Auryxia

Product NDC
59922-631
11-digit product format
599220631
Labeler code
59922
Product ID
59922-631_79cb63af-94fa-4f49-91d3-543c0058cd4e
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ferric citrate
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Akebia Therapeutics, Inc.
Application
NDA205874
Marketing category
NDA
Marketing start
2014-09-17
Substance
TETRAFERRIC TRICITRATE DECAHYDRATE
Active strength
210 mg/1
Pharmacologic classes
Iron [CS], Parenteral Iron Replacement [EPC], Phosphate Binder [EPC], Phosphate Chelating Activity [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 4 matching rows.

View current auxiliary records. · View the auxiliary file history.

Dataset, Scope, Package NDC table
DatasetScopePackage NDC
excluded productproduct
excluded packagepackage59922-631-92
excluded packagepackage59922-631-01
excluded packagepackage59922-631-91

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205874-001AURYXIAFERRIC CITRATEEQ 210MG IRONTABLET / ORALABRLD, RS2014-09-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N205874-001AB

Orange Book patents#

Current patent rows page 1 of 1 · 3 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205874-00180934232026-04-21U-15772014-10-02
N205874-001103000392030-07-21U-25492019-06-24
N205874-00193871912030-07-21Drug product2016-08-09

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-0587673890dc5c…
2021-03-12 10:30 UTC2021-03N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-053f01610625f2…
2019-09-15 20:21 UTC2019-09N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05b00525d2431f…
2019-07-19 19:46 UTC2019-07N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-053f0d92c62455…
2023-05-13 08:27 UTC2023-05N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05053a50430f4f…
2023-01-26 05:58 UTC2023-01N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N205874-001AURYXIAEQ 210MG IRONTABLET / ORALRLD, RS2014-09-05cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N205874-001AB1a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 14 · 526 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205874-00180934232026-04-21U-15772014-10-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205874-001103000392030-07-21U-25492019-06-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205874-00193871912030-07-21Drug product2016-08-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205874-00180934232026-04-21U-15772014-10-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205874-001103000392030-07-21U-25492019-06-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205874-00193871912030-07-21Drug product2016-08-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N205874-00180934232026-04-21U-15772014-10-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205874-001103000392030-07-21U-25492019-06-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205874-00193871912030-07-21Drug product2016-08-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205874-00180934232026-04-21U-15772014-10-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205874-001103000392030-07-21U-25492019-06-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205874-00193871912030-07-21Drug product2016-08-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205874-00180934232026-04-21U-15772014-10-02b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205874-001103000392030-07-21U-25492019-06-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205874-00193871912030-07-21Drug product2016-08-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00177678512024-02-18Drug substance, Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00182992982024-02-18Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00183386422024-02-18U-1577Drug substance, Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00186098962024-02-18Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00187542572024-02-18Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00187542582024-02-18Drug product2014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00188469762024-02-18U-15772014-11-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00189013492024-02-18U-15772015-03-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00190503162024-02-18U-15772015-07-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00193281332024-02-18U-1577Drug substance, Drug product2016-12-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00197574162024-02-18U-1577Drug substance, Drug product2017-10-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00180934232026-04-21U-15772014-10-0203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-001103000392030-07-21U-25492019-06-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205874-00193871912030-07-21Drug product2016-08-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00177678512024-02-18Drug substance, Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00182992982024-02-18Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00183386422024-02-18U-1577Drug substance, Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00186098962024-02-18Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00187542572024-02-18Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00187542582024-02-18Drug product2014-10-022680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00188469762024-02-18U-15772014-11-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00189013492024-02-18U-15772015-03-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00190503162024-02-18U-15772015-07-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00193281332024-02-18U-1577Drug substance, Drug product2016-12-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205874-00197574162024-02-18U-1577Drug substance, Drug product2017-10-052680178bc6a6…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N205874-001I-7902020-11-0674a2ff9319b5…
2020-12-22 03:56 UTC2020-12N205874-001I-7902020-11-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205874-001I-7902020-11-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205874-001I-7902020-11-063f01610625f2…
2019-09-15 20:21 UTC2019-09N205874-001I-7902020-11-06b00525d2431f…
2019-07-19 19:46 UTC2019-07N205874-001I-7902020-11-06ea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Auryxia
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TETRAFERRIC TRICITRATE DECAHYDRATE210 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
Q91187K011Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1594680Internal RxNorm lookup
1596023Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
aadd18e0-3752-11e4-8510-0800200c9a66Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
04cdd491-d111-4bc2-9549-75c575e1bd4bProduct name120200714
8390fb8b-6c75-416c-a9a1-70e8ed493b73Product name120200611
96a528e9-23e2-495f-81b9-ae87df2f7552Product name120191120
3df56c93-5837-4523-aac2-4b1ec48b9676Product name220160719
a883b7cc-d320-41d7-92ae-c873457ae641Product name120151116
bb23e78e-9e64-4037-a1c1-0e1d8762700eProduct name120150325
ef06c001-572c-d95e-42f6-ee83da75673aProduct name120140508
fd21f957-6863-d07b-5a35-250186878716Product name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
59922-631-01Auryxia200 in 1 BOTTLETABLET, FILM COATED20027

