Home NDC 59779-334-07 Headache Relief
Product NDC 59779-334
Requested package NDC 59779-334-07
11-digit product format 597790334
Labeler code 59779
Product ID 59779-334_bb9d51b6-46a6-4239-97db-392a44755857
Type HUMAN OTC DRUG
Nonproprietary name Acetaminophen, Aspirin and Caffeine
Dosage form TABLET, FILM COATED
Route ORAL
Labeler CVS Pharmacy
Application M013
Marketing category OTC MONOGRAPH DRUG
Marketing start 2008-03-13
Substance ACETAMINOPHEN; ASPIRIN; CAFFEINE
Active strength 250; 250; 65 mg/1; mg/1; mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Methylxanthine [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], Xanthines [CS]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 12 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Snapshot, Source SHA-256 table Captured / source date Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 0efc9e666f02…f202fb6c5f17…2024-11-09 02:27 UTC · source 2024-11-08 ad56d346431e…cc804d4bbf1e…2024-10-04 04:10 UTC · source 2024-10-03 367a005e9d99…383a685ebd0f…2024-07-10 04:00 UTC · source 2024-07-09 557ba5c1ecfa…9c80585c8c6e…
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Headache Relief
Brand name suffix Extra Strength
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength ACETAMINOPHEN 250 mg/1 ASPIRIN 250 mg/1 CAFFEINE 65 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 3 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 362O9ITL9D Internal UNII lookup R16CO5Y76E Internal UNII lookup 3G6A5W338E Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 308297 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 59779-334-06 Headache ReliefExtra Strength 200 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 200 41 59779-334-07 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 41 59779-334-07 Headache ReliefExtra Strength 36 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 36 41 59779-334-08 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 41 59779-334-08 Headache ReliefExtra Strength 24 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 24 41 59779-334-12 Headache ReliefExtra Strength 100 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 100 41 59779-334-12 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 41 59779-334-13 Headache ReliefExtra Strength 250 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 250 41 59779-334-13 Headache ReliefExtra Strength 1 in 1 CARTON TABLET, FILM COATED 1 41 59779-334-17 Headache ReliefExtra Strength 300 in 1 BOTTLE, PLASTIC TABLET, FILM COATED 300 41
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded ACETAMINOPHEN ACTIVE INGREDIENT 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 ASPIRIN ACTIVE INGREDIENT R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 CAFFEINE ACTIVE INGREDIENT 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 ACETAMINOPHEN ACTIVE MOIETY 362O9ITL9D HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 ASPIRIN ACTIVE MOIETY R16CO5Y76E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 CAFFEINE ACTIVE MOIETY 3G6A5W338E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 CELLULOSE, MICROCRYSTALLINE INACTIVE INGREDIENT OP1R32D61U HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 HYPROMELLOSES INACTIVE INGREDIENT 3NXW29V3WO HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 POVIDONES INACTIVE INGREDIENT FZ989GH94E HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 SODIUM LAURYL SULFATE INACTIVE INGREDIENT 368GB5141J HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 SODIUM STARCH GLYCOLATE TYPE A POTATO INACTIVE INGREDIENT 5856J3G2A2 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 STEARIC ACID INACTIVE INGREDIENT 4ELV7Z65AP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [WOONSOCKET PRESCRIPTION CENTER,INCORPORATED] 24
