Cystadane

Product NDC
52276-400
11-digit product format
522760400
Labeler code
52276
Product ID
52276-400_3a4fdd66-b72b-4aa3-94bb-bac8af98b150
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
betaine
Dosage form
POWDER, FOR SOLUTION
Route
ORAL
Labeler
Recordati Rare Diseases
Application
NDA020576
Marketing category
NDA
Marketing start
1996-10-25
Substance
BETAINE
Active strength
1 g/g
Pharmacologic classes
Methylating Activity [MoA], Methylating Agent [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020576-001CYSTADANEBETAINE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N020576-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-2587673890dc5c…
2021-03-12 10:30 UTC2021-03N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-253f01610625f2…
2019-09-15 20:21 UTC2019-09N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-25b00525d2431f…
2019-07-19 19:46 UTC2019-07N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALRLD, RS1996-10-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-253f0d92c62455…
2023-05-13 08:27 UTC2023-05N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25053a50430f4f…
2023-01-26 05:58 UTC2023-01N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N020576-001CYSTADANE1GM/SCOOPFULFOR SOLUTION / ORALABRLD, RS1996-10-25cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N020576-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020576-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020576-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020576-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020576-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020576-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020576-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020576-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020576-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020576-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020576-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020576-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020576-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020576-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020576-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020576-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020576-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N020576-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020576-001AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020576-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020576-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020576-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020576-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020576-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020576-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020576-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N020576-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N020576-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020576-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020576-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020576-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N020576-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N020576-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Cystadane
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BETAINE1 g/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3SCV180C9WInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
404539Internal RxNorm lookup
562847Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
31a684d0-cd98-4e46-b43a-ccbd17c41559Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d1c9d1af-bddd-448d-86f7-69052b7d5b47Product name120220627

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
52276-400-01Cystadane180 g in 1 BOTTLEPOWDER, FOR SOLUTION1807

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
52276-400-01GM - Gram52276-40062ac2aa5-176d-41ae-811c-608ac799f54b12017-05-03

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
52276-400CYSTADANE (BETAINE) POWDER, FOR SOLUTION [RECORDATI RARE DISEASES]5Current NDC, Legacy NDC, 1 package rows20230112_31a684d0-cd98-4e46-b43a-ccbd17c41559.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CystadaneBETAINERecordati Rare Diseases31a684d0-cd98-4e46-b43a-ccbd17c415592026-04-24Warnings, Adverse reactionsExact identifier
application applno (NDA): 020576
application number: NDA020576
ndc (product): 52276-400

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
562847betaine anhydrous 1 GM/Scoop Powder for Oral SolutionPSN31a684d0-cd98-4e46-b43a-ccbd17c415597
404539Cystadane 1 GM/Scoop Powder for Oral SolutionPSN31a684d0-cd98-4e46-b43a-ccbd17c415597
404539betaine 1000 MG Powder for Oral Solution [Cystadane]SBD31a684d0-cd98-4e46-b43a-ccbd17c415597
562847betaine 1000 MG Powder for Oral SolutionSCD31a684d0-cd98-4e46-b43a-ccbd17c415597
562847betaine anhydrous 1 GM/Scoop Powder for Oral SolutionSY31a684d0-cd98-4e46-b43a-ccbd17c415597
404539Cystadane 1000 MG (as betaine anhydrous) Powder for Oral SolutionSY31a684d0-cd98-4e46-b43a-ccbd17c415597
404539Cystadane 1000 MG Powder for Oral SolutionSY31a684d0-cd98-4e46-b43a-ccbd17c415597

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
52276-400-0152276040001180 g in 1 BOTTLE (52276-400-01) 180 g2017-04-130000-00-00NoNoCurrent