Spironolactone and Hydrochlorothiazide

Product NDC
59762-5014
11-digit product format
597625014
Labeler code
59762
Product ID
59762-5014_84a7e143-8b37-4adc-a07b-2da581124df5
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
spironolactone and hydrochlorothiazide
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Greenstone LLC
Application
NDA012616
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
1978-01-01
Marketing end
0000-00-00
Substance
HYDROCHLOROTHIAZIDE; SPIRONOLACTONE
Active strength
25 mg/1; mg/1
Pharmacologic classes
Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA], Increased Diuresis [PE], Thiazide Diuretic [EPC], Thiazides [CS]
NDC exclude flag
No
Listing certified through
2024-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct59762-5014DDiscontinued by firm2026-08-17
excluded packagepackage59762-501459762-5014-1DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 4 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage59762-5014-1d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage59762-5014-1f5e01cc5f278…a2eaf40c39c3…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N012616-004ALDACTAZIDEHYDROCHLOROTHIAZIDE; SPIRONOLACTONE25MG;25MGTABLET / ORALABRLD1982-12-30
N012616-005ALDACTAZIDEHYDROCHLOROTHIAZIDE; SPIRONOLACTONE50MG;50MGTABLET / ORALRLD1982-12-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N012616-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30caaa826d4ba7…
2026-08-18 06:07:402026-07N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30d06236e962d9…
2024-10-29 15:01 UTC2024-10N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-3079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-301e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-308072bd15b7f6…
2024-05-31 18:47 UTC2024-05N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD1982-12-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-305c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD, RS1982-12-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-305d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD, RS1982-12-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-304b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD, RS1982-12-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-3074a2ff9319b5…
2019-12-13 00:20 UTC2019-12N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD, RS1982-12-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03N012616-004ALDACTAZIDE25MG;25MGTABLET / ORALABRLD1982-12-30bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N012616-005ALDACTAZIDE50MG;50MGTABLET / ORALRLD, RS1982-12-30bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N012616-004AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N012616-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012616-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N012616-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012616-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012616-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012616-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012616-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012616-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012616-004AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N012616-004AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012616-004AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012616-004AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012616-004AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N012616-004AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012616-004AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N012616-004AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N012616-004AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N012616-004AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N012616-004AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N012616-004AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N012616-004AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N012616-004AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N012616-004AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N012616-004AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N012616-004AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N012616-004AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N012616-004AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N012616-004AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N012616-004AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N012616-004AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N012616-004AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N012616-004AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N012616-004AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N012616-004AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N012616-004AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N012616-004AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N012616-004AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N012616-004AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N012616-004AB1e64feba35796…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59762-5014-1EA - Each59762-5014aa1d8675-ba01-4475-b655-c164ad2005be12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
HYDROCHLOROTHIAZIDEACTIVE INGREDIENT0J48LPH2THSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
SPIRONOLACTONEACTIVE INGREDIENT27O7W4T232SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
HYDROCHLOROTHIAZIDEACTIVE MOIETY0J48LPH2THSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
SPIRONOLACTONEACTIVE MOIETY27O7W4T232SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
CALCIUM SULFATEINACTIVE INGREDIENTWAT0DDB505SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
HYDROXYPROPYL CELLULOSE (TYPE H)INACTIVE INGREDIENTRFW2ET671PSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1ASPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
POVIDONESINACTIVE INGREDIENTFZ989GH94ESPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
STARCH, CORNINACTIVE INGREDIENTO8232NY3SJSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPSPIRONOLACTONE AND HYDROCHLOROTHIAZIDE TABLET, FILM COATED [GREENSTONE LLC]7

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Spironolactone and HydrochlorothiazideSPIRONOLACTONE AND HYDROCHLOROTHIAZIDEPrasco Laboratories9d350fa2-d568-4970-a7a5-d128ff5d0a2f2026-02-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 012616
application number: NDA012616

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
59762-5014-159762501401100 TABLET, FILM COATED in 1 BOTTLE (59762-5014-1) 1978-01-010000-00-00NoNoCurrent