Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)

Product NDC
52579-1604
11-digit product format
525791604
Labeler code
52579
Product ID
52579-1604_7910c69c-9663-69bd-e053-2991aa0aedb4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
tilmanocept
Dosage form
KIT
Labeler
Navidea Biopharmaceuticals, Inc.
Application
NDA202207
Marketing category
NDA
Marketing start
2016-10-20
Marketing end
2019-06-01
Active strength
0
NDC exclude flag
No
Listing certified through
0000-00-00
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct52579-1604DDiscontinued by firm2026-08-03
excluded packagepackage52579-160452579-1604-5DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage52579-1604-5d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage52579-1604-5f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage52579-1604-52ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage52579-1604-5a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage52579-1604-5cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage52579-1604-5cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage52579-1604-5302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage52579-1604-5ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage52579-1604-50efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage52579-1604-5ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage52579-1604-5367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage52579-1604-5557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N202207-001LYMPHOSEEK KITTECHNETIUM TC-99M TILMANOCEPTN/AINJECTABLE / INJECTIONRLD, RS2013-03-13

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N202207-00194399852029-01-30Drug product2016-10-14

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133f01610625f2…
2019-09-15 20:21 UTC2019-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N202207-001LYMPHOSEEK KITN/AINJECTABLE / INJECTIONRLD, RS2013-03-13cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N202207-00194399852029-01-30Drug product2016-10-14011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-00164099902025-05-12Drug substance31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202207-00194399852029-01-30Drug product2016-10-1431067a03dcf5…
2025-08-23 18:47 UTC2025-08N202207-00164099902025-05-12Drug substance6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202207-00194399852029-01-30Drug product2016-10-146a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-00164099902025-05-12Drug substancefd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202207-00194399852029-01-30Drug product2016-10-14fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-00164099902025-05-12Drug substanceb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202207-00194399852029-01-30Drug product2016-10-14b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-00164099902025-05-12Drug substance03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-00194399852029-01-30Drug product2016-10-1403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-00164099902025-05-12Drug substance2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-00194399852029-01-30Drug product2016-10-142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-00164099902025-05-12Drug substance5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-00194399852029-01-30Drug product2016-10-145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-00164099902025-05-12Drug substanced8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-00194399852029-01-30Drug product2016-10-14d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-00164099902025-05-12Drug substanced06236e962d9…
2024-10-29 15:01 UTC2024-10N202207-00194399852029-01-30Drug product2016-10-14d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-00164099902025-05-12Drug substance79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-00194399852029-01-30Drug product2016-10-1479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-00164099902025-05-12Drug substance301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-00194399852029-01-30Drug product2016-10-14301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-00164099902025-05-12Drug substance1e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-00194399852029-01-30Drug product2016-10-141e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-00164099902025-05-12Drug substance8072bd15b7f6…
2024-05-31 18:47 UTC2024-05N202207-00194399852029-01-30Drug product2016-10-148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-00164099902025-05-12Drug substance5c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-00194399852033-09-27Drug substance, Drug product2016-10-145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-00164099902025-05-12Drug substance5d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N202207-00194399852033-09-27Drug substance, Drug product2016-10-145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-00164099902025-05-12Drug substance4b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N202207-00194399852033-09-27Drug substance, Drug product2016-10-144b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-00164099902020-05-12Drug substance74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N202207-00194399852033-09-27Drug substance, Drug product2016-10-1474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-00164099902025-05-12Drug substancebb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N202207-00194399852033-09-27Drug substance, Drug product2016-10-14bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-00164099902025-05-12Drug substance782e0a99824c…
2021-12-28 21:50 UTC2021-12N202207-00194399852033-09-27Drug substance, Drug product2016-10-14782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-00164099902025-05-12Drug substance87673890dc5c…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202207-001NPP2024-05-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202207-001NPP2024-05-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202207-001NPP2024-05-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202207-001NPP2024-05-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N202207-001NPP2024-05-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N202207-001NPP2024-05-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N202207-001NPP2024-05-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N202207-001NPP2024-05-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05N202207-001NPP2024-05-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N202207-001NPP2024-05-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N202207-001NPP2024-05-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N202207-001NPP2024-05-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N202207-001ODE-672021-06-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N202207-001NPP2024-05-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N202207-001ODE-672021-06-13782e0a99824c…
2021-12-28 21:50 UTC2021-12N202207-001NPP2024-05-19782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N202207-001ODE-672021-06-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N202207-001ODE-672021-06-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N202207-001ODE-672021-06-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N202207-001ODE-672021-06-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N202207-001ODE-672021-06-133f01610625f2…
2019-09-15 20:21 UTC2019-09N202207-001ODE-672021-06-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N202207-001ODE-672021-06-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N202207-001NPP2024-05-196a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N202207-001NPP2024-05-191c564ffb4f44…
2023-12-20 04:57 UTC2023-12N202207-001NPP2024-05-19ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N202207-001NPP2024-05-19a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N202207-001NPP2024-05-199b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N202207-001NPP2024-05-19a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N202207-001NPP2024-05-193f0d92c62455…
2023-05-13 08:27 UTC2023-05N202207-001NPP2024-05-19053a50430f4f…
2023-01-26 05:58 UTC2023-01N202207-001NPP2024-05-193bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N202207-001NPP2024-05-193a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N202207-001NPP2024-05-19f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N202207-001NPP2024-05-19e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N202207-001NPP2024-05-19cb3db0bc1861…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept)TILMANOCEPTCardinal Health 414, LLC72f31b09-4d7b-475c-b37a-9daf2ad802402025-09-08Warnings, Adverse reactionsExact identifier
application applno (NDA): 202207
application number: NDA202207