GenRx Daily Defense Skin Repairing

Product NDC: 59088-829
11-digit product format: 590880829
Labeler code: 59088
Product ID: 59088-829_249cafe1-c95b-0070-e063-6394a90a6ba2
Type: HUMAN OTC DRUG
Nonproprietary name: Dimethicone
Dosage form: CREAM
Route: TOPICAL
Labeler: PureTek Corporation
Application: M016
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2013-01-08
Substance: DIMETHICONE
Active strength: 17.5 mg/mL
Pharmacologic classes: Skin Barrier Activity [PE]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded package	package	59088-829	59088-829-05	D	Discontinued by firm	2026-10-16
excluded package	package	59088-829	59088-829-08	D	Discontinued by firm	2026-10-16
excluded package	package	59088-829	59088-829-69	D	Discontinued by firm	2026-10-16

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 36 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	59088-829-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	59088-829-69	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	59088-829-08	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	59088-829-05	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	59088-829-69	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	59088-829-08	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	59088-829-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	59088-829-69	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	59088-829-08	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	59088-829-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	59088-829-69	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	59088-829-08	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	59088-829-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	59088-829-69	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	59088-829-08	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	59088-829-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	59088-829-69	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	59088-829-08	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	59088-829-05	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	59088-829-69	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	59088-829-08	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	59088-829-05	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	59088-829-69	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	59088-829-08	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	59088-829-05	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	59088-829-69	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	59088-829-08	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	59088-829-05	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	59088-829-69	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	59088-829-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	59088-829-05	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	59088-829-69	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	59088-829-08	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	59088-829-05	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	59088-829-69	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	59088-829-08	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: GenRx Daily Defense Skin Repairing
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIMETHICONE	17.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
92RU3N3Y1O	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1148394	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
7d2827fd-b40f-454b-bb60-54d77823b18c	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
59361619-24d9-b610-eca6-5a7f25ed5e03	Product name	5	20240909
5e18e798-5614-cf5c-0185-38b1cb77a093	Product name	2	20160822

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
59088-829-01	GenRx Daily Defense Skin Repairing	4 mL in 1 POUCH	CREAM	4	4
59088-829-05	GenRx Daily Defense Skin Repairing	59 mL in 1 TUBE	CREAM	59	4
59088-829-08	GenRx Daily Defense Skin Repairing	118 mL in 1 TUBE	CREAM	118	4
59088-829-69	GenRx Daily Defense Skin Repairing	144 in 1 CARTON	CREAM	144	4

