Rheumatoid Arthritis Pain Management

Product NDC: 51393-7522
11-digit product format: 513937522
Labeler code: 51393
Product ID: 51393-7522_dc6563c3-3f18-4d5a-bf44-02304df92733
Type: HUMAN OTC DRUG
Nonproprietary name: Horse Chestnut, Caulophyllum Thalictroides Root, Phytolacca Americana Root, Ruta Graveolens Flowering Top, and Silicon Dioxide
Dosage form: SOLUTION/ DROPS
Route: TOPICAL
Labeler: Forces of Nature
Marketing category: UNAPPROVED HOMEOPATHIC
Marketing start: 2013-01-01
Marketing end: 0000-00-00
Substance: HORSE CHESTNUT; CAULOPHYLLUM THALICTROIDES ROOT; PHYTOLACCA AMERICANA ROOT; RUTA GRAVEOLENS FLOWERING TOP; SILICON DIOXIDE
Active strength: 12 [hp_C]/100mL; [hp_X]/100mL; [hp_C]/100mL; [hp_C]/100mL; [hp_X]/100mL
NDC exclude flag: No
Listing certified through: 2019-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	51393-7522		I	Inactivated by FDA	2026-10-05
excluded package	package	51393-7522	51393-7522-1	I	Inactivated by FDA	2026-10-05
excluded package	package	51393-7522	51393-7522-2	I	Inactivated by FDA	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 2 · 63 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	51393-7522-2	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	51393-7522-1	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	51393-7522-2	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	51393-7522-1	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	51393-7522-2	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	51393-7522-1	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	51393-7522-2	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	51393-7522-1	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	51393-7522-2	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	51393-7522-1	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	51393-7522-2	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	51393-7522-1	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	51393-7522-2	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	51393-7522-1	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	51393-7522-2	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	51393-7522-1	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	51393-7522-2	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	51393-7522-1	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	51393-7522-2	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	51393-7522-1	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	51393-7522-2	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	51393-7522-1	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	51393-7522-2	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	51393-7522-1	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	51393-7522-2	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	51393-7522-1	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	51393-7522-2	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	51393-7522-1	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	51393-7522-2	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	51393-7522-1	`1332a3947898…`	`d4bfe170f9cd…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded product	product		`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	51393-7522-2	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-08-30 03:57 UTC · source 2022-08-29	excluded package	package	51393-7522-1	`fb8cb913e6d1…`	`eb8c232b6be0…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded product	product		`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	51393-7522-2	`86f5da6cb304…`	`a595104c45d7…`
2022-04-09 23:13 UTC · source 2022-04-08	excluded package	package	51393-7522-1	`86f5da6cb304…`	`a595104c45d7…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded product	product		`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	51393-7522-2	`bd6a592717d7…`	`303034d00443…`
2022-04-04 05:40 UTC · source 2022-04-01	excluded package	package	51393-7522-1	`bd6a592717d7…`	`303034d00443…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded product	product		`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	51393-7522-2	`8dfbde2a14a4…`	`c9ff85d89658…`
2021-12-27 23:28 UTC · source 2021-12-27	excluded package	package	51393-7522-1	`8dfbde2a14a4…`	`c9ff85d89658…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded product	product		`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	51393-7522-2	`e2bbac7714bc…`	`27bdfed8d636…`
2020-12-18 03:04 UTC · source 2020-12-17	excluded package	package	51393-7522-1	`e2bbac7714bc…`	`27bdfed8d636…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
51393-7522-1	2020-01-31	C162847	48780-1	9d75b9d1-07da-f424-e053-dadaa90a57ce	Rheumatoid Arthritis Pain Management
51393-7522-2	2020-01-31	C162847	48780-1	9d75b9d1-07da-f424-e053-dadaa90a57ce	Rheumatoid Arthritis Pain Management

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
51393-7522-1	Rheumatoid Arthritis Pain Management	1 in 1 BOX	SOLUTION/ DROPS	1	1
51393-7522-1	Rheumatoid Arthritis Pain Management	11 mL in 1 BOTTLE, DISPENSING	SOLUTION/ DROPS	11	1
51393-7522-2	Rheumatoid Arthritis Pain Management	33 mL in 1 BOTTLE, DISPENSING	SOLUTION/ DROPS	33	1
51393-7522-2	Rheumatoid Arthritis Pain Management	1 in 1 BOX	SOLUTION/ DROPS	1	1

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Caulophyllum Thalictroides Root	ACTIVE INGREDIENT	JTJ6HH6YEH	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Horse Chestnut	ACTIVE INGREDIENT	3C18L6RJAZ	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Phytolacca Americana Root	ACTIVE INGREDIENT	11E6VI8VEG	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Ruta Graveolens Flowering Top	ACTIVE INGREDIENT	N94C2U587S	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Silicon Dioxide	ACTIVE INGREDIENT	ETJ7Z6XBU4	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Caulophyllum Thalictroides Root	ACTIVE MOIETY	JTJ6HH6YEH	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Horse Chestnut	ACTIVE MOIETY	3C18L6RJAZ	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Phytolacca Americana Root	ACTIVE MOIETY	11E6VI8VEG	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Ruta Graveolens Flowering Top	ACTIVE MOIETY	N94C2U587S	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Silicon Dioxide	ACTIVE MOIETY	ETJ7Z6XBU4	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Cupressus Sempervirens Whole	INACTIVE INGREDIENT	V0IW9P606J	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Eucalyptus Radiata Leaf Oil	INACTIVE INGREDIENT	SB9A7612BD	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Ginger	INACTIVE INGREDIENT	C5529G5JPQ	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Lavandin Oil	INACTIVE INGREDIENT	9RES347CKG	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Matricaria Chamomilla Flowering Top Oil	INACTIVE INGREDIENT	SA8AR2W4ER	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Picea Mariana Leaf Oil	INACTIVE INGREDIENT	Q1J49L1A5O	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Pine Needle Oil (PINUS SYLVESTRIS)	INACTIVE INGREDIENT	5EXL5H740Y	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1
Sesame Oil	INACTIVE INGREDIENT	QX10HYY4QV	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
51393-7522	RHEUMATOID ARTHRITIS PAIN MANAGEMENT (HORSE CHESTNUT, CAULOPHYLLUM THALICTROIDES ROOT, PHYTOLACCA AMERICANA ROOT, RUTA GRAVEOLENS FLOWERING TOP, AND SILICON DIOXIDE) SOLUTION/ DROPS [FORCES OF NATURE]	1	Legacy NDC, 4 package rows	20131204_21935138-dee4-443b-a691-f4d3708a80c0.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
3C18L6RJAZ	HORSE CHESTNUT		HORSE CHESTNUT
JTJ6HH6YEH	CAULOPHYLLUM THALICTROIDES ROOT		CAULOPHYLLUM THALICTROIDES ROOT
11E6VI8VEG	PHYTOLACCA AMERICANA ROOT		PHYTOLACCA AMERICANA ROOT
N94C2U587S	RUTA GRAVEOLENS FLOWERING TOP		RUTA GRAVEOLENS FLOWERING TOP
ETJ7Z6XBU4	SILICON DIOXIDE	7631-86-9	SILICON DIOXIDE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
51393-7522-1	51393752201	1 in 1 BOX		Historical
51393-7522-2	51393752202	33 mL in 1 BOTTLE, DISPENSING	33 ml	Historical