-01-26 05:58 UTC2023-01A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-033a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A200161-001LETROZOLE2.5MGTABLET / ORALAB2011-06-03e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A200161-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A200161-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200161-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A200161-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200161-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200161-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200161-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200161-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200161-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200161-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200161-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200161-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200161-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200161-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200161-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200161-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200161-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200161-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200161-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200161-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200161-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A200161-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A200161-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A200161-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A200161-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A200161-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A200161-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A200161-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A200161-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A200161-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A200161-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A200161-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A200161-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A200161-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A200161-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A200161-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A200161-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A200161-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A200161-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A200161-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
LETROZOLE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LETROZOLE2.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7LKK855W8IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
200064Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
93f317f1-96d1-498e-e053-2995a90ac60dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d50ad188-a2a9-1aec-5d6c-f8612e9e5867Product name420190528
4f1e9b6f-5fe1-47c9-ab31-3c39ee923083Product name220170713

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50268-476-11LETROZOLE1 in 1 BLISTER PACKTABLET15
50268-476-15LETROZOLE50 in 1 BOXTABLET505

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50268-476-11EA - Each50268-476ea96e760-0007-4407-adc2-d155e9dda7e812019-11-12
50268-476-15EA - Each50268-4763722763c-54ff-4338-9b55-6d9098fe2b0112019-11-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50268-476LETROZOLE TABLET [AVPAK]3Current NDC, Legacy NDC, 2 package rows20240110_93f317f1-96d1-498e-e053-2995a90ac60d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LETROZOLELETROZOLEBreckenridge Pharmaceutical, Inc.63e54b62-a30d-4a56-9215-75e7a0b0bf022026-07-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LETROZOLELETROZOLEA-S Medication Solutions3baa3912-3e64-473b-8ec6-8557aa7907c22026-06-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LETROZOLELETROZOLEAvPAK93f317f1-96d1-498e-e053-2995a90ac60d2026-01-20Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
ndc (product): 50268-476
LETROZOLELETROZOLEBryant Ranch Prepack3cc750a5-cc88-4b42-b4ab-a87e760f291d2024-05-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161
LetrozoleLETROZOLENatco Pharma Limited35c73219-c39e-4e10-b944-76009b061e792020-11-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200161
application number: ANDA200161

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
200064letrozole 2.5 MG Oral TabletPSN93f317f1-96d1-498e-e053-2995a90ac60d5
200064letrozole 2.5 MG Oral TabletSCD93f317f1-96d1-498e-e053-2995a90ac60d5

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50268-476-11502680476111 in 1 BLISTER PACKHistorical
50268-476-155026804761550 BLISTER PACK in 1 BOX (50268-476-15) / 1 TABLET in 1 BLISTER PACK (50268-476-11) 50 blister pack2019-10-020000-00-00NoNoCurrent