Etoposide

Product NDC
63323-104
11-digit product format
633230104
Labeler code
63323
Product ID
63323-104_d672a555-bb0e-4a82-ac5e-5c9393b59c28
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ETOPOSIDE
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Fresenius Kabi USA, LLC
Application
ANDA074983
Marketing category
ANDA
Marketing start
2001-07-18
Substance
ETOPOSIDE
Active strength
20 mg/mL
Pharmacologic classes
Topoisomerase Inhibitor [EPC], Topoisomerase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074983-001ETOPOSIDEETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A074983-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-3087673890dc5c…
2021-03-12 10:30 UTC2021-03A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-303f01610625f2…
2019-09-15 20:21 UTC2019-09A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30b00525d2431f…
2019-07-19 19:46 UTC2019-07A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-303f0d92c62455…
2023-05-13 08:27 UTC2023-05A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30053a50430f4f…
2023-01-26 05:58 UTC2023-01A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074983-001ETOPOSIDE20MG/MLINJECTABLE / INJECTIONAPRS1998-09-30e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A074983-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A074983-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074983-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074983-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074983-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074983-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074983-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074983-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074983-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074983-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074983-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074983-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074983-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074983-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074983-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074983-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074983-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074983-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074983-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074983-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074983-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074983-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A074983-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074983-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074983-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074983-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A074983-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A074983-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074983-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074983-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074983-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074983-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074983-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074983-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074983-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A074983-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A074983-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074983-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074983-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074983-001AP1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Etoposide
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ETOPOSIDE20 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6PLQ3CP4P3Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
310248Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fe870629-104d-4d67-a7c6-f53bc588121eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2ab98334-79be-46be-f4f5-d4a6cc04219eProduct name320180118
4896aaa2-df52-a28b-a484-cf928e9408caProduct name120140508
e9a73b62-e9c6-118b-a3be-022705d13855Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63323-104-01Etoposide1 in 1 BOXINJECTION, SOLUTION16
63323-104-01Etoposide5 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION56
63323-104-05Etoposide10 in 1 CARTONINJECTION, SOLUTION106
63323-104-06Etoposide1 in 1 CARTONINJECTION, SOLUTION16
63323-104-06Etoposide5 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION56
63323-104-25Etoposide25 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION256
63323-104-25Etoposide1 in 1 CARTONINJECTION, SOLUTION16
63323-104-50Etoposide1 in 1 CARTONINJECTION, SOLUTION16
63323-104-50Etoposide50 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION506

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63323-104-01ML - Milliliter63323-10481083c41-85e6-450e-bb64-3e96b6a74a3c12020-03-10
63323-104-05ML - Milliliter63323-104737e6d1b-70ff-458e-bd0e-d549b8c9c14c12013-02-13
63323-104-06ML - Milliliter63323-104306edf37-1ce9-46fb-9318-e4a089f7a40712024-07-12
63323-104-25ML - Milliliter63323-10476b46cb3-d8a7-478c-8259-62f5f7a4be8c12013-02-13
63323-104-50ML - Milliliter63323-1049fd84189-0583-49c6-819d-b325d158104512013-02-13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ETOPOSIDEACTIVE INGREDIENT6PLQ3CP4P3ETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
ETOPOSIDEACTIVE MOIETY6PLQ3CP4P3ETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
ALCOHOLINACTIVE INGREDIENT3K9958V90METOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
BENZYL ALCOHOLINACTIVE INGREDIENTLKG8494WBHETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
CITRIC ACID MONOHYDRATEINACTIVE INGREDIENT2968PHW8QPETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
POLYETHYLENE GLYCOL 300INACTIVE INGREDIENT5655G9Y8AQETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HETOPOSIDE INJECTION, SOLUTION [APP PHARMACEUTICALS, LLC]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63323-104ETOPOSIDE (ETOPOSIDE) INJECTION, SOLUTION [FRESENIUS KABI USA, LLC]6Current NDC, Legacy NDC, 9 package rows20220612_fe870629-104d-4d67-a7c6-f53bc588121e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EtoposideETOPOSIDEFresenius Kabi USA, LLCfe870629-104d-4d67-a7c6-f53bc588121e2026-07-14Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074983
application number: ANDA074983
ndc (product): 63323-104

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
310248etoposide 20 MG/ML Injectable SolutionPSNfe870629-104d-4d67-a7c6-f53bc588121e6
310248etoposide 20 MG/ML Injectable SolutionSCDfe870629-104d-4d67-a7c6-f53bc588121e6
310248etoposide (as etoposide phosphate) 20 MG/ML Injectable SolutionSYfe870629-104d-4d67-a7c6-f53bc588121e6
310248VP-16 20 MG/ML Injectable SolutionSYfe870629-104d-4d67-a7c6-f53bc588121e6

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
63323-104-01633230104011 in 1 BOXHistorical
63323-104-056332301040510 BOX in 1 CARTON (63323-104-05) / 1 VIAL, MULTI-DOSE in 1 BOX (63323-104-01) / 5 mL in 1 VIAL, MULTI-DOSE10 box2001-07-180000-00-00NoNoCurrent
63323-104-06633230104061 VIAL, MULTI-DOSE in 1 CARTON (63323-104-06) / 5 mL in 1 VIAL, MULTI-DOSE2022-09-090000-00-00NoNoCurrent
63323-104-25633230104251 VIAL, MULTI-DOSE in 1 CARTON (63323-104-25) / 25 mL in 1 VIAL, MULTI-DOSE2001-07-180000-00-00NoNoCurrent
63323-104-50633230104501 VIAL, MULTI-DOSE in 1 CARTON (63323-104-50) / 50 mL in 1 VIAL, MULTI-DOSE2001-07-180000-00-00NoNoCurrent