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
59922-631-01EA - Each59922-631dd188bca-ec84-4b3d-b1ac-159a59bc011b12014-10-03

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
TETRAFERRIC TRICITRATE DECAHYDRATEACTIVE INGREDIENTQ91187K011AURYXIA (FERRIC CITRATE) TABLET, COATED [KERYX BIOPHARMACEUTICALS, INC.]7
FERRIC CATIONACTIVE MOIETY91O4LML611AURYXIA (FERRIC CITRATE) TABLET, COATED [KERYX BIOPHARMACEUTICALS, INC.]7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
59922-631AURYXIA (FERRIC CITRATE) TABLET, FILM COATED [AKEBIA THERAPEUTICS, INC.]26Current NDC, Legacy NDC, 1 package rows20241222_aadd18e0-3752-11e4-8510-0800200c9a66.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AuryxiaFERRIC CITRATEAkebia Therapeutics, Inc.aadd18e0-3752-11e4-8510-0800200c9a662024-12-04Warnings, Adverse reactionsExact identifier
application applno (NDA): 205874
application number: NDA205874
ndc (product): 59922-631
Ferric CitrateFERRIC CITRATEMylan Pharmaceuticals Inc.8e8396fa-288b-402e-82b0-b1007d1b571f2024-06-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 205874
application number: NDA205874

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1596023Auryxia (iron) 210 MG Oral TabletPSNaadd18e0-3752-11e4-8510-0800200c9a6627
1594680ferric citrate (as iron) 210 MG Oral TabletPSNaadd18e0-3752-11e4-8510-0800200c9a6627
1596023ferric citrate 1000 MG Oral Tablet [Auryxia]SBDaadd18e0-3752-11e4-8510-0800200c9a6627
1594680ferric citrate 1000 MG Oral TabletSCDaadd18e0-3752-11e4-8510-0800200c9a6627
1596023Auryxia 1 GM (iron 210 MG) Oral TabletSYaadd18e0-3752-11e4-8510-0800200c9a6627
1596023Auryxia 1000 MG Oral TabletSYaadd18e0-3752-11e4-8510-0800200c9a6627
1594680ferric citrate 1 GM (iron 210 MG) Oral TabletSYaadd18e0-3752-11e4-8510-0800200c9a6627
1594680ferric citrate 1 GM Oral TabletSYaadd18e0-3752-11e4-8510-0800200c9a6627

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
59922-631-0159922063101200 TABLET, FILM COATED in 1 BOTTLE (59922-631-01) 2014-09-170000-00-00NoNoCurrent