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 59779-334 HEADACHE RELIEF EXTRA STRENGTH (ACETAMINOPHEN, ASPIRIN AND CAFFEINE) TABLET, FILM COATED [CVS PHARMACY] 38 Current NDC, Legacy NDC, 10 package rows 20240718_31ccc867-ca83-70a9-f3d5-5644030047b8.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 37 of 79 · 1,570 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Pain Relief PM Extra Strength ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE TopCo Associates LLC 3b672ec7-8658-4b43-a79d-094ac8bc6904 2025-09-29 Warnings Exact identifier application number: M013 kirkland signature acetaminophen adult extra strength ACETAMINOPHEN Costco Wholesale Company a9979167-1a82-47d7-9602-2865f9bdd628 2025-09-27 Warnings Exact identifier application number: M013 First Aid Direct Chewable Aspirin ASPIRIN Cintas Corp ff6960f6-9f55-4f32-9ab5-9187724531e9 2025-09-25 Warnings Exact identifier application number: M013 Bayer Rapid Relief Body Pain ASPIRIN/CAFFEINE ORAL POWDER Bayer HealthCare LLC. 3fa1ec07-d1a6-226b-e063-6394a90a3213 2025-09-25 Warnings Exact identifier application number: M013 Xpect Chewable Aspirin ASPIRIN Cintas Corporation bddce374-1d35-4685-987d-4a4cc9994155 2025-09-25 Warnings Exact identifier application number: M013 IBUPROFEN IBUPROFEN Kroger Company bbedfc37-913d-8046-e053-2995a90af68a 2025-09-24 Warnings Exact identifier application number: M013 Xpect Pain Away Extra Strength ACETAMINOPHEN ASPIRIN CAFFEINE Cintas Corporation 1269d069-afaf-4ca5-b369-f74249a348db 2025-09-24 Warnings Exact identifier application number: M013 Aspirin Low Dose ASPIRIN Preferred Pharmaceuticals Inc. 29214eec-860c-43f0-83c6-9ed5a9f530af 2025-09-22 Warnings Exact identifier application number: M013 ASPIRIN ASPIRIN Kroger Company bbee8ee4-e09d-3ba6-e053-2a95a90af647 2025-09-19 Warnings Exact identifier application number: M013 careone acetaminophen ACETAMINOPHEN American Sales Company 4bb696f6-a47b-4da9-9224-9aeae3e152f3 2025-09-19 Warnings Exact identifier application number: M013 Childrens Pain Relief ACETAMINOPHEN Aurohealth LLC 49a740ec-8ed4-4c76-b2d0-c13651bafa5e 2025-09-18 Warnings Exact identifier application number: M013 Extra Strength Headache Relief ACETAMINOPHEN, ASPIRIN, AND CAFFEINE Advanced Rx LLC a7ed4c76-a5b5-44f7-866f-f43790e45c78 2025-09-18 Warnings Exact identifier application number: M013 acetaminophen ACETAMINOPHEN CVS Pharmacy fc2d4367-8884-4b76-aa3e-8c35be1ace49 2025-09-18 Warnings Exact identifier application number: M013 Aspirin Enteric Coated, Regular Strength ASPIRIN Walgreen Company 5e1484d3-5be1-40da-a3bf-fb19f7d27d45 2025-09-18 Warnings Exact identifier application number: M013 TYLENOL Extra Strength ACETAMINOPHEN Kenvue Brands LLC ab02080a-c903-4e4a-a9f3-2b8197ed2f2b 2025-09-17 Warnings Exact identifier application number: M013 Childrens TYLENOL ACETAMINOPHEN Kenvue Brands LLC 79669930-f744-4bb1-8325-b75951489b64 2025-09-17 Warnings Exact identifier application number: M013 Pain Reliever PM Extra Strength ACETAMINOPHEN, DIPHENHYDRAMINE HCL L.N.K. International, Inc. ff199db8-c7ea-4b6e-ad8b-3ceeca883d92 2025-09-15 Warnings Exact identifier application number: M013 Acetaminophen PM Extra Strength ACETAMINOPHEN, DIPHENHYDRAMINE HCL FOODHOLD U.S.A., LLC fdd7ce80-d6be-41b9-affd-d024cf306b50 2025-09-12 Warnings Exact identifier application number: M013 Extra Strength Pain Reliever ACETAMINOPHEN INGLES MARKETS, INC. 3e89240b-0e27-fde4-e063-6394a90a779f 2025-09-11 Warnings Exact identifier application number: M013 Aspirin 81 mg Low Dose ASPIRIN HEB 926fe7b6-9607-469f-912f-4019891067a9 2025-09-10 Warnings Exact identifier application number: M013
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 59779-334-07 59779033407 1 BOTTLE, PLASTIC in 1 CARTON (59779-334-07) > 36 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2008-03-13 0000-00-00 No No Current