roflumilast

Product NDC
64380-786
11-digit product format
643800786
Labeler code
64380
Product ID
64380-786_9c3f4a61-0aed-418d-b77f-a1864bedee71
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ROFLUMILAST
Dosage form
TABLET
Route
ORAL
Labeler
Strides Pharma Science Limited
Application
ANDA208247
Marketing category
ANDA
Marketing start
2022-10-13
Substance
ROFLUMILAST
Active strength
500 ug/1
Pharmacologic classes
Phosphodiesterase 4 Inhibitor [EPC], Phosphodiesterase 4 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A208247-001ROFLUMILASTROFLUMILAST500MCGTABLET / ORALAB2020-03-30
A208247-002ROFLUMILASTROFLUMILAST250MCGTABLET / ORALAB2023-06-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A208247-001AB
A208247-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 60 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30caaa826d4ba7…
2026-08-18 06:07:402026-07A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-3079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-301e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-308072bd15b7f6…
2024-05-31 18:47 UTC2024-05A208247-002ROFLUMILAST250MCGTABLET / ORALAB2023-06-208072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-304b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-3087673890dc5c…
2021-03-12 10:30 UTC2021-03A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-30c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A208247-001ROFLUMILAST500MCGTABLET / ORALAB2020-03-306a51e52b5d6a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 60 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A208247-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A208247-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A208247-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208247-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208247-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208247-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A208247-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208247-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208247-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208247-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208247-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208247-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208247-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208247-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208247-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208247-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208247-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208247-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208247-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208247-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A208247-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A208247-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208247-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208247-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208247-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208247-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208247-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208247-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A208247-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A208247-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208247-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A208247-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A208247-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A208247-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A208247-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A208247-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A208247-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A208247-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A208247-001AB1c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A208247-001AB16a51e52b5d6a…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2023-12-20 04:57 UTC2023-12A208247-001PC2023-04-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A208247-001PC2023-04-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A208247-001PC2023-04-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A208247-001PC2023-04-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A208247-001PC2023-04-173f0d92c62455…
2023-05-13 08:27 UTC2023-05A208247-001PC2023-04-17053a50430f4f…
2023-01-26 05:58 UTC2023-01A208247-001PC2023-04-173bdfa0b2c4d7…

Additional Listing Data#

Finished product
Yes
Brand name base
roflumilast
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ROFLUMILAST500 ug/1

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
dcb8b904-8d4f-458b-b954-4eae028a2651Product name220250305
a1a743b6-f2e2-4044-a176-5c60c71ece24Product name120250102
6ac6be18-9820-1c07-b72b-a35dcf9d14c7Product name920240501

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
64380-786-01roflumilast30 in 1 BOTTLETABLET308
64380-786-05roflumilast90 in 1 BOTTLETABLET908

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
64380-786ROFLUMILAST TABLET [STRIDES PHARMA SCIENCE LIMITED]6Current NDC, Legacy NDC, 2 package rows20230322_78d2644d-b62c-48f5-8407-2adf09bcb144.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
roflumilastROFLUMILASTAvKARE55009549-3f0c-1f58-e063-6294a90a6c032026-06-24Warnings, Adverse reactionsExact identifier
application applno (ANDA): 208247
application number: ANDA208247

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2001319roflumilast 250 MCG Oral TabletPSN78d2644d-b62c-48f5-8407-2adf09bcb1448
1091839roflumilast 500 MCG Oral TabletPSN78d2644d-b62c-48f5-8407-2adf09bcb1448
2001319roflumilast 0.25 MG Oral TabletSCD78d2644d-b62c-48f5-8407-2adf09bcb1448
1091839roflumilast 0.5 MG Oral TabletSCD78d2644d-b62c-48f5-8407-2adf09bcb1448
2001319roflumilast 250 MCG Oral TabletSY78d2644d-b62c-48f5-8407-2adf09bcb1448
1091839roflumilast 500 MCG Oral TabletSY78d2644d-b62c-48f5-8407-2adf09bcb1448

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
64380-786-016438007860130 TABLET in 1 BOTTLE (64380-786-01) 30 tablet2022-10-130000-00-00NoNoCurrent
64380-786-056438007860590 TABLET in 1 BOTTLE (64380-786-05) 90 tablet2022-10-130000-00-00NoNoCurrent