Home NDC 58411-237 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER n
Product NDC 58411-237
11-digit product format 584110237
Labeler code 58411
Product ID 58411-237_7df47be5-ab9d-5b67-e053-2a91aa0a6956
Type HUMAN OTC DRUG
Nonproprietary name AVOBENZONE, OCTINOXATE, and OCTOCRYLENE
Dosage form CREAM
Route TOPICAL
Labeler SHISEIDO AMERICAS CORPORATION
Application part352
Marketing category OTC MONOGRAPH NOT FINAL
Marketing start 2014-10-01
Marketing end 0000-00-00
Substance AVOBENZONE; OCTINOXATE; OCTOCRYLENE
Active strength 518 mg/20mL; mg/20mL; mg/20mL
NDC exclude flag No
Listing certified through 2020-12-31
Current FDA listing Historical FDA.report record Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 18 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Dataset, Scope table Captured / source date Dataset Scope Package NDC Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 excluded product product d630ba8d3edf…732f749b63fb…2025-12-14 17:58 UTC · source 2025-12-05 excluded package package 58411-237-10 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 excluded product product f5e01cc5f278…a2eaf40c39c3…2025-08-27 00:01 UTC · source 2025-08-26 excluded package package 58411-237-10 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 excluded product product 2ef7874e63bc…57b86245f4fa…2025-04-01 02:39 UTC · source 2025-03-31 excluded package package 58411-237-10 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 excluded product product a1b67e2a42f9…c4cf2c586c0d…2025-03-28 20:22 UTC · source 2025-03-28 excluded package package 58411-237-10 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 excluded product product cfe11265f3b6…090c488252e2…2025-03-22 03:12 UTC · source 2025-03-21 excluded package package 58411-237-10 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 excluded product product cdf11ea48f46…ba0047e9e063…2025-03-10 12:48 UTC · source 2025-03-10 excluded package package 58411-237-10 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 excluded product product 302b2466d912…e7b80fea0513…2025-02-02 03:52 UTC · source 2025-01-31 excluded package package 58411-237-10 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 excluded product product ed331223b511…672a5bd82f5f…2025-01-20 13:05 UTC · source 2025-01-20 excluded package package 58411-237-10 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 excluded product product 0efc9e666f02…f202fb6c5f17…2025-01-11 03:41 UTC · source 2025-01-10 excluded package package 58411-237-10 0efc9e666f02…f202fb6c5f17…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded AVOBENZONE ACTIVE INGREDIENT G63QQF2NOX CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 OCTINOXATE ACTIVE INGREDIENT 4Y5P7MUD51 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 OCTOCRYLENE ACTIVE INGREDIENT 5A68WGF6WM CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 AVOBENZONE ACTIVE MOIETY G63QQF2NOX CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 OCTINOXATE ACTIVE MOIETY 4Y5P7MUD51 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 OCTOCRYLENE ACTIVE MOIETY 5A68WGF6WM CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 .ALPHA.-TOCOPHEROL INACTIVE INGREDIENT H4N855PNZ1 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 .ALPHA.-TOCOPHEROL ACETATE, DL- INACTIVE INGREDIENT WR1WPI7EW8 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 ALCOHOL INACTIVE INGREDIENT 3K9958V90M CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 BEHENETH-20 INACTIVE INGREDIENT BJ4GP2IFLN CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 BUPLEURUM FALCATUM ROOT INACTIVE INGREDIENT X04E310LUY CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 BUTYLATED HYDROXYTOLUENE INACTIVE INGREDIENT 1P9D0Z171K CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 BUTYLENE GLYCOL INACTIVE INGREDIENT 3XUS85K0RA CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 CARBOXYMETHYLCELLULOSE SODIUM INACTIVE INGREDIENT K679OBS311 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 CHINESE CINNAMON INACTIVE INGREDIENT WS4CQ062KM CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 CITRIC ACID MONOHYDRATE INACTIVE INGREDIENT 2968PHW8QP CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 DIGLYCINE INACTIVE INGREDIENT 10525P22U0 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 DIMETHICONE INACTIVE INGREDIENT 92RU3N3Y1O CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 DIPHENYLSILOXY PHENYL TRIMETHICONE INACTIVE INGREDIENT I445L28B12 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 DIPROPYLENE GLYCOL INACTIVE INGREDIENT E107L85C40 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 DOCOSANOL INACTIVE INGREDIENT 9G1OE216XY CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 EDETATE DISODIUM INACTIVE INGREDIENT 7FLD91C86K CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 FERRIC OXIDE RED INACTIVE INGREDIENT 1K09F3G675 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 FERRIC OXIDE YELLOW INACTIVE INGREDIENT EX438O2MRT CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 GINKGO INACTIVE INGREDIENT 19FUJ2C58T CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 GLYCERIN INACTIVE INGREDIENT PDC6A3C0OX CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 GREEN TEA LEAF INACTIVE INGREDIENT W2ZU1RY8B0 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 HYALURONATE SODIUM INACTIVE INGREDIENT YSE9PPT4TH CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 HYDROGENATED PALM OIL INACTIVE INGREDIENT 257THB963H CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 HYDROGENATED POLYDECENE (550 MW) INACTIVE INGREDIENT U333RI6EB7 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 ISODODECANE INACTIVE INGREDIENT A8289P68Y2 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 ISOSTEARIC ACID INACTIVE INGREDIENT X33R8U0062 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 LAURYL BETAINE INACTIVE INGREDIENT Y4P927Q133 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 METHYL AMINOMETHYLCYCLOHEXANE CARBOXAMIDE HYDROCHLORIDE INACTIVE INGREDIENT ZV6O50F5CP CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 NUPHAR JAPONICA ROOT INACTIVE INGREDIENT 3OPM78C6RQ CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PALM KERNEL OIL INACTIVE INGREDIENT B0S90M0233 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PALM OIL INACTIVE INGREDIENT 5QUO05548Z CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PEG-10 DIMETHICONE (600 CST) INACTIVE INGREDIENT 8PR7V1SVM0 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PEG/PPG-14/7 DIMETHYL ETHER INACTIVE INGREDIENT 6DNW9T7YT2 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PHENOXYETHANOL INACTIVE INGREDIENT HIE492ZZ3T CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 POTASSIUM HYDROXIDE INACTIVE INGREDIENT WZH3C48M4T CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 PPG-17 INACTIVE INGREDIENT OV0Q322E0U CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 SILICON DIOXIDE INACTIVE INGREDIENT ETJ7Z6XBU4 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 SODIUM ACETYLATED HYALURONATE INACTIVE INGREDIENT WN66R7GL93 CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 SODIUM BENZOATE INACTIVE INGREDIENT OJ245FE5EU CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 SODIUM POLYMETAPHOSPHATE INACTIVE INGREDIENT P1BM4ZH95L CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 STEARYL ALCOHOL INACTIVE INGREDIENT 2KR89I4H1Y CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 TRIETHYLHEXANOIN INACTIVE INGREDIENT 7K3W1BIU6K CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 WATER INACTIVE INGREDIENT 059QF0KO0R CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 XANTHAN GUM INACTIVE INGREDIENT TTV12P4NEE CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1 XYLITOL INACTIVE INGREDIENT VCQ006KQ1E CLE DE PEAU BEAUTE SYNACTIF DAYTIME MOISTURIZER N (AVOBENZONE, OCTINOXATE, AND OCTOCRYLENE) CREAM [SHISEIDO AMERICAS CORPORATION] 1
Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 58411-237-10 58411023710 1 BOTTLE in 1 CARTON (58411-237-10) > 20 mL in 1 BOTTLE 1 bottle 2014-10-01 0000-00-00 No No Current