Itch Relief

Product NDC: 59779-708
11-digit product format: 597790708
Labeler code: 59779
Product ID: 59779-708_7f87375a-df1f-4d02-a88d-6c969deebeff
Type: HUMAN OTC DRUG
Nonproprietary name: Diphenhydramine Hydrochloride, Zinc Acetate
Dosage form: CREAM
Route: TOPICAL
Labeler: CVS Pharmacy
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2005-06-08
Substance: DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
Active strength: 2; .1 g/100g; g/100g
Pharmacologic classes: Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Itch Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DIPHENHYDRAMINE HYDROCHLORIDE	2 g/100g
ZINC ACETATE	.1 g/100g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
TC2D6JAD40	Internal UNII lookup
FM5526K07A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1087026	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
0e988da1-1904-431d-a152-bdb2aacc8e16	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
59779-708-64	Itch Relief	1 in 1 CARTON	CREAM	1		12
59779-708-64	Itch Relief	28 g in 1 TUBE	CREAM	28		12

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
DIPHENHYDRAMINE HYDROCHLORIDE	ACTIVE INGREDIENT	TC2D6JAD40	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
ZINC ACETATE	ACTIVE INGREDIENT	FM5526K07A	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
DIPHENHYDRAMINE	ACTIVE MOIETY	8GTS82S83M	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
ZINC CATION	ACTIVE MOIETY	13S1S8SF37	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
CETYL ALCOHOL	INACTIVE INGREDIENT	936JST6JCN	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
DIAZOLIDINYL UREA	INACTIVE INGREDIENT	H5RIZ3MPW4	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
PEG-2 STEARATE	INACTIVE INGREDIENT	94YQ11Y95F	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
PEG-20 STEARATE	INACTIVE INGREDIENT	NBX892EA57	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3
WATER	INACTIVE INGREDIENT	059QF0KO0R	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
59779-708	ITCH RELIEF (DIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE) CREAM [CVS PHARMACY]	12	Current NDC, Legacy NDC, 2 package rows	20240926_0e988da1-1904-431d-a152-bdb2aacc8e16.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 22 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Eagle Brand Muscle Rub	MENTHOL, METHYL SALICYLATE	Borden Company (Private) Limited	06cb845c-cc53-1f1d-e063-6394a90a8c01	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Oil Aromatic	CAMPHOR, MENTHOL, METHYL SALICYLATE	PT. EAGLE INDO PHARMA	0ef7c3aa-94a3-9fe9-e063-6394a90ab13d	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Oil	MENTHOL, METHYL SALICYLATE	PT. EAGLE INDO PHARMA	5071f145-49f7-0855-e063-6394a90a8f26	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Oil Refresh	CAMPHOR, MENTHOL	PT. EAGLE INDO PHARMA	09260c31-56a3-07aa-e063-6394a90a95fd	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Muscle Rub	MENTHOL, METHYL SALICYLATE	PT. EAGLE INDO PHARMA	5072ad57-9fa7-ddba-e063-6394a90a319b	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Roll On Refresh	CAMPHOR, MENTHOL	PT. EAGLE INDO PHARMA	09235f26-2262-6ca2-e063-6394a90ad8f1	2026-04-27	Warnings	Exact identifier application number: M017
Eagle Brand Medicated Roll On Aromatic	CAMPHOR, MENTHOL, METHYL SALICYLATE	PT. EAGLE INDO PHARMA	0f333f93-bec6-72d5-e063-6394a90a4e3f	2026-04-27	Warnings	Exact identifier application number: M017
HIP PAIN RELIEF ROLL-ON	LIDOCAINE AND MENTHOL	Guangzhou Liuquanmiao Import & Export Trade Co., Ltd.	502f1f9e-8552-ca7b-e063-6394a90a7c53	2026-04-24	Warnings	Exact identifier application number: M017
SOMBRA WARM THERAPY	MENTHOL CAMPHOR	SOMBRA COSMETICS INC.	de78dba9-53b3-4dbd-9dd2-6a692378da34	2026-04-24	Warnings	Exact identifier application number: M017
Rite Aid Itch Relief	DIPHENHYDRAMINE HCL 2%, ZINC ACETATE 0.1%	Rite Aid	e285df43-317c-d862-e053-2a95a90acdce	2026-04-23	Warnings	Exact identifier application number: M017
FixMySkin Healing Balm Unflavored	HYDROCORTISONE	Lovely Skin, Inc.	9ff8db07-ad6d-4865-a534-94bd8312957e	2026-04-23	Warnings	Exact identifier application number: M017
DCH Labs Cortisone	HYDROCORTISONE 1%	Derma Care Research Labs	5025f53a-02e0-0f6a-e063-6394a90adbbf	2026-04-23	Warnings	Exact identifier application number: M017
Hydrocortisone 1%	HYDROCORTISONE	Preferred Pharmaceuticals Inc.	e0f46445-64c5-4f5d-90b0-3fa07ed7d1b4	2026-04-22	Warnings	Exact identifier application number: M017
Dr. Carrasco Pain Relief	MENTHOL	Carrasco Enterprises, Inc.	befa8526-f468-428e-a829-422c2ea48612	2026-04-21	Warnings	Exact identifier application number: M017
HealthWise Feminine Anti-itch Cream	BENZOCAINE, RESORCINOL	Veridian Healthcare	4ff88b9e-5869-a1cb-e063-6294a90a87b7	2026-04-21	Warnings	Exact identifier application number: M017
SOMBRA COOL THERAPY	MENTHOL	SOMBRA COSMETICS INC.	87e9b16b-1cab-48f7-b9e4-1c3eaeeb3ca3	2026-04-21	Warnings	Exact identifier application number: M017
Careland Lidocaine Pain Relieving	LIDOCAINE	Planet (Anhui) Pharmaceutical Co., Ltd.	c4c86a8f-1d57-49d2-a65f-acb0dccf2f87	2026-04-21	Warnings	Exact identifier application number: M017
KOXUO Arnica Bruise Cream	ARNICA BRUISE CREAM	Guangzhou Jingliang Cosmetics Co., Ltd.	5003bf83-fa01-b01a-e063-6294a90ad37f	2026-04-21	Warnings	Exact identifier application number: M017
KT Pain Relief Cream Magnesium with Arnica and 4% Lidocaine	KT PAIN RELIEF CREAM MAGNESIUM WITH ARNICA AND 4% LIDOCAINE ROLLON	Clarion Brands LLC	4f82993c-ebc4-5787-e063-6294a90a12d6	2026-04-20	Warnings	Exact identifier application number: M017
KT Pain Relief Cream Magnesium with Cooling 5% Menthol	KT PAIN RELIEF CREAM MAGNESIUM WITH COOLING 5% MENTHOL	Clarion Brands LLC	4fe64056-f3c6-bc76-e063-6294a90a7e62	2026-04-20	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
TC2D6JAD40	DIPHENHYDRAMINE HYDROCHLORIDE	147-24-0	DIPHENHYDRAMINE HYDROCHLORIDE
FM5526K07A	ZINC ACETATE	5970-45-6	ZINC ACETATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1087026	diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Cream	PSN	0e988da1-1904-431d-a152-bdb2aacc8e16	12
1087026	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream	SCD	0e988da1-1904-431d-a152-bdb2aacc8e16	12
1087026	diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Cream	SY	0e988da1-1904-431d-a152-bdb2aacc8e16	12

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
59779-708-64	59779070864	1 TUBE in 1 CARTON (59779-708-64) / 28 g in 1 TUBE	1 tube	2005-06-08	0000-00-00	No	No	Current