GLEOLAN

Product NDC
59137-231
11-digit product format
591370231
Labeler code
59137
Product ID
59137-231_425c0da5-cec7-4a38-88ee-b230c0601f51
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
AMINOLEVULINIC ACID HYDROCHLORIDE
Dosage form
POWDER, FOR SOLUTION
Route
ORAL
Labeler
Medexus Pharma, Inc.
Application
NDA208630
Marketing category
NDA
Marketing start
2018-04-14
Substance
AMINOLEVULINIC ACID HYDROCHLORIDE
Active strength
1500 mg/1
Pharmacologic classes
Fluorescence Contrast Activity [MoA], Optical Imaging Agent [EPC], Porphyrin Precursor [EPC], Porphyrinogens [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct59137-231DDiscontinued by firm2026-08-17
excluded packagepackage59137-23159137-231-01DDiscontinued by firm2026-08-17

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208630-001GLEOLANAMINOLEVULINIC ACID HYDROCHLORIDE1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-0631067a03dcf5…
2025-08-23 18:47 UTC2025-08N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-066a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-0603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-062680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-065bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-0679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-061e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-068072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-065c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-065d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-064b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-0674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-0687673890dc5c…
2021-03-12 10:30 UTC2021-03N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-065aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-063f01610625f2…
2019-09-15 20:21 UTC2019-09N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06b00525d2431f…
2019-07-19 19:46 UTC2019-07N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-066a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-061c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-069b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-063f0d92c62455…
2023-05-13 08:27 UTC2023-05N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06053a50430f4f…
2023-01-26 05:58 UTC2023-01N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-063bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-063a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208630-001GLEOLAN1.5GM/VIALFOR SOLUTION / ORALRLD, RS2017-06-06e64feba35796…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208630-001ODE-1462024-06-0603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208630-001ODE-1462024-06-062680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208630-001ODE-1462024-06-065bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208630-001ODE-1462024-06-06d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208630-001ODE-1462024-06-06d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208630-001ODE-1462024-06-0679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208630-001ODE-1462024-06-06301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208630-001ODE-1462024-06-061e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208630-001ODE-1462024-06-068072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208630-001ODE-1462024-06-065c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208630-001ODE-1462024-06-065d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208630-001ODE-1462024-06-064b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208630-001ODE-1462024-06-0674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208630-001ODE-1462024-06-06bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208630-001ODE-1462024-06-06782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208630-001ODE-1462024-06-0687673890dc5c…
2021-03-12 10:30 UTC2021-03N208630-001ODE-1462024-06-065aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208630-001ODE-1462024-06-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208630-001ODE-1462024-06-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208630-001ODE-1462024-06-063f01610625f2…
2019-09-15 20:21 UTC2019-09N208630-001ODE-1462024-06-06b00525d2431f…
2019-07-19 19:46 UTC2019-07N208630-001ODE-1462024-06-06ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208630-001ODE-1462024-06-066a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208630-001ODE-1462024-06-061c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208630-001ODE-1462024-06-06ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208630-001ODE-1462024-06-06a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208630-001ODE-1462024-06-069b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208630-001ODE-1462024-06-06a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208630-001ODE-1462024-06-063f0d92c62455…
2023-05-13 08:27 UTC2023-05N208630-001ODE-1462024-06-06053a50430f4f…
2023-01-26 05:58 UTC2023-01N208630-001ODE-1462024-06-063bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208630-001ODE-1462024-06-063a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208630-001ODE-1462024-06-06f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208630-001ODE-1462024-06-06e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N208630-001ODE-1462024-06-06cb3db0bc1861…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c09e7fc3-90f5-4f9d-96f4-e1a857de4102Product name120230718
36aa7500-f1f6-4316-9cf2-688d1cdea23aProduct name120190402
15592b85-0e03-4d08-b78d-bef98f30a3f5Product name120180529

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59137-231-01GLEOLAN1 in 1 VIAL, SINGLE-DOSEPOWDER, FOR SOLUTION13
59137-231-01GLEOLAN1 in 1 CARTONPOWDER, FOR SOLUTION13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59137-231-01EA - Each59137-2311389aac0-1c81-4faf-9b14-8d725c2e40df12022-08-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
59137-231GLEOLAN (AMINOLEVULINIC ACID HYDROCHLORIDE) POWDER, FOR SOLUTION [MEDEXUS PHARMA, INC.]3Current NDC, Legacy NDC, 2 package rows20240507_4873911e-a5d7-47e3-9679-fa5c95999323.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
GLEOLANAMINOLEVULINIC ACID HYDROCHLORIDENX DEVELOPMENT CORPcdeded66-0017-42cf-9471-13f2310143232026-01-29Warnings, Adverse reactionsExact identifier
application applno (NDA): 208630
application number: NDA208630

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
59137-231-01591370231011 VIAL, SINGLE-DOSE in 1 CARTON (59137-231-01) / 1 POWDER, FOR SOLUTION in 1 VIAL, SINGLE-DOSE2022-03-010000-00-00NoNoCurrent