EXPAREL

Product NDC
65250-266
11-digit product format
652500266
Labeler code
65250
Product ID
65250-266_7dd52279-ea2e-4f8c-8e29-8172bc3ed882
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
bupivacaine
Dosage form
INJECTION, SUSPENSION, LIPOSOMAL
Route
INFILTRATION
Labeler
Pacira Pharmaceuticals, Inc.
Application
NDA022496
Marketing category
NDA
Marketing start
2012-01-01
Substance
BUPIVACAINE
Active strength
13.3 mg/mL
Pharmacologic classes
Amide Local Anesthetic [EPC], Amides [CS], Local Anesthesia [PE]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Additional Listing Data#

Finished product
Yes
Brand name base
EXPAREL
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BUPIVACAINE13.3 mg/mL

Harmonized Identifiers#

Field, Values table
FieldValues
UniiY8335394RO
Rxcui1191508, 1191513, 1745061, 1745062

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cbf85893-59ef-423f-87d4-a573c000a8b9Product name820250731
5dad6767-dcd1-b0da-8727-7f3f7bc3a435Product name220250303
e3a99641-4540-4894-9108-00cab3c57b7eProduct name120211207
5da98533-f072-406b-9e1b-6ac19eca9926Product name120210622
306b993e-3140-4823-ad5e-88b708f9d2acProduct name120210510
a831e694-3663-4a83-82be-6c309429f750Product name220200608

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
65250-266-04EXPAREL4 in 1 CARTONINJECTION, SUSPENSION, LIPOSOMAL432
65250-266-09EXPAREL10 in 1 CARTONINJECTION, SUSPENSION, LIPOSOMAL1032
65250-266-20EXPAREL20 mL in 1 VIALINJECTION, SUSPENSION, LIPOSOMAL2032

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
65250-266-04ML - Milliliter65250-266ec46846f-9944-4e6d-a959-dd45f0ab03ab12017-04-05
65250-266-09ML - Milliliter65250-2664af6a36d-5755-4bf5-a7b6-4c1e69c2514c12017-03-06
65250-266-20ML - Milliliter65250-266d9fc2b4c-b59b-4707-8e69-dc8e5f11ce4512012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
BUPIVACAINEACTIVE INGREDIENTY8335394ROEXPAREL (BUPIVACAINE) INJECTION, SUSPENSION, LIPOSOMAL [PACIRA PHARMACEUTICALS INC.]6
BUPIVACAINEACTIVE MOIETYY8335394ROEXPAREL (BUPIVACAINE) INJECTION, SUSPENSION, LIPOSOMAL [PACIRA PHARMACEUTICALS INC.]6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
65250-266EXPAREL (BUPIVACAINE) INJECTION, SUSPENSION, LIPOSOMAL [PACIRA PHARMACEUTICALS, INC.]31Current NDC, Legacy NDC, 3 package rows20241218_bb5a9e59-0f51-11df-8a39-0800200c9a66.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1745061BUPivacaine liposome 1.3 % in 10 ML InjectionPSNbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191508BUPivacaine liposome 1.3 % in 20 ML InjectionPSNbb5a9e59-0f51-11df-8a39-0800200c9a6632
1745062EXPAREL 1.3 % in 10 ML InjectionPSNbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191513EXPAREL 1.3 % in 20 ML InjectionPSNbb5a9e59-0f51-11df-8a39-0800200c9a6632
174506210 ML bupivacaine liposome 13.3 MG/ML Injection [Exparel]SBDbb5a9e59-0f51-11df-8a39-0800200c9a6632
119151320 ML bupivacaine liposome 13.3 MG/ML Injection [Exparel]SBDbb5a9e59-0f51-11df-8a39-0800200c9a6632
174506110 ML bupivacaine liposome 13.3 MG/ML InjectionSCDbb5a9e59-0f51-11df-8a39-0800200c9a6632
119150820 ML bupivacaine liposome 13.3 MG/ML InjectionSCDbb5a9e59-0f51-11df-8a39-0800200c9a6632
174506210 ML Exparel 13.3 MG/ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
119151320 ML Exparel 13.3 MG/ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191508bupivacaine liposome 1.3 % in 20 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1745061bupivacaine liposome 133 MG per 10 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191508bupivacaine liposome 266 MG per 20 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191513Exparel 1.3 % in 20 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1745062Exparel 133 MG per 10 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632
1191513Exparel 266 MG per 20 ML InjectionSYbb5a9e59-0f51-11df-8a39-0800200c9a6632

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
65250-266-04652500266044 VIAL in 1 CARTON (65250-266-04) / 20 mL in 1 VIAL (65250-266-20) 4 vial2016-09-280000-00-00NoNoCurrent
65250-266-096525002660910 VIAL in 1 CARTON (65250-266-09) / 20 mL in 1 VIAL (65250-266-20) 10 vial2017-03-310000-00-00NoNoCurrent
65250-266-206525002662020 mL in 1 VIAL20 mlHistorical