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Dimethicone	ACTIVE INGREDIENT	92RU3N3Y1O	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
Dimethicone	ACTIVE MOIETY	92RU3N3Y1O	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
.ALPHA.-TOCOPHEROL ACETATE, DL-	INACTIVE INGREDIENT	WR1WPI7EW8	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
ALOE VERA LEAF	INACTIVE INGREDIENT	ZY81Z83H0X	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
BUTYLENE GLYCOL	INACTIVE INGREDIENT	3XUS85K0RA	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
CALCIUM PANTOTHENATE	INACTIVE INGREDIENT	568ET80C3D	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
CARTHAMUS TINCTORIUS SEED OLEOSOMES	INACTIVE INGREDIENT	9S60Q72309	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
CETYL ALCOHOL	INACTIVE INGREDIENT	936JST6JCN	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
DIMETHICONE/DIENE DIMETHICONE CROSSPOLYMER	INACTIVE INGREDIENT	RSA9I561OK	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
GINGER	INACTIVE INGREDIENT	C5529G5JPQ	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
GLYCERYL MONOSTEARATE	INACTIVE INGREDIENT	230OU9XXE4	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
HYALURONATE SODIUM	INACTIVE INGREDIENT	YSE9PPT4TH	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
KUKUI NUT OIL	INACTIVE INGREDIENT	TP11QR7B8R	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
LEVOMENOL	INACTIVE INGREDIENT	24WE03BX2T	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
MALTODEXTRIN	INACTIVE INGREDIENT	7CVR7L4A2D	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
NIACINAMIDE	INACTIVE INGREDIENT	25X51I8RD4	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
PEG-100 STEARATE	INACTIVE INGREDIENT	YD01N1999R	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
PENTAERYTHRITOL TETRAKIS(3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONATE)	INACTIVE INGREDIENT	255PIF62MS	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
PHENOXYETHANOL	INACTIVE INGREDIENT	HIE492ZZ3T	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
PYRIDOXINE HYDROCHLORIDE	INACTIVE INGREDIENT	68Y4CF58BV	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
SAFFLOWER OIL	INACTIVE INGREDIENT	65UEH262IS	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
SODIUM ASCORBYL PHOSPHATE	INACTIVE INGREDIENT	836SJG51DR	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
TROLAMINE	INACTIVE INGREDIENT	9O3K93S3TK	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
59088-829	GENRX DAILY DEFENSE SKIN REPAIRING (DIMETHICONE) CREAM [PURETEK CORPORATION]	4	Current NDC, Legacy NDC, 4 package rows	20241018_7d2827fd-b40f-454b-bb60-54d77823b18c.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 19 of 68 · 1,357 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Calamine	FERRIC OXIDE RED	Perrigo Direct, Inc	256bd1d4-fd50-408f-9aee-84f218bb4971	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Petroleum	WHITE PETROLATUM	Perrigo Direct, Inc	e11470b2-80d6-4008-b87e-eb6aeadfce74	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Clear Anti-Itch	PRAMOXINE HCL, ZINC ACETATE	Perrigo Direct, Inc	cc0378f2-6d5f-47ec-b16a-64668b4c29cc	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Calamine	CALAMINE, PRAMOXIND HCL	Perrigo Direct, Inc	54a20ec9-ab86-4410-af94-e04393e9d4b3	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Vitamin A D	LANOLIN, PETROLATUM	Meijer, Inc.	adc3bb9b-ed8a-4b65-b44c-1d1e978c89ec	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Diaper Rash	ZINC OXIDE	Meijer, Inc.	1b72f927-c2ae-4190-a035-5d7bb9f53c15	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Petroleum Skin Protectant	WHITE PETROLATUM	Meijer, Inc.	af293cc0-ccd5-42a6-861b-c19fa6ffd06a	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Healing for Babies	PETROLATUM	Meijer, Inc.	09878fe0-0890-4af3-a3f6-d2890041e9f8	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Clear Anti-Itch	PRAMOXINE HCL, ZINC ACETATE	Meijer, Inc.	fa8ae34c-7b68-454f-8a3b-0eaa93a34092	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Baby Diaper Rash	ZINC OXIDE	Meijer, Inc.	04bec667-a11e-42d2-a4b3-1416eebf1e8d	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Healing	PETROLATUM	Meijer, Inc.	8cb56ee4-b9d1-4a29-88c7-e6f3ac2112c1	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Calamine	CALAMINE, PRAMOXINE HCL	Meijer, Inc.	6b369ef2-fd54-4931-a9eb-0fb42834c2ef	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Dimethicone	DIMETHICONE	Meijer, Inc.	75b91b97-ea84-4c4d-9e58-5a9ff27a778c	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Colloidal oatmeal	COLLOIDAL OATMEAL	Meijer, Inc.	d36a7479-7b3b-49fe-8144-b5cce0e173fb	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Daily Moisturizing	DAILY MOISTURIZING	Meijer, Inc.	44949b46-70f2-4e52-adba-a8455da614eb	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Witch Hazel	WITCH HAZEL	Meijer, Inc.	13e4aece-5b91-4f89-a912-540bf170a8d1	2026-02-19	Warnings, Adverse reactions	Exact identifier application number: M016
Diaper Rash	ZINC OXIDE	Target Corporation	7fb5f9ca-cd90-4933-9fe8-907ece00458b	2026-02-18	Warnings, Adverse reactions	Exact identifier application number: M016
Calamine	FERRIC OXIDE RED	Target Corporation	d4ee05c8-ae62-45df-8783-1ed57fa030ec	2026-02-18	Warnings, Adverse reactions	Exact identifier application number: M016
Pure petroleum	WHITE PETROLATUM	Target Corporation	5237c7f2-7135-4558-a758-4fc2a232172f	2026-02-18	Warnings, Adverse reactions	Exact identifier application number: M016
Advanced Healing	PETROLATUM	Target Corporation	3e620e4f-9e29-9e39-e063-6394a90adeda	2026-02-18	Warnings, Adverse reactions	Exact identifier application number: M016

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
92RU3N3Y1O	DIMETHICONE	9006-65-9	DIMETHICONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1148394	dimethicone 1.75 % Topical Cream	PSN	7d2827fd-b40f-454b-bb60-54d77823b18c	4
1148394	dimethicone 17.5 MG/ML Topical Cream	SCD	7d2827fd-b40f-454b-bb60-54d77823b18c	4
1148394	dimethicone 1.75 % Topical Cream	SY	7d2827fd-b40f-454b-bb60-54d77823b18c	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Status
59088-829-01	59088082901	4 mL in 1 POUCH	4 ml	Historical
59088-829-05	59088082905	59 mL in 1 TUBE	59 ml	Historical
59088-829-08	59088082908	118 mL in 1 TUBE	118 ml	Historical
59088-829-69	59088082969	144 in 1 CARTON		Historical