ISTODAX

Product NDC
59572-984
11-digit product format
595720984
Labeler code
59572
Product ID
59572-984_08c46856-2700-4885-ba5d-dced9d8056e1
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
romidepsin
Dosage form
KIT
Labeler
Celgene Corporation
Application
NDA022393
Marketing category
NDA
Marketing start
2010-01-04
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022393-001ISTODAXROMIDEPSIN10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N022393-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-0587673890dc5c…
2021-03-12 10:30 UTC2021-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-053f01610625f2…
2019-09-15 20:21 UTC2019-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05b00525d2431f…
2019-07-19 19:46 UTC2019-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053f0d92c62455…
2023-05-13 08:27 UTC2023-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05053a50430f4f…
2023-01-26 05:58 UTC2023-01N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N022393-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022393-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N022393-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022393-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022393-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022393-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022393-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022393-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022393-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022393-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022393-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022393-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022393-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022393-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022393-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022393-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022393-001AP14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N022393-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022393-001AP1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022393-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022393-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022393-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022393-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022393-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022393-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022393-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05N022393-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01N022393-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022393-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022393-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022393-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N022393-001AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N022393-001AP1a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N022393-00176082802021-08-22Drug substance74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N022393-00176117242021-08-22Drug substance74a2ff9319b5…
2021-12-28 21:50 UTC2021-12N022393-00176082802021-08-22Drug substance782e0a99824c…
2021-12-28 21:50 UTC2021-12N022393-00176117242021-08-22Drug substance782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-00176082802021-08-22Drug substance87673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-00176117242021-08-22Drug substance87673890dc5c…
2021-03-12 10:30 UTC2021-03N022393-00176082802021-08-22Drug substance5aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N022393-00176117242021-08-22Drug substance5aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022393-00176082802021-08-22Drug substance8869cabd3fbd…
2020-12-22 03:56 UTC2020-12N022393-00176117242021-08-22Drug substance8869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022393-00176082802021-08-22Drug substancec0c555d07b60…
2020-11-12 02:37 UTC2020-11N022393-00176117242021-08-22Drug substancec0c555d07b60…
2019-12-14 00:12 UTC2019-12N022393-00176082802021-08-22Drug substance3f01610625f2…
2019-12-14 00:12 UTC2019-12N022393-00176117242021-08-22Drug substance3f01610625f2…
2019-09-15 20:21 UTC2019-09N022393-00176082802021-08-22Drug substanceb00525d2431f…
2019-09-15 20:21 UTC2019-09N022393-00176117242021-08-22Drug substanceb00525d2431f…
2019-07-19 19:46 UTC2019-07N022393-00176082802021-08-22Drug substanceea99ee380514…
2019-07-19 19:46 UTC2019-07N022393-00176117242021-08-22Drug substanceea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
ISTODAX
Listing expiration
2026-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
877513Internal RxNorm lookup
877516Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
03b39d40-90fe-11df-9de6-0002a5d5c51bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2c2c8a1a-7539-4509-bd44-fdddec81b4c6Product name120220317
2fea1353-3917-43fe-aae3-e1defd773273Product name120200708
7792dadb-52b6-46b6-8fdf-80b1171065b5Product name120180810

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59572-962-10ISTODAX2.2 mL in 1 VIAL, GLASSINJECTION, POWDER, LYOPHILIZED,2.2 mL10 mg in 2mL21
59572-984-01ISTODAX1 in 1 CARTONKIT121

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59572-984-01EA - Each59572-9846e6ddb31-0baa-46bd-9b4e-bd741ec2385512016-10-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
romidepsinACTIVE INGREDIENTCX3T89XQBKISTODAX (ROMIDEPSIN) KIT [CELGENE CORPORATION]13
romidepsinACTIVE MOIETYCX3T89XQBKISTODAX (ROMIDEPSIN) KIT [CELGENE CORPORATION]13
povidoneINACTIVE INGREDIENTFZ989GH94EISTODAX (ROMIDEPSIN) KIT [CELGENE CORPORATION]13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
59572-984ISTODAX (ROMIDEPSIN) KIT [CELGENE CORPORATION]21Current NDC, Legacy NDC, 2 package rows20230603_03b39d40-90fe-11df-9de6-0002a5d5c51b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ISTODAXROMIDEPSINCelgene Corporation03b39d40-90fe-11df-9de6-0002a5d5c51b2023-01-31Warnings, Adverse reactionsExact identifier
application applno (NDA): 022393
application number: NDA022393
ndc (product): 59572-984

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
877516ISTODAX 10 MG InjectionPSN03b39d40-90fe-11df-9de6-0002a5d5c51b21
877513romiDEPsin 10 MG InjectionPSN03b39d40-90fe-11df-9de6-0002a5d5c51b21
877516romidepsin 10 MG Injection [Istodax]SBD03b39d40-90fe-11df-9de6-0002a5d5c51b21
877513romidepsin 10 MG InjectionSCD03b39d40-90fe-11df-9de6-0002a5d5c51b21
877516Istodax 10 MG InjectionSY03b39d40-90fe-11df-9de6-0002a5d5c51b21

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
59572-962-10595720962102.2 mL in 1 VIAL, GLASS2.2 mlHistorical
59572-984-01595720984011 KIT in 1 CARTON (59572-984-01) * 2.2 mL in 1 VIAL, GLASS (59572-962-10) * 2.4 mL in 1 VIAL, GLASS (59572-973-02) 1 kit2010-01-040000-00-00NoNoCurrent