ETOPOPHOS

Product NDC
61269-410
11-digit product format
612690410
Labeler code
61269
Product ID
61269-410_656f0cdd-f6bf-444d-ade9-f1703a31da58
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
etoposide phosphate
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
H2-Pharma, LLC
Application
NDA020457
Marketing category
NDA
Marketing start
2009-06-01
Substance
ETOPOSIDE PHOSPHATE
Active strength
100 mg/1
Pharmacologic classes
Topoisomerase Inhibitor [EPC], Topoisomerase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 6 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage61269-410-20302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage61269-410-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage61269-410-200efc9e666f02…f202fb6c5f17…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020457-001ETOPOPHOS PRESERVATIVE FREEETOPOSIDE PHOSPHATEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-174b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-1774a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-1787673890dc5c…
2021-03-12 10:30 UTC2021-03N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-175aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-178869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-173f01610625f2…
2019-09-15 20:21 UTC2019-09N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17b00525d2431f…
2019-07-19 19:46 UTC2019-07N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-176a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-171c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-173f0d92c62455…
2023-05-13 08:27 UTC2023-05N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17053a50430f4f…
2023-01-26 05:58 UTC2023-01N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-173bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-173a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N020457-001ETOPOPHOS PRESERVATIVE FREEEQ 100MG BASE/VIALINJECTABLE / INJECTIONRLD, RS1996-05-17cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
ETOPOPHOS
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ETOPOSIDE PHOSPHATE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
528XYJ8L1NInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
226719Internal RxNorm lookup
1734340Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7499fc35-fae8-44ad-bbab-9a1a589bf3eeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2ab98334-79be-46be-f4f5-d4a6cc04219eProduct name320180118
4896aaa2-df52-a28b-a484-cf928e9408caProduct name120140508
e9a73b62-e9c6-118b-a3be-022705d13855Product name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
61269-410-20ETOPOPHOS1 in 1 VIAL, SINGLE-DOSEINJECTION, POWDER, LYOPHILIZED,122
61269-410-20ETOPOPHOS1 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,122

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
61269-410-20EA - Each61269-410c118ffec-331c-404d-a9a6-add05f89779e12020-03-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
61269-410ETOPOPHOS (ETOPOSIDE PHOSPHATE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [H2-PHARMA, LLC]21Current NDC, Legacy NDC, 2 package rows20250202_7499fc35-fae8-44ad-bbab-9a1a589bf3ee.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ETOPOPHOSETOPOSIDE PHOSPHATEH2-Pharma, LLC7499fc35-fae8-44ad-bbab-9a1a589bf3ee2025-11-25Warnings, Adverse reactionsExact identifier
application applno (NDA): 020457
application number: NDA020457
ndc (product): 61269-410

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
226719ETOPOPHOS 100 MG InjectionPSN7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
1734340etoposide 100 MG InjectionPSN7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
226719etoposide 100 MG Injection [Etopophos]SBD7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
1734340etoposide 100 MG InjectionSCD7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
226719Etopophos 100 MG (as etoposide phosphate) InjectionSY7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
226719Etopophos 100 MG InjectionSY7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
1734340etoposide 100 MG (as etoposide phosphate) InjectionSY7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
1734340VP-16 100 MG InjectionSY7499fc35-fae8-44ad-bbab-9a1a589bf3ee22
226719VP-16 100 MG Injection [Etopophos]SY7499fc35-fae8-44ad-bbab-9a1a589bf3ee22

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
61269-410-20612690410201 VIAL, SINGLE-DOSE in 1 CARTON (61269-410-20) / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL, SINGLE-DOSE2009-06-010000-00-00NoNoCurrent